Unlocking the diagnostic potential of vascular endothelial growth factor and interleukin-17: Advancing early detection strategies for hepatocellular carcinoma  

作　　者：Shanmathi Subramanian Hamrish Kumar Rajakumar 

机构地区：[1]Department of General Surgery,Government Medical College,Omandurar Government Estate,Chennai 600002,Tamil Nādu,India

出　　处：《World Journal of Gastrointestinal Surgery》2024年第11期3639-3642,共4页世界胃肠外科杂志（英文）

摘　　要：Tian et al investigated the diagnostic value of serum vascular endothelial growth factor(VEGF)and interleukin-17(IL-17)in primary hepatocellular carcinoma(PHC).Their retrospective study,published in the World Journal of Gastrointestinal Surgery,revealed that the serum levels of VEGF and IL-17 are significantly elevated in PHC patients compared with healthy controls.These biomarkers are closely associated with pathological features such as tumor metastasis and clinical tumor node metastasis stage.A receiver operating characteristic analysis further confirmed the diagnostic efficacy thereof,suggesting that VEGF and IL-17 could serve as valuable tools for early detection and treatment guidance.This study underscores the potential of integrating these biomarkers into clinical practice to increase diagnostic accuracy and improve patient management in PHC.

关 键 词：Hepatocellular carcinoma Biomarkers Early detection Diagnostic accuracy Treatment strategies Therapeutic targets 

分 类 号：R735.7[医药卫生—肿瘤]