Neurodegenerative diseases are often studied in isolation due to the vast differences in their underlying causes,the diversity in neuron types affected,and the variations in their clinical symptoms.However,there are c...
The pathophysiology of ischemic stroke is complex and multifactorial,involving various forms of cell death such as apoptosis,autophagy,and necrosis.A recent study suggests that oxidative and inflammatory stress can in...
supported by the National Natural Science Foundation of China,Nos.82001178(to LW),81901129(to LH),82001175(to FX);Shanghai Sailing Program,No.20YF1439200(to LW);the Natural Science Foundation of Shanghai,China,No.23ZR1450800(to LH);and the Fundamental Research Funds for the Central Universities,No.YG2023LC15(to ZX)。
Protein arginine methyltransferase-6 participates in a range of biological functions,particularly RNA processing,transcription,chromatin remodeling,and endosomal trafficking.However,it remains unclear whether protein ...
This editorial provides insights into the pivotal role of checkpoint kinase 1(CHEK1)as both a biomarker and therapeutic target in colorectal cancer(CRC),based on findings from a recent study by Pang et al.Using single...
Supported in part by the National Natural Science Foundation of China(11925506,12475090).
We investigate the soft behavior of the tree-level Rutherford scattering process.We consider two types of Rutherford scattering processes:One in which a low-energy massless point-like projectile(say,a spin-1/2 or spin...
Supported by Yunnan Province Academician(Expert)Workstation Project,No.202305AF150097;the Basic Research Program of Yunnan Province(Kunming Medical University Joint Special Project),No.202101AY070001-276;the National Natural Science Foundation of China,No.82160159;the Key Project Program of Yunnan Province(Kunming Medical University Joint Special Project),No.202301AY070001-013;the Major Science and Technology Project of Yunnan Province,No.202202AA100004;the Double First-class University Construction Project of Yunnan University,No.CY22624106.
BACKGROUND Continuous glucose monitoring(CGM)metrics,such as time in range(TIR)and glycemic risk index(GRI),have been linked to various diabetes-related complications,including diabetic foot(DF).AIM To investigate the...
supported by National Natural Science Foundation of China (No.11275136)。
The discharge and plasma characteristics of Ag magnetron sputtering discharge operated near the electron series resonance(ESR)oscillation,which was excited using the driving frequency of 27.12 MHz,was investigated.The...
financially supported by Central Government Guided Local Science and Technology Development Fund Project(guikeZY22096017);Natural Science Foundation of Guangxi Province(2024GXNSFDA010036);National Natural Science Foundation of China(22164014,U23A2089)。
A highly sensitive electrochemical aptasensor was developed for the detection of kanamycin,employing a DNA signal amplification strategy that combines RecJf exonuclease-assisted target recycling with a hybridization c...
Zhongheng Zhang received funding from the National Natural Science Foundation of China(82272180,82472243);the China National Key Research and Development Program(2023YFC3603104);the Huadong Medicine Joint Funds of the Zhejiang Provincial Natural Science Foundation of China(LHDMD24H150001);the China National Key Research and Development Program(2022YFC2504500);a collaborative scientific project co-established by the Science and Technology Department of the National Administration of Traditional Chinese Medicine and the Zhejiang Provincial Administration of Traditional Chinese Medicine(GZY-ZJKJ-24082);the General Health Science and Technology Program of Zhejiang Province(2024KY1099);Project of Zhejiang University Longquan Innovation Center(ZJDXLQCXZCJBGS2024016);Hongying Ni received funding from Jinhua Science and Technology Planning Project(2024-3-047).
Objective:To develop and demonstrate a comprehensive methodological framework for target trial emulation(TTE)implementation via post-laparoscopic septic shock fluid management as a clinical case study.Methods:We desig...
Fall Armyworms (FAW) Spodoptera frugiperda, particularly in maize crops, is a major agricultural pest. Current control methods rely heavily on chemical pesticides, which are costly and harmful to non-target organisms....