INTERLEUKIN-17

作品数：96被引量：651H指数：12
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T helper 17 cells and interleukin-17 immunity in type 1 diabetes:From pathophysiology to targeted immunotherapies
《World Journal of Diabetes》2025年第4期48-61,共14页Georgi Vasilev Maria Kokudeva Elina Siliogka Nathalia Padilla Russka Shumnalieva David Della-Morte Camillo Ricordi Antoaneta Mihova Marco Infante Tsvetelina Velikova 
Supported by the European Union-NextGenerationEU,through the National Recovery and Resilience Plan of the Republic of Bulgaria,No.BG-RRP-2.004-0008.
Type 1 diabetes(T1D)is a chronic organ-specific autoimmune disorder characterized by a progressive loss of the insulin-secreting pancreatic beta cells,which ultimately results in insulinopenia,hyperglycemia and lifelo...
关键词：Type 1 diabetes T helper 17 cells INTERLEUKIN-17 T helper 1 cells Regulatory T cells Anti-interleukin-17 treatment Th17-targeted treatment 
Effect and mechanism of Sanqi(Radix Notoginseng) in treating periodontitis
《Journal of Traditional Chinese Medicine》2025年第1期66-75,共10页AN Yuanyuan LIU Wang LI Yanjie WANG Yanchun REN Xiaobin HE Hongbing 
Scientific Research Fund of Education Department of Yunnan Province Project:Potential Targets and Molecular Mechanisms of Sanqi(Radix Notoginseng),an Active Component of Yunnan Baiyao,in the Treatment of Periodontitis(No.2022Y204);Special Project for The Selection of High-level Scientific and Technological Talents and Innovation Teams-technical Innovation Talents Training Object Project:Technical Innovation Personnel Training Object Project(202405AD350005)。
OBJECTIVE:To investigate the effect and mechanism of Sanqi(Radix Notoginseng)in treating periodontitis.METHODS:The active components and periodontitis targets were analyzed through network pharmacology and molecular d...
关键词：Sanqi(Radix Notoginseng) PERIODONTITIS QUERCETIN INTERLEUKIN-17 inflammationSupporting information 
Interleukin-17A facilitates tumor progression via upregulating programmed death ligand-1 expression in hepatocellular carcinoma
《World Journal of Gastrointestinal Oncology》2025年第1期176-198,共23页Zhong-Xia Yang Li-Ting Zhang Xiao-Jun Liu Xue-Bin Peng Xiao-Rong Mao 
Supported by the Natural Science Foundation of Gansu Province,No.21JR7RA373 and No.24JRRA295.
BACKGROUND Hepatocellular carcinoma(HCC)is an inflammation-associated tumor with a dismal prognosis.Immunotherapy has become an important treatment strategy for HCC,as immunity is closely related to inflammation in th...
关键词：INTERLEUKIN-17A Programmed death ligand-1 Interleukin-17A receptor Small mothers against decapentaplegic 2 Hepatocellular carcinoma IMMUNOTHERAPY 
Unlocking the diagnostic potential of vascular endothelial growth factor and interleukin-17: Advancing early detection strategies for hepatocellular carcinoma
《World Journal of Gastrointestinal Surgery》2024年第11期3639-3642,共4页Shanmathi Subramanian Hamrish Kumar Rajakumar 
Tian et al investigated the diagnostic value of serum vascular endothelial growth factor(VEGF)and interleukin-17(IL-17)in primary hepatocellular carcinoma(PHC).Their retrospective study,published in the World Journal ...
关键词：Hepatocellular carcinoma Biomarkers Early detection Diagnostic accuracy Treatment strategies Therapeutic targets 
Diagnostic value of serum vascular endothelial growth factor and interleukin-17 in primary hepatocellular carcinoma被引量：1
《World Journal of Gastrointestinal Surgery》2024年第9期2934-2941,共8页Qi Tian Hui Zeng Qi-Quan Lu Hai-Ying Xie Yong Li 
BACKGROUND Despite significant advancements in the medical treatment of primary hepato-cellular carcinoma(PHC)in recent years,enhancing therapeutic effects and im-proving prognosis remain substantial challenges worldw...
关键词：Primary liver cancer Vascular endothelial growth factor INTERLEUKIN-17 Serum level Diagnostic value Cor-relation 
STAT3-Dependent Effects of Polymeric Immunoglobulin Receptor in Regulating Interleukin-17 Signaling and Preventing Autoimmune Hepatitis
《Engineering》2024年第5期209-222,共14页Ting Li Tongtong Pan Nannan Zheng Xiong Ma Xiaodong Wang Fang Yan Huimian Jiang Yuxin Wang Hongwei Lin Jing Lin Huadong Zhang Jia Huang Lingming Kong Anmin Huang Qingxiu Liu Yongping Chen Dazhi Chen 
supported by the National Natural Science Foundation of China(82070593);the Zhejiang Provincial Natural Science Foundation(LD21H030002);the Department of Science and Technology of Zhejiang Province(ZY2019008);the Youth Program of the National Natural Science Foundation of China(82200632).
One-third of patients with autoimmune hepatitis(AIH)have cirrhosis at the time of diagnosis.The relevance of these variables,although unknown,is believed to be critical in AIH because of suspected interactions between...
关键词：Autoimmune hepatitis Polymeric immunoglobulin receptor Regenerating islet-derived 3 beta Intestinal microbiota Signal transducer and activator of transcription 3 
Efficacy of interleukin-17 inhibitors on radiographic progression in psoriatic arthritis:A systematic review and meta-analysis
《Chinese Medical Journal》2024年第4期473-475,共3页Han-Lei Jiang Yu Du Qiang Tong Sheng-Ming Dai 
supported by a grant from the National Natural Science Foundation of China(No.82204722).
To the Editor:Psoriatic arthritis(PsA)is a highly heterogeneous inflammatory arthritis.It occurs in up to 30%of patients with psoriasis and can have severe impacts on peripheral joints,spine,tendon insertions,and fing...
关键词：DAMAGE ANALYSIS INHIBITORS 
Drug-induced entero-colitis due to interleukin-17 inhibitor use;capsule endoscopic findings and pathological characteristics:A case report
《World Journal of Gastroenterology》2023年第32期4912-4919,共8页Keita Saito Kiichiro Yoza Shinichiro Takeda Yoshihiro Shimoyama Ken Takeuchi 
BACKGROUND Interleukin-17(IL-17)inhibitors are known to cause exacerbation or new onset of inflammatory bowel disease upon administration.However,few reports have described characteristic endoscopic and histopathologi...
关键词：Interleukin-17 inhibitor Ixekizumab Drug-induced entero-colitis Capsule endoscopy Case report 
Role of IL-17 family cytokines in the progression of IPF from inflammation to fibrosis被引量：10
《Military Medical Research》2022年第5期618-627,共10页Yun-Juan Nie Shuo-Hua Wu Ying-Hua Xuan Gen Yan 
Natural Science Foundation of Jiangsu Province(BK20180616);the Joint Funds for the Health and Education of Fujian Province(2019-WJ-31);the Institute of Respiratory Diseases,Xiamen Medical College(HXJB-15).
Idiopathic pulmonary fibrosis(IPF)is a fatal chronic interstitial lung disease with no established treatment and is characterized by progressive scarring of the lung tissue and an irreversible decline in lung function...
关键词：Interleukin-17(IL-17)family IL-17 receptor INFLAMMATION Idiopathic pulmonary fibrosis 
Organizing Structural Principles of the Interleukin-17 Ligand-Receptor Axis
《四川生理科学杂志》2022年第7期1288-1288,共1页Steven C Wilson 
The interleukin-17 (IL-17) family of cytokines and receptors play central roles in host defense against infection, and development of inflammatory diseases1. The compositions and structures of functional IL-17 family ...
关键词：INTERLEUKIN TH2 DISEASES 
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