DYSBIOSIS

作品数:277被引量:1509H指数:20
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相关领域:医药卫生更多>>
相关作者:金月波孙晓麟栗占国李静郭建萍更多>>
相关机构:大连医科大学北京大学上海中医药大学四川省人民医院更多>>
相关期刊:更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划北京市自然科学基金中国博士后科学基金更多>>
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Positive impact of indicaxanthin from Opuntia ficusindica fruit on high-fat diet–induced neuronal damage and gut microbiota dysbiosis
《Neural Regeneration Research》2026年第1期324-332,共9页Simona Terzo Antonella Amato Pasquale Calvi Marta Giardina Domenico Nuzzo Pasquale Picone Antonio Palumbo-Piccionello Sara Amata Ilenia Concetta Giardina Alessandro Massaro Ignazio Restivo Alessandro Attanzio Luisa Tesoriere Mario Allegra Flavia Mulè 
funding from the European Union -NextGenerationEU through the Italian Ministry of University and Research under PRIN PNRR REG D.R.1718-2022– Project number PRJ-1575 INDICA。
Indicaxanthin is a betalain that is abundant in Opuntia ficus-indica orange fruit and has antioxidative and anti-inflammatory effects. Nevertheless, very little is known about the neuroprotective potential of indicaxa...
关键词:gut microbiota dysbiosis high-fat diet indicaxanthin MICROFLORA neuronal apoptosis NEURODEGENERATION NEUROINFLAMMATION obesity Opuntia ficus-indica fruit 
Fecal microbiota transplantation in allergic diseases
《World Journal of Methodology》2025年第2期83-91,共9页Ece TüsüzÖnata ÖnerÖzdemir 
Microorganisms such as bacteria,fungi,viruses,parasites living in the human intestine constitute the human intestinal microbiota.Dysbiosis refers to composi-tional and quantitative changes that negatively affect healt...
关键词:MICROBIOTA DYSBIOSIS Faecal microbiota transplantation Allergic diseases 
Characteristic dysbiosis in patients with type 2 diabetes and hyperuricemia,and the effect of empagliflozin on gut microbiota
《World Journal of Diabetes》2025年第4期74-83,共10页Xin-Ru Deng Yu-Jia Zhai Xiao-Yang Shi Sha-Sha Tang Yuan-Yuan Fang Hong-Yan Heng Ling-Yun Zhao Hui-Juan Yuan 
Supported by the National Natural Science Foundation of China,No.82270865;the Henan Provincial Key Research and Development Projects,No.231111313200;the Henan Provincial Medical Science and Technology Research Program-the Provincial and Ministerial Major Projects,No.SBGJ202301002;the Scientific and Technological Project in Henan Province,No.LHGJ20190614.
BACKGROUND Gut microbiota play a crucial role in metabolic diseases,including type 2 diabetes(T2DM)and hyperuricemia(HUA).One-third of uric acid is excreted into the intestinal tract and further metabolized by gut mic...
关键词:Type 2 diabetes HYPERURICEMIA Uric acid Empagliflozin Gut microbiota 
Long term ingestion of dietary ALEs induces metabolic disorders in mice by inducing gut dysbiosis and inhibiting AMPK/SIRT1 pathway
《Food Science and Human Wellness》2025年第2期439-449,共11页Yaya Wang Tianchang Zhang Linqing Nie Yan Zhang Junping Wang Shuo Wang 
supported by grants from the National Natural Science Foundation of China(32030083)。
Advanced lipoxidation end products(ALEs)are formed by modifying proteins with lipid oxidation products.ALEs formed in the body have been linked to diabetes and hepatic disease.However,it is not known whether ALEs form...
关键词:Dietary advanced lipoxidation end products Metabolic disorders AMPK/SITR1 signaling pathway Gut dysbiosis Intestinal barrier 
Gut microbiota plays a key role in the development of colorectal cancer
《World Journal of Gastroenterology》2025年第14期168-171,共4页Ying-Ling Liu Jie Liu 
Supported by Research Project of the Chinese Digestive Early Cancer Physicians'Joint Growth Program,No.GTCZ-2021-AH-34-0012.
This letter addresses the recently published manuscript by Darnindro et al,which investigates the diversity and composition of colonic mucosal microbiota in Indonesian patients with and without colorectal cancer(CRC)....
关键词:Colorectal cancer Gut microbiota Microbial dysbiosis Intratumoral microbiota Gut metabolites 
Analytical insights,modulation and compositional dynamics of the feline gut microbiota:a review
《Animal Diseases》2025年第1期1-16,共16页Yuejun Shi Guiqing Peng Ashenafi Assefa Gebremariam Muhammad Muazzam Iqbal Hakimeh Baghaei Daemi Muhammad Ali Khan Rizwan Ullah Donghan Wang 
funded this manuscript for the Central Universities(Grant Nos.2662023DKPY004 and 2662021DKQD005).
The gastrointestinal tract of felines is inhabited by an active and intricate population of microorganisms whose alteration creates disturbances in the immune response and can affect health and disease states.Studies ...
关键词:Analytical methods BACTERIA DISEASE DYSBIOSIS Gut microbiota 
Cross-talks between osteoporosis and gut microbiome
《World Journal of Orthopedics》2025年第3期11-27,共17页Shiva Shankar Jha Naveen Jeyaraman Madhan Jeyaraman Swaminathan Ramasubramanian Sathish Muthu Gabriel Silva Santos Lucas Furtado da Fonseca JoséFábio Lana 
The gut microbiome comprises a vast community of microbes inhabiting the human alimentary canal,playing a crucial role in various physiological functions.These microbes generally live in harmony with the host;however,...
关键词:MICROBIOME DYSBIOSIS OSTEOPOROSIS PREBIOTICS Probiotics Inflammation BILE Vitamin D Calcium 
Unlocking the secrets of the human gut microbiota:Comprehensive review on its role in different diseases
《World Journal of Gastroenterology》2025年第5期13-31,共19页Jibon Kumar Paul Mahir Azmal ANM Shah Newaz Been Haque Meghla Meem Omar Faruk Talukder Ajit Ghosh 
The human gut microbiota,a complex and diverse community of microorganisms,plays a crucial role in maintaining overall health by influencing various physio-logical processes,including digestion,immune function,and dis...
关键词:Gut microbiota CANCER DIABETICS Autoimmune disease DYSBIOSIS 
FLZ attenuates Parkinson's disease pathological damage by increasing glycoursodeoxycholic acid production via down-regulating Clostridium innocuum
《Acta Pharmaceutica Sinica B》2025年第2期973-990,共18页Meiyu Shang Jingwen Ning Caixia Zang Jingwei Ma Yang Yang Yueqi Jiang Qiuzhu Chen Yirong Dong Jinrong Wang Fangfang Li Xiuqi Bao Dan Zhang 
supported by The National Key Research and Development Program of China(grant No.2023YFC3502800);the CAMS Innovation Found for Medical Sciences(No.2022-I2M-2-001,China).
Increasing evidence shows that the early lesions of Parkinson's disease(PD)originate from gut,and correction of microbiota dysbiosis is a promising therapy for PD.FLZ is a neuroprotective agent on PD,which has been va...
关键词:Parkinson's disease FLZ Glycoursodeoxycholic acid Clostridium innocuum Gut-brain axis Microbiota dysbiosis Microbial metabolites NEUROINFLAMMATION 
Acrylamide drives amidase-mediated gut dysbiosis to aggravate colitis
《Science Bulletin》2025年第2期157-161,共5页Daotong Li Yinghua Luo Huimin Fan Li Dong Xiaoying Zhang Yu Feng Meiling Tian Shuqing Zhang Wenjing Chen Lujia Zhang Jianwei Gao Xiangning Ma Xiaofei Wang Chen Ma Ruimao Zheng Xiaosong Hu Jinfeng Wang Fang Chen 
supported by the National Natural Science Foundation of China(32230081,32371511,and 32001677)。
Inflammatory bowel diseases(IBDs)are chronic intestinal inflammatory disorders that have emerged as a global public health challenge[1].Increased availability and consumption of processed foods is considered as a cruc...
关键词:diseases prevalence clarified 
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