HYPERURICEMIA

作品数:154被引量:430H指数:10
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相关领域:医药卫生更多>>
相关作者:叶晓兰狄亚珍沈雅庭王力刘彦波更多>>
相关机构:宁波市妇女儿童医院昆明医科大学浙江省人民医院浙江省宁波市妇女儿童医院更多>>
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相关基金:国家自然科学基金广东省自然科学基金国家重点基础研究发展计划北京市自然科学基金更多>>
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Lactic acid bacteria act as potent interventions in improving hyperuricemia:a review
《Food Science and Human Wellness》2025年第4期1212-1223,共12页Qingling Wu Xiaodong Pei Tiantian Gao Xiaoling Liu Chenghua Wang 
funded by National Natural Science Foundation of China(32360564);the Natural Science and Technology Innovation Development Multiplication Plan of Guangxi University(2022BZRC010)。
Hyperuricemia(HUA)is characterized by elevated levels of uric acid(UA)in the bloodstream,resulting from either excessive production or insufficient excretion of UA within the body.If left untreated,progressive or pers...
关键词:HYPERURICEMIA GOUT Lactic acid bacteria Uric acid-lowering mechanism 
Metabolic mechanism of dietary factors and effect of dietary types associated with hyperuricemia:a review
《Food Science and Human Wellness》2025年第3期835-849,共15页Kaina Qiao Xuewei Zhou Lili Zhang Wangang Zhang Baoguo Sun Yuyu Zhang 
supported by the National Natural Science Foundation of China(No.32122069);Beijing Outstanding Young Scientist Program(No.BJJWZYJH01201910011025);China Postdoctoral Science Foundation(No.2023M730134)。
Globally,hyperuricemia is a growing health,social,and economic problem which could cause gout,chronic kidney diseases and other diseases.There are increasing evidences that a sensible diet makes sense to reduce the ri...
关键词:PURINE Metabolic mechanism Dietary types HYPERURICEMIA Personalized diet 
Dual benefits of sodium-glucose cotransporter 2 inhibitors in metabolic diseases: Diabetes control and gout management
《World Journal of Clinical Cases》2025年第14期61-64,共4页Xiao-Peng Fu 
The study by Lin et al delves into the clinical impact of dapagliflozin,a repre-sentative sodium-glucose cotransporter 2(SGLT2)inhibitor,on chronic heart failure complicated by hyperuricemia.This investigation highlig...
关键词:Sodium-glucose cotransporter 2 inhibitors HYPERURICEMIA GOUT Uric acid reduction Chronic heart failure 
Characteristic dysbiosis in patients with type 2 diabetes and hyperuricemia,and the effect of empagliflozin on gut microbiota
《World Journal of Diabetes》2025年第4期74-83,共10页Xin-Ru Deng Yu-Jia Zhai Xiao-Yang Shi Sha-Sha Tang Yuan-Yuan Fang Hong-Yan Heng Ling-Yun Zhao Hui-Juan Yuan 
Supported by the National Natural Science Foundation of China,No.82270865;the Henan Provincial Key Research and Development Projects,No.231111313200;the Henan Provincial Medical Science and Technology Research Program-the Provincial and Ministerial Major Projects,No.SBGJ202301002;the Scientific and Technological Project in Henan Province,No.LHGJ20190614.
BACKGROUND Gut microbiota play a crucial role in metabolic diseases,including type 2 diabetes(T2DM)and hyperuricemia(HUA).One-third of uric acid is excreted into the intestinal tract and further metabolized by gut mic...
关键词:Type 2 diabetes HYPERURICEMIA Uric acid Empagliflozin Gut microbiota 
Associations of polycyclic aromatic hydrocarbons exposure with serum uric acid and hyperuricemia in US adults:The role of systemic inflammation
《Journal of Environmental Sciences》2025年第4期412-421,共10页Yang Liu Xuejie Ding Linling Yu Da Shi Ruyi Liang Wei Liu Xuezan Huang Xiuyu Cao Min Zhou Weihong Chen 
supported by the Key Program of National Natural Science Foundation of China(No.82241088);the Natural Science Foundation of Hubei Province(No.2022CFB813).
The associations of polycyclic aromatic hydrocarbon(PAH)exposure with serum uric acid(SUA)or hyperuricemia have been rarely assessed.We aimed to investigate the relationships between urinary PAH metabolites and SUA or...
关键词:Polycyclic aromatic hydrocarbon Serum uric acid HYPERURICEMIA C-reactive protein General population 
Modulation of gut microbiota and serum metabolome by Apostichopus japonicus derived oligopeptide in high-fructose diet-induced hyperuricemia in mice
《Food Science and Human Wellness》2025年第1期161-174,共14页Jun Zhou Ziyan Wang Zhixuan Zhang Jiaojiao Han Ying Feng Jing Zhang Zhen Zhang Ye Li Tinghong Ming Chenyang Lu Rixin Wang Xiurong Su 
sponsored by the One Health Interdisciplinary Research Project,Ningbo University,Open Fund of Key Laboratory of Aquacultural Biotechnology Ministry of Education in Ningbo University,and K.C.Wong Magna Fund of Ningbo University;the National Natural Science Foundation China(32270115);National Key R&D Program of China(2018YFD0901102);Fundamental Research Funds for the Provincial Universities of Zhejiang(SJLY2021015)。
Fructose consumption has risen dramatically in recent decades due to the use of sucrose and high fructose corn syrup in beverages and processed foods,contributing to rising rates of hyperuricemia.The purpose of this e...
关键词:FRUCTOSE HYPERURICAEMIA OLIGOPEPTIDE Gut microbiota Serum metabolomics 
Deciphering the molecular mechanisms of Simiaowan in the treatment of hyperuricemia: in vivo and in silico approaches
《Traditional Medicine Research》2025年第2期37-54,共18页Yong-Chang Zeng Jun-Hong Wu Dan-Dan Xu Kang He Chang-Qing Liu Li-Fei Song Zheng-Zhi Wu Qian-Qian Jiang Shao-Yu Liang 
supported by Natural Science Foundation of Guangdong Province(2021A1515010978 and 2021A1515012474);Basic research project of Shenzhen Science and Innovation Commission(JCYJ20210324121610029);Guangdong Provincial Key Areas Research and Development Program project Lingnan TCM Modernization(2020B1111120003).
Background:Simiaowan(SMW),a well-known traditional Chinese medicine,has been employed to treat hyperuricemia(HUA)and gout for centuries.However,the bioactive components and underlying mechanisms have not been elucidat...
关键词:HYPERURICEMIA network pharmacology serum pharmacochemistry Simiaowan UPLC-Q-Exactive-MS/MS 
Enhancing spleen function for effective hyperuricemia treatment
《Journal of Chinese Pharmaceutical Sciences》2025年第2期99-108,共10页Qian Deng Zining Peng Fanyu Meng Weitian Yan Nian Liu Jiangyun Peng 
National Natural Science Foundations of China(Grant No.81960863);the Education Department of Yunnan Province(Grant No.2023Y0463 and 2024Y380);Yunnan Clinical Research Center for rheumatism in Traditional Chinese Medicine(Grant No.202405AJ310004).
Hyperuricemia(HUA)is a metabolic disorder characterized by elevated levels of uric acid in the blood,resulting from either increased production or decreased excretion of uric acid.This condition has reached epidemic p...
关键词:Strengthening the spleen HYPERURICEMIA DIAGNOSIS TREATMENT 
Efficacy and safety of Liqingtong granules in the treatment of hyperuricemia:A randomized double-blind placebo-controlled pilot clinical trial
《Journal of Traditional Chinese Medical Sciences》2024年第4期415-422,共8页Jinlian Liu Yi Yang Meiyu Lv Wenting Fei Songrui Di Mei Luo Qing Lin Chun Wang Linyuan Wang Jianjun Zhang 
funded by the National Key Research and Development Plan of the Traditional Chinese Medicine Modernization Research Key Project(2018YFC1706800).
Objective:To investigate the efficacy and safety of Liqingtong(LQT)granules in patients with dampness-heat hyperuricemia.Methods:A randomized,double-blind,placebo-controlled pilot trial was conducted at the 983rd Hos-...
关键词:Traditional Chinese medicine HYPERURICEMIA Liqingtong granules Dampness-heat pattern Clinical trial 
Gut microbiota participates and remodels host metabolism:From treating patients to treating their gut flora
《World Journal of Gastroenterology》2024年第45期4839-4843,共5页Shuang Han Rui-Hua Li Peng Gao 
In this editorial,we comment on Liu et al’s article published in the recent issue of the World Journal of Gastroenterology.Biochemically and pathologically,Liu et al proved that the urate-lowering activity of leech t...
关键词:Gut microbiota METABOLISM Metabolomics HYPERURICEMIA PEPTIDES 
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