funded by National Natural Science Foundation of China(32360564);the Natural Science and Technology Innovation Development Multiplication Plan of Guangxi University(2022BZRC010)。
Hyperuricemia(HUA)is characterized by elevated levels of uric acid(UA)in the bloodstream,resulting from either excessive production or insufficient excretion of UA within the body.If left untreated,progressive or pers...
supported by the National Natural Science Foundation of China(No.32122069);Beijing Outstanding Young Scientist Program(No.BJJWZYJH01201910011025);China Postdoctoral Science Foundation(No.2023M730134)。
Globally,hyperuricemia is a growing health,social,and economic problem which could cause gout,chronic kidney diseases and other diseases.There are increasing evidences that a sensible diet makes sense to reduce the ri...
The study by Lin et al delves into the clinical impact of dapagliflozin,a repre-sentative sodium-glucose cotransporter 2(SGLT2)inhibitor,on chronic heart failure complicated by hyperuricemia.This investigation highlig...
Supported by the National Natural Science Foundation of China,No.82270865;the Henan Provincial Key Research and Development Projects,No.231111313200;the Henan Provincial Medical Science and Technology Research Program-the Provincial and Ministerial Major Projects,No.SBGJ202301002;the Scientific and Technological Project in Henan Province,No.LHGJ20190614.
BACKGROUND Gut microbiota play a crucial role in metabolic diseases,including type 2 diabetes(T2DM)and hyperuricemia(HUA).One-third of uric acid is excreted into the intestinal tract and further metabolized by gut mic...
supported by the Key Program of National Natural Science Foundation of China(No.82241088);the Natural Science Foundation of Hubei Province(No.2022CFB813).
The associations of polycyclic aromatic hydrocarbon(PAH)exposure with serum uric acid(SUA)or hyperuricemia have been rarely assessed.We aimed to investigate the relationships between urinary PAH metabolites and SUA or...
sponsored by the One Health Interdisciplinary Research Project,Ningbo University,Open Fund of Key Laboratory of Aquacultural Biotechnology Ministry of Education in Ningbo University,and K.C.Wong Magna Fund of Ningbo University;the National Natural Science Foundation China(32270115);National Key R&D Program of China(2018YFD0901102);Fundamental Research Funds for the Provincial Universities of Zhejiang(SJLY2021015)。
Fructose consumption has risen dramatically in recent decades due to the use of sucrose and high fructose corn syrup in beverages and processed foods,contributing to rising rates of hyperuricemia.The purpose of this e...
supported by Natural Science Foundation of Guangdong Province(2021A1515010978 and 2021A1515012474);Basic research project of Shenzhen Science and Innovation Commission(JCYJ20210324121610029);Guangdong Provincial Key Areas Research and Development Program project Lingnan TCM Modernization(2020B1111120003).
Background:Simiaowan(SMW),a well-known traditional Chinese medicine,has been employed to treat hyperuricemia(HUA)and gout for centuries.However,the bioactive components and underlying mechanisms have not been elucidat...
National Natural Science Foundations of China(Grant No.81960863);the Education Department of Yunnan Province(Grant No.2023Y0463 and 2024Y380);Yunnan Clinical Research Center for rheumatism in Traditional Chinese Medicine(Grant No.202405AJ310004).
Hyperuricemia(HUA)is a metabolic disorder characterized by elevated levels of uric acid in the blood,resulting from either increased production or decreased excretion of uric acid.This condition has reached epidemic p...
funded by the National Key Research and Development Plan of the Traditional Chinese Medicine Modernization Research Key Project(2018YFC1706800).
Objective:To investigate the efficacy and safety of Liqingtong(LQT)granules in patients with dampness-heat hyperuricemia.Methods:A randomized,double-blind,placebo-controlled pilot trial was conducted at the 983rd Hos-...
In this editorial,we comment on Liu et al’s article published in the recent issue of the World Journal of Gastroenterology.Biochemically and pathologically,Liu et al proved that the urate-lowering activity of leech t...