supported by a grant from the Merkin Peripheral Neuropathy and Nerve Regeneration Center(to PKS);the Rutgers University Startup Fund(to PKS).
Stress granules are membraneless organelles that serve as a protective cellular response to external stressors by sequestering non-translating messenger RNAs(mRNAs)and regulating protein synthesis.Stress granules form...
supported by the National Natural Science Foundation of China,Nos.82171347,82371362;the Natural Science Foundation of Hunan Province,No.2022JJ30971;the Scientific Research Project of Hunan Provincial Health Commission of China,No.202204040024(all to GX).
A large body of evidence has highlighted the role of non-coding RNAs in neurodevelopment and neuroinflammation.This evidence has led to increasing speculation that non-coding RNAs may be involved in the pathophysiolog...
supported by National Health and Medical Research Council of Australia(APP1090890 and APP1164954);Cerebral Palsy Alliance(ERG02123);the Victorian Government’s Operational Infrastructure Support Program。
Perinatal exposure to infection/inflammation is highly associated with neural injury,and subsequent impaired cortical growth,disturbances in neuronal connectivity,and impaired neurodevelopment.However,our understandin...
supported by a grant of the M.D.-Ph.D./Medical Scientist Training Program through the Korea Health Industry Development Institute(KHIDI);funded by the Ministry of Health&Welfare,Republic of Korea(to HK);supported by National Research Foundation of Korea(NRF)grants funded by the Korean government(MSIT;Ministry of Science and ICT)(NRF2019R1A5A2026045 and NRF-2021R1F1A1061819);a grant from the Korean Health Technology R&D Project through the Korea Health Industry Development Institute(KHIDI),funded by the Ministry of Health&Welfare,Republic of Korea(HR21C1003);New Faculty Research Fund of Ajou University School of Medicine(to JYC)。
High-mobility group box 1 was first discovered in the calf thymus as a DNA-binding nuclear protein and has been widely studied in diverse fields,including neurology and neuroscience.High-mobility group box 1 in the ex...
financially supported by the National Science Fund for Distinguished Young Scholars(No.82225027);the National Key Research and Development Program(No.2021YFA1101301);the National Natural Science Foundation of China(Nos.82271419,82202702,82202351,82001308,and 82271418);Shanghai Rising-Star Program(No.22QA1408200).
Stem cell-derived spinal cord organoids(SCOs)have revolutionised the study of spinal cord development and disease mechanisms,offering a three-dimensional model that recapitulates the complexity of native tissue.This r...
supported by the grants from the National Key Project of Research and Development Program(No.2022YFC2702901);the National Natural Science Foundation of China(Nos.92168104 and 82071720);the Jiangsu Province 333 Talent Grant(No.2022-3-2-155);the Suzhou Talent Training Program(Nos.GSWS2023012 and GSWS2020057);the Jiangsu Provincial Medical Key Discipline(Laboratory)Cultivation Unit(JSDW202214);the Suzhou key clinical diseases funding(No.LCZX202109).
Biological development and genetic information transfer are governed by genetic,epigenetic,transcriptional,and posttranscriptional mechanisms.RNA methylation,the attachment of methyl(-CH3)groups to RNA molecules,is a ...
In 2013, the percentage of children ranging from 5 to 17 years who reported being diagnosed with autism surged to 1.2% from 0.1% in 1997 [1]. Alongside this increase in the incidence of autism in children, there were ...
supported by the National Natural Science Foundation of China(U21A20397,22236001,42277428);the Program for HUST Academic Frontier Youth Team(2018QYTD12).
This study aimed to investigate whether fetal growth trajectories(FGTs)could predict early childhood development,indicate intrauterine metabolic changes,and explore potential optimal and suboptimal FGTs.FGTs were deve...
supported by a grant of the Korea Health Technology R&D Project through the Korea Health Industry Development Institute(KHIDI);funded by the Ministry of Health&Welfare,Republic of Korea(grant number:HR22C1605);by the National Research Foundation of Korea(NRF)grant funded by the Korea government(MSIT)(NRF-2022R1A2C2005916).
Background Community water fluoridation is an effective public health strategy for preventing dental caries,yet.Concerns exist about potential health problems.This study explores associations between tap water fluorid...
FE65,initially identified as a binding partner of amyloid precursor protein(APP),is an adaptor protein enriched in the brain and regulated during development.FE65 belongs to the FE65 protein family.This family is comp...