HYDROCEPHALUS

作品数:109被引量:122H指数:6
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相关领域:医药卫生更多>>
相关作者:谭亮陈鑫李俊田恒力乔梁更多>>
相关机构:华中科技大学第三军医大学西南医院南京军区南京总医院杭州市第六人民医院更多>>
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相关基金:国家自然科学基金上海市浦江人才计划项目广东省自然科学基金国家重点基础研究发展计划更多>>
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Novel insights into non-coding RNAs and their role in hydrocephalus
《Neural Regeneration Research》2026年第2期636-647,共12页Zhiyue Cui Jian He An Li Junqiang Wang Yijian Yang Kaiyue Wang Zhikun Liu Qian Ouyang Zhangjie Su Pingsheng Hu Gelei Xiao 
supported by the National Natural Science Foundation of China,Nos.82171347,82371362;the Natural Science Foundation of Hunan Province,No.2022JJ30971;the Scientific Research Project of Hunan Provincial Health Commission of China,No.202204040024(all to GX).
A large body of evidence has highlighted the role of non-coding RNAs in neurodevelopment and neuroinflammation.This evidence has led to increasing speculation that non-coding RNAs may be involved in the pathophysiolog...
关键词:HYDROCEPHALUS NEURODEVELOPMENT NEUROINFLAMMATION non-coding RNA therapeutic target 
A Comprehensive Review of Pediatric Hydrocephalus
《Open Journal of Pediatrics》2025年第1期21-37,共17页Lakshmi C. Devarapalli Kelley J. Williams Terry L. Oroszi 
Hydrocephalus is a medical condition caused by an abnormal cerebrospinal fluid (CSF) buildup in the brain’s ventricles. This excess fluid causes the ventricles to enlarge, increasing pressure within the brain. CSF ty...
关键词:HYDROCEPHALUS CSF VENTRICLES PATHOGENESIS PEDIATRIC 
RGS22 maintains the physiological function of ependymal cells to prevent hydrocephalus
《Science China(Life Sciences)》2025年第2期441-453,共13页Xue Pang Lin Gu Qiu-Ying Han Jia-Qing Xing Ming Zhao Shao-Yi Huang Jun-Xi Yi Jie Pan Hao Hong Wen Xue Xue-Qing Zhou Zhi-Hui Su Xin-Ran Zhang Li-Ming Sun Shao-Zhen Jiang Dan Luo Ling Chen Zheng-Jie Wang Yu Yu Tian Xia Xue-Min Zhang Ai-Ling Li Tao Zhou Hong Cai Tao Li 
supported by grants from the China National Natural Science Foundation(82130052 and 81925017 to Tao Li,82001690 to Hong Cai)。
Ependymal cells line the wall of cerebral ventricles and ensure the unidirectional cerebrospinal fluid(CSF)flow by beating their motile cilia coordinately.The ependymal denudation or ciliary dysfunction causes hydroce...
关键词:RGS22 HYDROCEPHALUS ependymal cells 
Dynamic plain abdominal film provides simple and effective diagnosis of delayed shunt insufficiency caused by abdominal adhesions after VP shunt
《Chinese Neurosurgical Journal》2024年第4期256-265,共10页Zhiqiang Liu Jintao Chen Chaoqun Weng Bei Liu Zhixiong Lin 
Background Many complications may occur after placement of the ventriculoperitoneal shunt (VP shunt) for hydrocephalus, and delayed shunt insufficiency (DSI) is among the most common. It is often caused by abdominal a...
关键词:HYDROCEPHALUS VP shunt DELAYED Shunt insufficiency 
Fabrication and in vivo testing of a sub-mm duckbill valve for hydrocephalus treatment
《Microsystems & Nanoengineering》2024年第6期391-402,共12页Yuna Jung Daniel Gulick Jennifer Blain Christen 
supported by DOD-ARMY:Army Medical Research Acquisition Activity(USAMRAA)under a CDMRP(Congressionally Directed Medical Research Program)grant W81XWH2010805,“A Miniaturized Valve that Mimics Functional Arachnoid Granulations to Treat Hydrocephalus”.
Hydrocephalus is characterized by the accumulation of excess cerebrospinal fluid(CSF)in the cranium due to an imbalance between production and absorption of CSF.The standard treatment involves the implantation of a sh...
关键词:testing TREATMENT DUCK 
Choroid plexus CCL2‒CCR2 signaling orchestrates macrophage recruitment and cerebrospinal fluid hypersecretion in hydrocephalus
《Acta Pharmaceutica Sinica B》2024年第10期4544-4559,共16页Qiguang Wang Fei Liu Yue Li Huan Zhang Xin Qi Ke Wu Yi Zhang Shenglan You Wenke Liu Xuhui Hui Hanmei Li Lei Zhu Huile Gao Jian Cheng 
the National Natural Science Foundation of China(82201501);the Natural Science Foundation of Sichuan Province(2023NSFC1581,China);1·3.5 projects for disciplines of excellence-Clinical Research Incubation Project,West China Hospital,Sichuan University(No.2020HXFH013,China);Sichuan Science and Technology Program(22ZDYF2619,China)for financial support.
The choroid plexus(ChP)serves as the principal origin of cerebrospinal fluid(CSF).CSF hypersecretion due to ChP inflammation has emerged as an important pathogenesis of hydrocephalus recently.Nevertheless,the precise ...
关键词:HYDROCEPHALUS MACROPHAGES CCL2 CCR2 Choroid plexus Epithelial cells CROSSTALK Cerebrospinal fluid hypersecretion 
Hydrocephalus Secondary to Intraventricular Myxopapillary Ependymoma: Case Report
《World Journal of Neuroscience》2024年第3期85-91,共7页Juan Carlos Ayala-Alvarez Onyekachi Emmanuel Anyagwa Fátima Gabriela Macías-Ortiz Oluwatoyin Adalia Dairo Courtney Storm Truebody Reza Badrnejad Aishwarya Bhuta Shashwat Sandeep Phade Srushti Kishor Jamdar Mostafa Yassin Vismaja Vijayan 
Ependymomas are a somewhat diverse category of glial tumors that often develop from the lining of the brain’s ventricles, or the spinal cord’s central canal. They make up 5% of all neuroepithelial tumors, 10% of pae...
关键词:HYDROCEPHALUS Myxopapillary Ependymoma (MPE) PAEDIATRICS NEUROSURGERY GLIOMA Intracranial Hypertension 
Intervention at an early threshold for post-hemorrhagic ventricular dilatation in preterm infants: a systematic review and meta-analysis
《World Journal of Pediatrics》2024年第8期774-786,共13页Patrick Blundell Lloyd Abood Mallinath Chakraborty Sujoy Banerjee 
Background Very few adequately powered studies exploring early thresholds for intervention in the management of post-hemorrhagic ventricular dilatation(PHVD)in preterm infants have identified consistent neurodevelopme...
关键词:HYDROCEPHALUS Intraventricular hemorrhage Lumbar puncture MORTALITY NEURODEVELOPMENT Preterm infants 
A polarized multicomponent foundation upholds ciliary central microtubules
《Journal of Molecular Cell Biology》2024年第8期19-32,共14页Qingxia Chen Huijie Zhao Xinwen Pan Chuyu Fang Benhua Qiu Jingting Guo Xiumin Yan Xueliang Zhu 
supported by the National Natural Science Foundation of China(31991192,32230027,32270725,32100551,and 32270807);Shandong Natural Science Foundation(2022HWYQ-075).
Cilia’s back-and-forth beat pattern requires a central pair(CP)of microtubules.However,the mechanism by which the CP is upheld above the transition zone(TZ)remains unclear.Here,we showed that a rod-like substructure ...
关键词:basal plate central pair ciliary motility ependyma HYDROCEPHALUS motile cilia 
Long-term outcomes of very low birth weight infants with intraventricular hemorrhage:a nationwide population study from 2011 to 2019
《World Journal of Pediatrics》2024年第7期692-700,共9页Joonsik Park Sook-Hyun Park Yu-ra Kwon So Jin Yoon Joo Hee Lim Jung Ho Han Jeong Eun Shin Ho Seon Eun Min Soo Park Soon Min Lee 
supported by the Korea Medical Device Development Fund grant funded by the Korea government(the Ministry of Science and ICT,the Ministry of Trade,Industry and Energy,the Ministry of Health&Welfare,the Ministry of Food and Drug Safety)(Project Number:1711138055,KMMDF_PR_20200901_0057).
Background Advancements in neonatal care have increased preterm infant survival but paradoxically raised intraventricular hemorrhage(IVH)rates.This study explores IVH prevalence and long-term outcomes of very low birt...
关键词:Cerebral intraventricular hemorrhage DEVELOPMENTAL HYDROCEPHALUS MORTALITY Posthemorrhagic ventricular dilatation SURGERY 
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