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GLIOMA: 作品数：652被引量：1460H指数：16; 导出分析报告; 相关领域：医药卫生生物学更多>>; 相关作者：黄强董军兰青章翔祁红更多>>; 相关机构：苏州大学附属第二医院首都医科大学山东大学首都医科大学附属北京天坛医院更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金国家高技术研究发展计划更多>>

Targeting capabilities of engineered extracellular vesicles for the treatment of neurological diseases: 《Neural Regeneration Research》2025年第11期3076-3094,共19页Xinyu Yang Xiangyu Gao Xiaofan Jiang Kangyi Yue Peng Luo; supported by the National Natural Science Foundation of China,Nos.82171363,82371381(to PL),82171458(to XJ);Key Research and Development Project of Shaa nxi Province,Nos.2024SF-YBXM-404(to KY)。; Recent advances in research on extracellular vesicles have significantly enhanced their potential as therapeutic agents for neurological diseases.Owing to their therapeutic properties and ability to cross the blood–b...; 关键词：Alzheimer's disease amyotrophic lateral sclerosis engineered extracellular vesicles GLIOMA ischemic stroke neurological diseases Parkinson's disease PSYCHOSIS targeted drug delivery traumatic brain injury

HMGN2 accelerates the proliferation and cell cycle progression of glioblastoma by regulating CDC20 expression: 《Genes & Diseases》2025年第3期492-507,共16页Jiacheng Zhong Shuang Shi Wen Peng Hongjuan Cui Xiaochuan Sun; Gliomas represent the most common primary malignant intracranial tumors in adults.Despite recent advances in treatment,the prognosis of patients with glioblastoma remains poor.Epigenetic abnormalities,the hallmarks of...; 关键词：CDC20 Epigenetic regulation GLIOMA Histone acetylation HMGN2

Impacts of Nutlin-3a and exercise on murine double minute 2-enriched glioma treatment: 《Neural Regeneration Research》2025年第4期1135-1152,共18页Yisheng Chen Zhongcheng Fan Zhiwen Luo Xueran Kang Renwen Wan Fangqi Li Weiwei Lin Zhihua Han Beijie Qi Jinrong Lin Yaying Sun Jiebin Huang Yuzhen Xu Shiyi Chen; supported by Project of the Health Shanghai Initiative Special Fund(Medical-Sports Integration,Creating a New Model of Exercise for Health),No.JKSHZX-2022-02(to SC).; Recent research has demonstrated the impact of physical activity on the prognosis of glioma patients,with evidence suggesting exercise may reduce mortality risks and aid neural regeneration.The role of the small ubiqu...; 关键词：exercise and SUMO-related gene signatures(ESLRS) glioblastoma management low-grade glioma natural bioactives neural regeneration physical exercise

Anoikis-related gene signature associates with the immune infiltration and predicts the prognosis of glioma patients: 《Genes & Diseases》2025年第2期117-120,共4页Jianghua Lin Junbao Wang Junmiao Zhao Xinyi Wu Leiyu Hao Xiao Tan Lixue Yang Lei-Lei Wu Yuyang Xia Xiaoling Zhang Kaijun Zhao Yu'e Liu; funded Pudong New Area Health Commission (PW2022A-28);Neuroscience Innovation and Development Research Project (YXJL-2022-00351-0183).; Glioma is the most aggressive and incurable brain tumor.1 Anoikis is programed apoptosis in which cells are detached from the cellular matrix and suspended to death.2 It plays a critical role in cancer progression.Can...; 关键词：METASTASIS Cancer PATIENTS

Integrating explainable artificial intelligence and light gradient boosting machine for glioma grading: 《Informatics and Health》2025年第1期1-8,共8页Teuku Rizky Noviandy Ghalieb Mutig Idroes Irsan Hardi; Background:Glioma grading plays a pivotal role in neuro-oncology,directly influencing treatment strategies and patient prognoses.Despite its importance,traditional histopathological analysis has drawbacks,spurring int...; 关键词：LightGBM SHAP XAI Model Interpretability Machine Learning Classification

Systemically intravenous siRNA delivery into brain with a targeting and efficient polypeptide carrier and its evaluation on anti-glioma efficacy: 《Chinese Chemical Letters》2025年第3期396-401,共6页Liqing Chen Zheming Zhang Yanhong Liu Chenfei Liu Congcong Xiao Liming Gong Mingji Jin Zhonggao Gao Wei Huang; supported by CAMS Innovation Fund for Medical Sciences(No.2021-I2M-1-026,China).; Gliomas are the most common intracranial tumors with poor survival and high mortality.Furthermore,the clinical efficacy of current drugs is still not ideal;despite the development of several therapeutic drugs over the...; 关键词：15-Amino-acid peptide GLIOMA Brain targeting Gene silencing Transvascular delivery

[^(18)F]QTFT,a nicotinate-based radiotracer targeting P2Y_(12)with satisfactory blood-brain barrier(BBB)permeability: 《Acta Pharmaceutica Sinica B》2025年第2期1202-1204,共3页Ying-Qi Song Chunquan Sheng; Recently,a novel radiotracer,[^(18)F]QTFT,synthesized by Li's group1 and published in Acta Pharmaceutica Sinica B,was identified as a PET tracer capable of specifically visualize the anti-inflammatory microglia target...; 关键词：[^(18)F]QTFT P2Y_(12)receptor Blood-brain barrier(BBB) Positron emission tomography(PET) GLIOMA

Cancer cell membrane-camouflaged biomimetic nanoparticles for enhancing chemo-radiation therapy efficacy in glioma: 《Journal of Biomedical Research》2025年第1期87-102,共16页Chunming Tang Yanling Wang Min Wu Zhiji Wang Yupeng Zhou Ya Lin Yijun Wang Huae Xu; supported by the National Natural Science Foundation of China(Grant Nos.82073308 and 82104089)。; Glioblastoma multiforme(GBM)is a highly aggressive and lethal brain tumor with limited treatment options.To improve therapeutic efficacy,we developed a novel multifunctional nanoplatform,GM@P(T/S),comprised of polymer...; 关键词：glioblastoma multiforme TEMOZOLOMIDE superparamagnetic iron oxide chemo-radiation therapy cancer cell membrane-coating

Comprehensive analysis reveals PLK3 as a promising immune target and prognostic indicator in glioma: 《Oncology Research》2025年第2期431-442,共12页TIANYUN ZHU CUNYAN ZHAO RUI GONG AO QIAN XIAOSHU WANG FANGHUI LU GANG HUO LIANGJUN QIAO SONG CHEN; supported by the Nature Science Foundation of Chongqing(Nos.cstc2016jcyjA0838 and cstc2020jcyj-msxmX0376).; Background:PLK3,which played an important role in cell cycle progression and stress response,was identified as highly expressed in various carcinomas.However,the functions,molecular characteristics,and prognostic valu...; 关键词：Polo-like kinase 3(PLK3) GLIOMA Immune response PROGNOSIS Immune microenvironment

无功能性膀胱副神经节瘤4例报道及临床病理分析: 《现代泌尿生殖肿瘤杂志》2025年第1期50-51,共2页缪俊俊孙利兵邓君鹏刘标; 膀胱副神经节瘤(paraganglioma of urinary bladder,PUB)是起源于泌尿道管壁或囊壁副神经节细胞的肿瘤,约占膀胱肿瘤的0.05%[1]。肿瘤常为单发,多位于膀胱顶部及三角区,女性略多于男性[2]。无功能性PUB临床罕见,且无特异性症状,术前诊...; 关键词：无功能性特异性症状术前诊断神经节细胞膀胱顶部膀胱肿瘤 GLIOMA 临床资料

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