SOLUBILIZATION

作品数：95被引量：243H指数：9
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相关作者：刘艳李馨儒范雅婷李眉李桂玲更多>>
相关机构：北京大学中国医学科学院防化研究院中国药科大学更多>>
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Cyclodextrin host-guest complex to facilitate sinomenine-based osteoporosis therapy
《World Journal of Stem Cells》2025年第3期139-143,共5页Meng-Qin Guo Ping Hu Zheng-Wei Huang 
Supported by Guangdong Basic and Applied Basic Research Foundation,No.2024A1515011236;General Program of Administration of Traditional Chinese Medicine of Guangdong Province,No.20241071.
Xiao et al reported on the natural product sinomenine(SIN),which is a traditional Chinese medicine for treating osteoporosis via its modulation of autophagy;however,SIN was dissolved in dimethyl sulfoxide prior to adm...
关键词：SINOMENINE CYCLODEXTRIN OSTEOPOROSIS AUTOPHAGY SOLUBILIZATION 
A supramolecular nanoprodrug for prevention of gallstone formation
《Chinese Chemical Letters》2025年第2期326-331,共6页Xiangjun Zhang Xiaodi Yang Yan Wang Zhongping Xu Sisi Yi Tao Guo Yue Liao Xiyu Tang Jianxiang Zhang Ruibing Wang 
financially supported by the National Natural Science Foundation of China(Nos.82102195,22071275 and 22271323);Natural Science Foundation of Chongqing,China(No.CSTB2022NSCQ-MSX1073);Scientific and Technological Research Program of Chongqing Municipal Education Commission(No.KJQN202100454)。
Cholelithiasis affects approximately 10%-20%of the adult population globally.And cholesterol accumulation and nucleation of cholesterol crystals are commonly recognized as the primary process in the initiation and pro...
关键词：GALLSTONE HYDROXYPROPYL-Β-CYCLODEXTRIN Hepatobiliary transport Host-guest interaction SOLUBILIZATION 
Solubilization techniques used for poorly water-soluble drugs
《Acta Pharmaceutica Sinica B》2024年第11期4683-4716,共34页Bing Xie Yaping Liu Xiaotong Li Pei Yang Wei He 
National Natural Science Foundation of China(Nos.82073782 and 82241002).
About 40%of approved drugs and nearly 90%of drug candidates are poorly water-soluble drugs.Low solubility reduces the drugability.Effectively improving the solubility and bioavailability of poorly water-soluble drugs ...
关键词：Poorly water-soluble drugs Solubilization techniques Nanocrystals COCRYSTALS Ionic liquids Polymer-based carriers Lipid-based carriers Inorganiccarriers 
Enhancing volatile fatty acids production from waste activated sludge: The role of pretreatment by N,N-bis(carboxymethyl)-L-glutamate (GLDA)
《Environmental Science and Ecotechnology》2024年第5期149-157,共9页Chang Liu Lin Li Linji Xu Tanglong Zhang Qiang He Xiaodong Xin 
supported by the National Natural Science Foundation of China(52200144,U20A20326);Key Project of Technological Innovation Application Development Plan of Chongqing City(CSTB2022TIAD-KPX0201);China Postdoctoral Science Foundation(2021M693722);Chongqing Postdoctoral Program for Innovative Talents(CQBX2021007);Technological Innovation Project of Chongqing Water&Environment Holdings Group Ltd.(KC2023-09).
N,N-bis(carboxymethyl)-L-glutamate(GLDA)is an eco-friendly chelating agent that effectively extracts multivalent metal ions from waste activated sludge(WAS)flocs,which could potentially alter their structure.However,t...
关键词：Anaerobic fermentation PRETREATMENT Resource recovery Multivalent metals SOLUBILIZATION 
Lime pretreatment of maize stover and solubilization of pretreated solids by enzymatic hydrolysis and Clostridium thermocellum fermentation
《International Journal of Agricultural and Biological Engineering》2024年第4期288-296,共9页Guanying Wang Gang Zhang Xiongjun Shao 
Lime pretreatment on maize stover was conducted with various pretreatment conditions selected by central composite design.Xylan and lignin contents in pretreated maize stover were relatively constant.Concentration of ...
关键词：central composite design lime pretreatment enzymatic hydrolysis clostridium thermocellum carbohydrate solubilization 
Magnesium-doped biochars increase soil phosphorus availability by regulating phosphorus retention,microbial solubilization and mineralization
《Biochar》2024年第1期1213-1229,共17页Muhammed Mustapha Ibrahim Huiying Lin Zhaofeng Chang Zhimin Li Asif Riaz Enqing Hou 
support was received from the Guangdong Basic and Applied Basic Research Foundation(2022B1515020014);China Postdoctoral Science Foundation(2023M743544);Fujian Forestry Science and Technology Promotion Project(2020TG17);the University-Industry Cooperation Project of Fujian Province(2021N5002).
Despite fertilization efforts,phosphorus(P)availability in soils remains a major constraint to global plant productivity.Soil incorporation of biochar could promote soil P availability but its effects remain uncertain...
关键词：Phosphorus limitation CROPLAND Functional genes Field crops Maize production 
Investigating oil solubilization into nonionic micelles by Raman multivariate curve resolution被引量：1
《Aggregate》2023年第6期146-152,共7页Ciera M.Wentworth Ryan L.Myers Paul S.Cremer Lauren D.Zarzar 
Army Research Office,Grant/Award Number:W911NF-18-1-0414;David and Lucile Packard Foundation,Grant/Award Number:2019-69664;National Science Foundation,Grant/Award Number:CHE-2004050。
Hydrophobic hydration,whereby water spontaneously structures around hydrophobic and amphiphilic molecules,plays a key role in the process of surfactant micelle formation and micellar oil solubilization.Using vibration...
关键词：hydrophobic hydration MICELLE Raman multivariate curve resolution SOLUBILIZATION 
Abiotic and biotic drivers of struvite solubilization in contrasting soils
《Pedosphere》2023年第6期828-837,共10页Antonio RUIZ-NAVARRO Manuel DELGADO-BAQUERIZO Concha CANO-DíAZ Carlos GARCíA Felipe BASTIDA 
the financial support by the Fundacion General CSIC, Spain (Programa ComFuturo);the project PID2020114942RB-I00 funded by MCIN/AEI//10.13039/5011000 11033;supported by a project from the Spanish Ministry of Science and Innovation (No. PID2020-115813RA-I00);a project of the Fondo Europeo de Desarrollo Regional (FEDER);the Consejería de Transformación Económica, Industria, Conocimiento y Universidades of the Junta de Andalucía (FEDER Andalucía 2014-2020 Objetivo temático “01— Refuerzo de la investigación, el desarrollo tecnológico y la innovación”, ANDABIOMA, No. P20_00879);supported by a postdoctoral scholarship as part of the FCT-funded project “Soil Ecosystems in the XXI Century: Drivers, Conservation and Future Scenarios” (No. FCT-PTDC/BIACBI/2340/2020) led by IPVC, Portugal。
Phosphorus(P) limitation in the coming decades calls for the utilization of alternative fertilizers in agriculture. Struvite is a promising P source, but its potential role as a fertilizer is dependent on different ph...
关键词：bacteria fungi environmental factor operational taxonomic unit phosphorus fertilizer phosphorus fraction phosphorus solubilization soil fertility soil property 
Solubilization of 2-Acetoxy-Benzencarboxylic Acid Using Beta Cyclodextrins
《Open Journal of Applied Sciences》2023年第11期1982-1995,共14页Melita Huremovic Edina Huseinovic Majda Srabovic Benjamin Catovic Emir Horozic 
2-acetoxy-benzencarboxylic acid is one of the most famous salicylate drugs today, a pharmaceutically active compound known as aspirin. It is poorly soluble in water which results in decreased bioavailability of the dr...
关键词：2-Acetoxi-Benzencarboxylic Acid Water Solubility CYCLODEXTRIN Inclusion Complexes 
Single-cell Raman and functional gene analyses reveal microbial P solubilization in agriculture waste-modified soils被引量：1
《mLife》2023年第2期190-200,共11页Hongzhe Li Jiazhi Ding Longji Zhu Fei Xu Wenjing Li Yanpo Yao Li Cui 
funded by the National Natural Science Foundation of China(42021005,22241603);the Chinese Academy of Sciences(ZDBS‐LY‐DQC027).
Application of agricultural waste such as rapeseed meal(RM)is regarded as a sustainable way to improve soil phosphorus(P)availability by direct nutrient supply and stimulation of native phosphate‐solubilizing microor...
关键词：CNP functional genes D_(2)O isotope labeling phosphate-solubilizing microorganisms single-cell Raman 
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