The cause of redetachment after vitrectomy with air tamponade for a cohort of 1715 patients with retinal detachment:an analysis of retinal breaks reopening  

作　　者：Chuandi Zhou Chufeng Gu Bo Li Yujie Wang Yanan Hu Xinping She Ya Shi Mingming Ma Tao Sun Qinghua Qiu Ying Fan Fenge Chen Hong Wang Kun Liu Xiaodong Sun Xun Xu Zhi Zheng 

机构地区：[1]Department of Ophthalmology,Shanghai General Hospital,Shanghai Jiao Tong University School of Medicine,No.100 Haining Road,Hongkou District,Shanghai,China [2]National Clinical Research Center for Eye Diseases,No.100 Haining Road,Hongkou District,Shanghai,China [3]Shanghai Key Laboratory of Ocular Fundus Diseases,No.100 Haining Road,Hongkou District,Shanghai,China [4]Shanghai Engineering Center for Visual Science and Photomedicine,No.100 Haining Road,Hongkou District,Shanghai,China [5]Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases,No.100 Haining Road,Hongkou District,Shanghai,China

出　　处：《Eye and Vision》2025年第1期33-40,共8页眼视光学杂志(英文)

基　　金：supported by the National Natural Science Foundation of China(Grant Nos.82271111 and 81770947);New Medical Technology in Key Disciplines of Shanghai General Hospital(Grant No.0000C1801000000201050);Shanghai Science and Technology Development Foundation(Grant No.22QA1407500);Shanghai Rising Stars of Medical Talent Youth Development Program(Grant No.SHWSRS[2022-65]);Clinical Research Innovation Plan of Shanghai General Hospital(Grant No.CTCCR-2021C01).

摘　　要：Background To investigate the prevalence and predictors of retinal breaks reopening after vitrectomy with air tamponade in rhegmatogenous retinal detachment(RRD).Methods A retrospective cohort study was conducted in Shanghai General Hospital.Chart review was performed among 1715 patients with primary RRD who received pars plana vitrectomy(PPV)with air tamponade as initial management.Patients were followed up for recurrence.The clinical features of the eyes with retinal breaks reopening were recorded.Logistic regression was constructed to investigate the predictors for breaks reopening.Results A total of 137(7.99%)patients had recurrent retinal detachment after PPV with air tamponade.The causes of surgery failure included new or missed retinal breaks(48.9%),reopening of original tears(43.8%)and proliferative vitreoretinopathy(7.3%).The median time to recurrence for the patients with breaks reopening was 18.0 days.Multivariate logistic regression indicated that the presence of retinal break(s)≥1.5 disc diameters(DD)(odds ratio[OR]:2.68,95%confdence interval[CI]:11.04–6.92,P=0.041),and shorter period for restricted activities(OR:0.94,95%CI:0.89–0.99,P=0.020)were the independent predictors for breaks reopening.Conclusions Breaks reopening is an important cause for retinal redetachment after PPV with air tamponade in primary RRD.The frst 2–4 weeks after surgery is the“risk period”for breaks reopening.Special attention should be paid for patients with retinal break(s)≥1.5 DD.A prolonged period for restricted activities is recommended.

关 键 词：Retinal redetachment Air tamponade VITRECTOMY Retinal breaks reopening Postoperative restricted activities 

分 类 号：R73[医药卫生—肿瘤]