supported by a grant from the Merkin Peripheral Neuropathy and Nerve Regeneration Center(to PKS);the Rutgers University Startup Fund(to PKS).
Stress granules are membraneless organelles that serve as a protective cellular response to external stressors by sequestering non-translating messenger RNAs(mRNAs)and regulating protein synthesis.Stress granules form...
This editorial discusses recent advancements and ongoing challenges in diabetic retinopathy,as reviewed by Morya et al in their comprehensive analysis.In their review,Morya et al discussed the pathophysiology of diabe...
This editorial discusses Thompson et al's original article,which is published in the most recent edition of the World Journal of Clinical Oncology and sheds critical light on the intertwined issues of health anxiety a...
BACKGROUND Crush syndrome refers to the traumatic rhabdomyolysis leading to a spectrum of disorders culminating in acute kidney injury.The burden of crush syndrome is high,and mortality can be as high as 20%.The signi...
Supported by the European Union-NextGenerationEU,through the National Recovery and Resilience Plan of the Republic of Bulgaria,No.BG-RRP-2.004-0008.
Type 1 diabetes(T1D)is a chronic organ-specific autoimmune disorder characterized by a progressive loss of the insulin-secreting pancreatic beta cells,which ultimately results in insulinopenia,hyperglycemia and lifelo...
Percutaneous coronary intervention(PCI),as an essential treatment for coronary artery disease,has significantly improved the prognosis of patients with large coronary artery lesions.However,some patients continue to e...
supported by the National Key R&D Program of China(2021ZD0202402 and 2021YFA1101401 to X.W.);the National Natural Science Foundation of China(82325018 and U21A20358 to X.W.,82271451 to Q.Z.);the Natural Science Foundation of Fujian Province of China(2021J02004 to X.W.);the Guangdong Basic and Applied Basic Research Foundation(2021B1515120081 to X.W.);the Fundamental Research Funds for the Chinese Central Universities(20720230070 to X.W.and Q.Z.,20720220052 to Q.Z.)。
Alzheimer's disease(AD),the leading cause of dementia,is characterized by the accumulation of amyloid plaques and neurofibrillary tangles in the brain.This condition casts a significant shadow on global health due to ...
Bile reflux gastritis (BRG) is a gastro-intestinal condition especially characterized by the reflux of bile into the stomach, further leading to mucosal inflammation along with various other clinical manifestations. D...
The article"Secondary diabetes due to different etiologies:Four case reports"by Song et al,published in the World Journal of Clinical Cases,delves into the identi-fication of rare causes of secondary diabetes and emph...
supported by grants from the National Key R&D Program of China(Nos.2023YFC3402100 and 2020YFA0509400);the Guangdong Basic and Applied Basic Research Foundation(No.2019B030302012);the National Natural Science Foundation of China(Nos.81821002,82130082,82341004,82170844,and 82270613);the 1·3·5 project for disciplines of excellence,West China Hospital,Sichuan University(No.ZYGD22007 and ZYJC21004);the Science and Technology Support Program of Sichuan Province(Nos.2023NSFSC1878,2021YFG0137,2022YFH0045,and 2022YFH0102).
Oxidative stress due to aberrant metabolism is considered as a crucial contributor to diabetes and its complications.Hyperglycemia and hyperlipemia boost excessive reactive oxygen species generation by elevated mitoch...