supported by a grant from the European Union's Horizon 2020 research and innovation programme under the Marie Sklodowska Curie(Grant agreement No.101028929);supported by an Investigator Grant from the Medical Research Future Fund(MRF1193862);supported by an Australian Government Research Training Program Scholarship.
Background:Cardiorespiratory fitness(CRF)is a powerful health marker recommended by the American Heart Association as a clinical vital sign.Comparing the predictive validity of objectively measured CRF(the"gold standa...
supported by the Chinese National Key Technology Research and Development Program,Ministry of Science and Technology(2022YFC2504600,2021YFC2501300 and 2019YFC0840603);Beijing Municipal Science&Technology Commission(Z201100005520022,23,25-27);CAMS Innovation Fund for Medical Sciences(CIFMS)(2021-I2M-1-005 and 2022-I2M-1-004);National High Level Hospital Clinical Research Funding(2022-PUMCH-A-107,B-013,C-002,D-009).
Systemic autoimmune diseases(sAIDs)are a spectrum of diseases with multi-organ involvement that share similar clinical manifestations[1].The capacity for diagnosis and treatment of sAIDs is closely associated with the...
National Key Research and Development Project of China(2023YFC2306600);Key Program of the National Natural Science Foundation of China(82430070);Shanghai Pujiang Program(No.23PJ1410800);National Natural Science Foundation of China(82072260,32370168);Eastern Talent Plan Leading Project,Shanghai Hospital Development Center Foundation(SHDC12022121);Shanghai 2020“Science and Technology Innovation Action Plan”Medical Innovation Research Special(20Z11900900);Three-year Action Plan(2023-2025);Key Discipline Program on Public Health System Construction of Shanghai(GWVI-11.1-15);Construction of the Major Infectious Disease Medical Treatment System(GWVI-2.2).
Dear Editor,The COVID-19 pandemic,caused by the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),has resulted in millions of deaths worldwide.It poses significant challenges in the management of immunocompr...
supported by the National Natural Science Foundation of China(Grant Nos.82271111 and 81770947);New Medical Technology in Key Disciplines of Shanghai General Hospital(Grant No.0000C1801000000201050);Shanghai Science and Technology Development Foundation(Grant No.22QA1407500);Shanghai Rising Stars of Medical Talent Youth Development Program(Grant No.SHWSRS[2022-65]);Clinical Research Innovation Plan of Shanghai General Hospital(Grant No.CTCCR-2021C01).
Background To investigate the prevalence and predictors of retinal breaks reopening after vitrectomy with air tamponade in rhegmatogenous retinal detachment(RRD).Methods A retrospective cohort study was conducted in S...
Peking University First Hospital Institutional Review Board(No.2018104).
BACKGROUND With accumulating evidence showing a benefit in the renal and cardiovascular systems,diabetes guidelines recommend that patients with diabetes and chronic kidney disease(CKD)be treated with sodium-glucose c...
Background:Congenital cardiac diseases(CCD)are common congenital birth defects that require high-risk surgery.Outcomes following congenital cardiac surgery in children living in high-income countries(HIC)have been doc...
Background Data on biosimilar use in pediatric inflammatory bowel diseases(IBD)are scarce compared to the status of studies in adults,resulting in limitations in its treatment.We compared effectiveness and safety of b...
supported by grants from the National Natural Science Foundation of China(grant nos.82472554 and 82202449);the Fund for Excellent Young Scholars of Shanghai Ninth People’s Hospital,Shanghai Jiao Tong University School of Medicine(grant no.JYYQ006);the Shanghai Clinical Research Center of Plastic and Reconstructive Surgery(grant no.22MC1940300).
Fibrosis is a pathological outcome of a dysregulated repair response to injury,which can occur in any organ and have devastating effects on hundreds of millions of patients worldwide.However,challenges remain in delin...
supported by grants from the National Natural Science Foundation of China(No.82425101);Beijing Municipal Science&Technology Commission(No.Z231100004823036);Capital’s Funds for Health Improvement and Research(2022-2-2045);National Key R&D Program of China(2022YFC3602500,2022YFC3602505,2024YFC3044800,2022YFF1501500,2022YFF1501501,2022YFF1501502,2022YFF1501503,2022YFF1501504,2022YFF1501505);Outstanding Young Talents Project of Capital Medical University(A2105);Beijing High-level Public Health Technical Personnel Construction Project(Discipline leader-03-12).
Brain health as an emerging research hotspot in recent years commonly refers to a state in which people can preserve optimal brain integrity and mental and cognitive function at a given age without overt brain disease...
supported by the National Natural Science Foundation of China(62171297 and 61931013);Natural Science Foundation of Beijing Municipality(7242267);Beijing Scholars Program([2015]160).
Background:The cumulative effect of body mass index(BMI)on brain health remains ill-deffned.The effects of overweight on brain health across different age groups need clariffcation.We analyzed the effect of cumulative...