TARGET

作品数:1580被引量:2830H指数:18
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相关领域:医药卫生更多>>
相关作者:郭洪艳陈虹江东薛明旭胡郁更多>>
相关机构:上海交通大学北京理工大学吉林大学北京航空航天大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划国家教育部博士点基金更多>>
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LPAR3:a shared target for neurodegenerative diseases?
《Neural Regeneration Research》2025年第12期3527-3528,共2页Susan Acton Laurent Chesnel 
Neurodegenerative diseases are often studied in isolation due to the vast differences in their underlying causes,the diversity in neuron types affected,and the variations in their clinical symptoms.However,there are c...
关键词:DISEASES DEGENERATIVE 
Iron-handling solute carrier SLC22A17 as a blood-brain barrier target after stroke
《Neural Regeneration Research》2025年第11期3207-3208,共2页Xueqi Ren Wenlu Li 
The pathophysiology of ischemic stroke is complex and multifactorial,involving various forms of cell death such as apoptosis,autophagy,and necrosis.A recent study suggests that oxidative and inflammatory stress can in...
关键词:DEATH specialized BARRIER 
Protein arginine methyltransferase-6 regulates heterogeneous nuclear ribonucleoprotein-F expression and is a potential target for the treatment of neuropathic pain
《Neural Regeneration Research》2025年第9期2682-2696,共15页Xiaoyu Zhang Yuqi Liu Fangxia Xu Chengcheng Zhou Kaimei Lu Bin Fang Lijuan Wang Lina Huang Zifeng Xu 
supported by the National Natural Science Foundation of China,Nos.82001178(to LW),81901129(to LH),82001175(to FX);Shanghai Sailing Program,No.20YF1439200(to LW);the Natural Science Foundation of Shanghai,China,No.23ZR1450800(to LH);and the Fundamental Research Funds for the Central Universities,No.YG2023LC15(to ZX)。
Protein arginine methyltransferase-6 participates in a range of biological functions,particularly RNA processing,transcription,chromatin remodeling,and endosomal trafficking.However,it remains unclear whether protein ...
关键词:dorsal root ganglion heterogeneous nuclear ribonucleoprotein F neuropathic pain protein arginine methyltransferase-6 sensory neurons 
Checkpoint kinase 1 as a promising target in colorectal cancer management
《World Journal of Clinical Oncology》2025年第4期6-8,共3页Wenxue Ma Natalia Baran 
This editorial provides insights into the pivotal role of checkpoint kinase 1(CHEK1)as both a biomarker and therapeutic target in colorectal cancer(CRC),based on findings from a recent study by Pang et al.Using single...
关键词:Colorectal cancer Checkpoint kinase 1 BIOMARKER Therapeutic target Single-cell RNA sequencing Nitidine chloride 
Soft pattern of Rutherford scattering from heavy target mass expansion
《Chinese Physics C》2025年第3期17-27,共11页Yu Jia Jia-Yue Zhang 
Supported in part by the National Natural Science Foundation of China(11925506,12475090).
We investigate the soft behavior of the tree-level Rutherford scattering process.We consider two types of Rutherford scattering processes:One in which a low-energy massless point-like projectile(say,a spin-1/2 or spin...
关键词:Rutherford scattering nucleus structure heavy quark effective theory NRQED 
Correlation between key indicators of continuous glucose monitoring and the risk of diabetic foot
《World Journal of Diabetes》2025年第3期30-43,共14页Xin-Qian Geng Shun-Fang Chen Fei-Ying Wang Hui-Jun Yang Yun-Li Zhao Zhang-Rong Xu Ying Yang 
Supported by Yunnan Province Academician(Expert)Workstation Project,No.202305AF150097;the Basic Research Program of Yunnan Province(Kunming Medical University Joint Special Project),No.202101AY070001-276;the National Natural Science Foundation of China,No.82160159;the Key Project Program of Yunnan Province(Kunming Medical University Joint Special Project),No.202301AY070001-013;the Major Science and Technology Project of Yunnan Province,No.202202AA100004;the Double First-class University Construction Project of Yunnan University,No.CY22624106.
BACKGROUND Continuous glucose monitoring(CGM)metrics,such as time in range(TIR)and glycemic risk index(GRI),have been linked to various diabetes-related complications,including diabetic foot(DF).AIM To investigate the...
关键词:Continuous glucose monitoring Time in range Glycemia risk index Diabetic foot Continuous glucose monitoring target achievement 
Characteristics of radio-frequency magnetron sputtering with Ag target operated near the electron series resonance oscillation
《Plasma Science and Technology》2025年第3期111-117,共7页Chao YE 
supported by National Natural Science Foundation of China (No.11275136)。
The discharge and plasma characteristics of Ag magnetron sputtering discharge operated near the electron series resonance(ESR)oscillation,which was excited using the driving frequency of 27.12 MHz,was investigated.The...
关键词:electron series resonance magnetron sputtering radio-frequency discharge 
A Highly Sensitive Electrochemical Aptasensor for Kanamycin:Leveraging RecJf Exonuclease-Assisted Target Recycling and Hybridization Chain Reaction Signal Amplification
《Journal of Analysis and Testing》2025年第1期96-108,共13页Qi Xiao Dongyou Zhang Mingli Yang Shuai Liu Yi Fang Shan Huang 
financially supported by Central Government Guided Local Science and Technology Development Fund Project(guikeZY22096017);Natural Science Foundation of Guangxi Province(2024GXNSFDA010036);National Natural Science Foundation of China(22164014,U23A2089)。
A highly sensitive electrochemical aptasensor was developed for the detection of kanamycin,employing a DNA signal amplification strategy that combines RecJf exonuclease-assisted target recycling with a hybridization c...
关键词:KANAMYCIN Target recycling Hybridization chain reaction Signal amplification Long dsDNA nanostructures 
A comprehensive step-by-step approach for the implementation of target trial emulation:Evaluating fluid resuscitation strategies in post-laparoscopic septic shock as an example
《Laparoscopic, Endoscopic and Robotic Surgery》2025年第1期28-44,共17页Jie Yang Lihui Wang Lin Chen Pengmin Zhou Suibi Yang Hongjie Shen Lifeng Xing Pengpeng Chen Yuetian Yu Hongying Ni Zhongheng Zhang 
Zhongheng Zhang received funding from the National Natural Science Foundation of China(82272180,82472243);the China National Key Research and Development Program(2023YFC3603104);the Huadong Medicine Joint Funds of the Zhejiang Provincial Natural Science Foundation of China(LHDMD24H150001);the China National Key Research and Development Program(2022YFC2504500);a collaborative scientific project co-established by the Science and Technology Department of the National Administration of Traditional Chinese Medicine and the Zhejiang Provincial Administration of Traditional Chinese Medicine(GZY-ZJKJ-24082);the General Health Science and Technology Program of Zhejiang Province(2024KY1099);Project of Zhejiang University Longquan Innovation Center(ZJDXLQCXZCJBGS2024016);Hongying Ni received funding from Jinhua Science and Technology Planning Project(2024-3-047).
Objective:To develop and demonstrate a comprehensive methodological framework for target trial emulation(TTE)implementation via post-laparoscopic septic shock fluid management as a clinical case study.Methods:We desig...
关键词:Laparoscopic surgery SEPSIS Target trial emulation 
Mortality Reduction and Food Consumption of Fall Armyworms Spodoptera frugiperda and Non-Target Insect Cirina butyrospermi after Exposure to Burkinabe Native Entomopathogenic fungi Metarhizium sp.
《Advances in Entomology》2025年第1期68-74,共7页Etienne Bilgo Hien D. François Issiaka Saré Abdoulaye Diabaté 
Fall Armyworms (FAW) Spodoptera frugiperda, particularly in maize crops, is a major agricultural pest. Current control methods rely heavily on chemical pesticides, which are costly and harmful to non-target organisms....
关键词:Fall Armyworms Burkina Faso METARHIZIUM BIOCONTROL Entomopathogenic fungi 
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