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Beta thalassemia syndromes:New insights
《World Journal of Clinical Cases》2025年第10期1-8,共8页Ana Dordevic Ines Mrakovcic-Sutic Sonja Pavlovic Milena Ugrin Jelena Roganovic 
Beta thalassemia(β-thalassemia)syndromes are a heterogeneous group of inherited hemoglobinopathies caused by molecular defects in the beta-globin gene that lead to the impaired synthesis of beta-globin chains of the ...
关键词：Beta thalassemia HEMOGLOBIN Molecular defects Ineffective erythropoiesis HEMOLYSIS TRANSFUSION Iron chelation Novel therapies 
Characteristics and therapeutic strategies for familial gastrointestinal stromal tumors
《World Journal of Gastrointestinal Oncology》2025年第3期13-18,共6页Yuan Liu Xiao-Feng Li 
National Natural Science Foundation of China,No.82370569;Basic and Applied Basic Research Foundation of Guangdong Province,No.2022A1515012647;the Key Program for Science and Technology Projects of Social Development in Zhuhai,No.2220004000249(to Li XF).
This editorial discusses Wang et al's article on familial gastrointestinal stromal tumors(GISTs).We read with great interest this article concerning the diagnosis,treatment,and post-treatment management of patients wi...
关键词：Gastrointestinal stromal tumors KIT mutation Platelet-derived growth factor receptor alpha mutation Wild-type gastrointestinal stromal tumor Tyrosine kinase inhibitors Familial gastrointestinal stromal tumor syndromes Molecular characteristics Targeted therapy 
Difference of the gut microbiota of premature ovarian insufficiency in two traditional Chinese syndromes
《Journal of Traditional Chinese Medicine》2025年第1期132-139,共8页WU Jiaman NING Yan TAN Liya MA Fei LIN Yanting ZHUO Yuanyuan 
Sanming Project of Medicine in Shenzhen:the First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine,Luo Songping National Famous Chinese Medicine Practitioner Female Reproductive Disorders Prevention and Treatment Team(SZZYSM202311010);Guangdong Provincial Administration of Traditional Chinese Medicine:Investigation of the Mechanism of Regulating Ren-Tong-Du Acupuncture on Ovarian Granulosa Cells in Polycystic Ovary Syndrome based on Activin A/Smads Signalling Pathway(No.20181229);Guangdong Provincial Administration of Traditional Chinese Medicine:Evaluation of the Efficacy of Menstrual Regulation and Pregnancy Promotion by Acupuncture in the Treatment of Premature Ovarian Insufficiency(No.20201294);Shenzhen Science and Innovation Commission:Investigating the Mechanism of Action of Acupuncture in Regulating the Gut Microbiome to Inhibit Apoptosis of Ovarian Granulosa Cells in Premature Ovarian Insufficiency Mice based on the Rictor/Torepamycin Target Protein C2 Pathway(No.JCYJ20210324130001004)。
PURPOSE:To investigate the differences in gut microbial characteristics between two traditional Chinese syndromes of premature ovarian insufficiency(POI).METHODS:Forty women with POI were recruited from the Department...
关键词：primary ovarian insufficiency gastrointestinal microbiome RNA ribosomal 16S gonadal steroid hormones traditional Chinese syndromes 
Importance of etiologies of secondary diabetes:How often do we think off in clinical practice?
《World Journal of Clinical Cases》2025年第5期49-51,共3页Kotha Sugunakar Reddy Arvind Kumar Morya Archana Gaur Sakthivadivel Varatharajan 
The article"Secondary diabetes due to different etiologies:Four case reports"by Song et al,published in the World Journal of Clinical Cases,delves into the identi-fication of rare causes of secondary diabetes and emph...
关键词：Diabetes mellitus ETIOLOGIES Viral infections SYNDROMES Pathophysiology Secondary diabetes mellitus Clinical practice 
Literature study on traditional Chinese medicine syndromes after renal transplantation
《World Journal of Transplantation》2025年第1期150-155,共6页Yun-Peng Guo Ling-Xue Bao Yu-Yang Wang Quan Wen Gai Hang Bo Chen 
BACKGROUND Kidney transplantation is the most effective means to treat patients with renal failure,but its postoperative problems such as rejection reactions,immunosuppressant poisoning,chronic transplant kidney nephr...
关键词：Kidney transplantation SYNDROME Literature analysis Traditional Chinese medicine Systematic review 
Study on the clinical characteristics and affecting factors of patients with different Chinese medicine syndromes of chronic heart failure
《China Medical Abstracts(Internal Medicine)》2024年第4期200-201,共2页SUN Ziyi 
Objective To explore the clinical differences among patients with chronic heart failure(CHF)with different Chinese medicine(CM)syndromes,and to identify the influencing factors of yang qi depletion and blood stasis sy...
关键词：PATIENTS CLINICAL STASIS 
Cold and Hot Syndromes in Traditional Chinese Medicine:Insights from the Perspective of Immunometabolic Homeostasis
《World Journal of Traditional Chinese Medicine》2024年第4期434-442,共9页Pan Chen Bo-Yang Wang Peng Zhang Shao Li 
sponsored by Tsinghua-Toyota Joint Research Fund;supported by the Anhui Province TraditionalChinese Medicine Science and Technology Research Project(202303a07020001);the National Natural Science Foundation of China (T2341008)
The core principle of diagnosis and treatment in traditional Chinese medicine(TCM) is the identification of different syndromes.Cold and hot syndromes are important elements in TCM theory.Identifying the biological ba...
关键词：Biological network cold/hot syndromes immunometabolism precision medicine traditional Chinese medicine 
Major Sickle Cell Syndromes in Maradi, Niger: Epidemiological, Clinical, Biological and Therapeutic Aspects
《Open Journal of Blood Diseases》2024年第4期101-108,共8页Moustapha Elhadji-Chefou Badé Malam-Abdou Amadou Djibrilla-Almoustapha Maman Brah Moustapha Djamila Mahamadou Ali Oumou Kimso Ibrahim Timi Liman Elhadji Ali Aminatou Seydou Yacouba Abdou Alzouma 
Introduction: Sickle cell disease is the most widespread genetic disorder in the world. This study aimed to investigate the epidemiological, clinical, biological, and therapeutic aspects of sickle cell anemia in Marad...
关键词：Major Sickle Cell Syndromes EPIDEMIOLOGICAL CLINICAL BIOLOGICAL Therapeutic Aspects Maradi/Niger 
Clinicopathological and molecular insights into odontogenic tumors associated with syndromes:A comprehensive review
《World Journal of Experimental Medicine》2024年第4期96-103,共8页Lauren Frenzel Schuch Felipe Martins Silveira Vanesa Pereira-Prado Estefania Sicco Deepak Pandiar Mariana Villarroel-Dorrego Ronell Bologna-Molina 
The association between genetic syndromes and odontogenic tumors encompasses several entities,reflecting the intricate interplay between genetic factors and the development of these lesions.The present study aimed to ...
关键词：Genetic syndrome Odontogenic tumors Head and neck tumors MISDIAGNOSIS Genetic mutations 
Melanocortin 4 receptor mutation in obesity
《World Journal of Experimental Medicine》2024年第4期120-128,共9页Gumpeny R Sridhar Lakshmi Gumpeny 
Obesity is increasingly prevalent worldwide,with genetic factors contributing to its development.The hypothalamic leptin-melanocortin pathway is central to the regulation of appetite and weight;leptin activates the pr...
关键词：Leptin-melanocortin pathway DOWNSTREAM G protein Cyclic AMP MUTATION Obesity syndromes Screening Setmelanotide 
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