GOUT

作品数:140被引量:290H指数:9
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相关领域:医药卫生更多>>
相关作者:赵瑛王斌陈芳孟建国唐柳更多>>
相关机构:北京联合大学北京中医药大学陕西中医药大学南通医学院附属医院更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划广东省自然科学基金王宽诚敎育基金更多>>
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Lactic acid bacteria act as potent interventions in improving hyperuricemia:a review
《Food Science and Human Wellness》2025年第4期1212-1223,共12页Qingling Wu Xiaodong Pei Tiantian Gao Xiaoling Liu Chenghua Wang 
funded by National Natural Science Foundation of China(32360564);the Natural Science and Technology Innovation Development Multiplication Plan of Guangxi University(2022BZRC010)。
Hyperuricemia(HUA)is characterized by elevated levels of uric acid(UA)in the bloodstream,resulting from either excessive production or insufficient excretion of UA within the body.If left untreated,progressive or pers...
关键词:HYPERURICEMIA GOUT Lactic acid bacteria Uric acid-lowering mechanism 
Dual benefits of sodium-glucose cotransporter 2 inhibitors in metabolic diseases: Diabetes control and gout management
《World Journal of Clinical Cases》2025年第14期61-64,共4页Xiao-Peng Fu 
The study by Lin et al delves into the clinical impact of dapagliflozin,a repre-sentative sodium-glucose cotransporter 2(SGLT2)inhibitor,on chronic heart failure complicated by hyperuricemia.This investigation highlig...
关键词:Sodium-glucose cotransporter 2 inhibitors HYPERURICEMIA GOUT Uric acid reduction Chronic heart failure 
Hypocrellin A from an ethnic medicinal fungus protects against NLRP3-driven gout in mice by suppressing inflammasome activation
《Acta Pharmacologica Sinica》2025年第4期1016-1029,共14页Le-jin Yan Shuang Qi Chao Wu Rui Jin Chen Hu Ao-li Wang Bei-lei Wang Hong-wei Yu Li Wang Jing Liu Zi-ping Qi Wen-chao Wang Qing-song Liu 
supported by the National Natural Science Foundation of China(Grant Nos.82373715,32171479,82304784);the Major Science and Technology Project of Anhui Province(Grant No.202303a07020007);the CASHIPS Director’s Found(Grant No.BJPY2022A02).
Abnormal activation of NLRP3 inflammasome causes the progression of gout,and no small-molecule inhibitor of NLRP3 has been approved yet for clinical use.In this study we established a nigericin-induced inflammasome ac...
关键词:gouty arthritis hypocrellin A ethnic medicine NLRP3 inflammasome NEK7 NACHT domain 
The Molecular Mechanism of Weilingxian and Guizhi in the Treatment of Gout was Studied Based on Network Pharmacology
《Journal of Clinical and Nursing Research》2025年第2期13-20,共8页Dongrong Mo Guilu Luo Fang Kong Zhenwei Liu 
Objective:To explore the mechanism of action of"Weilingxian-Guizhi"two drugs in the treatment of gout.Method:First obtain the 15 chemical components contained in the"Weilingxian-Guizhi"drug,predict its target points t...
关键词:Weilingxian Guizhi GOUT Network pharmacology TARGET Signal pathway 
Self-management behavior preferences and influencing factors in Chinese patients with recurrent gout:A qualitative study
《International Journal of Nursing Sciences》2024年第5期544-552,共9页Xinyi Hao Aiping Wang Hao Huang Yue Sun Yingying Duan Shanwen Sun 
Objectives:This study aimed to explore the preferences and influencing factors of self-management behaviors in patients with recurrent gout and provide a theoretical basis for developing targeted strategies to improve...
关键词:BEHAVIOR GOUT KJ method Qualitative research RECURRENT SELF-MANAGEMENT 
Historical pearls of the European medical school related to the acute articular rheumatism from the Renaissance to the 20^(th) century
《History & Philosophy of Medicine》2024年第4期24-28,共5页Evangelia Mourellou Gregory Tsoucalas 
Acute articular rheumatism(AAR)primarily affects children aged 5 to 15,causing fever and non-suppurative arthritis,and can lead to severe heart problems such as mitral stenosis and aortic insufficiency.Descriptions of...
关键词:Jean-Baptiste Bouillaud podagral GOUT STREPTOCOCCUS heart lesion 
International clinical practice guideline of Chinese medicine - Gout (SCM73–2024)
《Clinical Traditional Medicine and Pharmacology》2024年第4期1-8,共8页Xuanlin Li Lin Huang Zhijun Xie Yaolong Chen Chengping Wen 
National Key R&D Programme Project(2022YFC3501200);Zhejiang Provincial Science and Technology Programme Project(2023C03040);State Administration of Traditional Chinese Medicine Science and Technology Department-Zhejiang Provincial Administration of Traditional Chinese Medicine Joint Project(GZY-ZJ-KJ-23009).
Background:Gout is a metabolic rheumatic disease that seriously endangers human health,with a relatively high prevalence and disability rate worldwide.Current international clinical practice guidelines provide recomme...
关键词:GOUT RECOMMENDATIONS Chinese medicine GUIDELINE 
Virtual screening and directional preparation of xanthine oxidase inhibitory peptides derived from hemp seed protein
《Food Science and Human Wellness》2024年第6期3652-3660,共9页Xiaoni Huang Jiajun Liao Ping Shi Xiaodong Pei Chenghua Wang 
funded by National Natural Science Foundation of China(21868003);Bama County Program for Talents in Science and Technology(BaRenKe20210045).
The traditional nutritional and medical hemp(Cannabis sativa L.)seed protein were explored for the discovery and directional preparation of new xanthine oxidase inhibitory(XOI)peptides by structure-based virtual scree...
关键词:Hemp seed protein Anti-gout Bioactive peptide Virtual screening PROTEOLYSIS 
Roles of traditional Chinese medicine extracts in hyperuricemia and gout treatment:Mechanisms and clinical applications
《World Journal of Gastroenterology》2024年第47期5076-5080,共5页Yan-Bo Wang Chang-Zhong Jin 
Supported by Zhejiang Province Leading Geese Program,No.2024C03218;Research Project of Jinan Microecological Biomedicine Shandong Laboratory,No.JNL-2023010Q.
In this manuscript,we comment on the article by Liu et al published in the recent issue of the journal.Hyperuricemia(HUA)has become the second most common metabolic disease after type 2 diabetes mellitus and is the mo...
关键词:HYPERURICEMIA GOUT Traditional Chinese medicine Gut microbiota Multitarget Uric acid metabolic homeostasis 
Rare manifestation of gout:Gouty tophi in unusual locations
《Rheumatology & Autoimmunity》2024年第4期267-268,共2页Yinzi Chen Xiangyu Wang Nan Wang Guoyun Li Ruomei Cui Jian Xu Yulong Guo Shuang Liu 
supported by grants from the National Natural Science Foundation of China(No.32270947);Yunnan Applied Basic Research Projects,Kunming Medical University Union Special Fund(No.202301AY070001-043,No.202301AY070001-159);The Ten Thousand Scientists Program of Yunnan Province(No.YN-WR-MY-2018-040,No.YNWR-QNBJ-2018-152);535 Talent Project of First Affiliated Hospital of Kunming Medical University(No.2022535Q01);Yunnan Clinical Center for Skin Immune Diseases(No.ZX2019-03-02).
A 32-year-old male patient with gout presented to First Affiliated Hospital of Kunming Medical University for the first time,complaining of intermittent knee and ankle pain for the past 4 years.The highest level of hi...
关键词:Medical pain UNUSUAL 
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