Iron-handling solute carrier SLC22A17 as a blood-brain barrier target after stroke  

作  者:Xueqi Ren Wenlu Li 

机构地区:[1]Key Laboratory of Neuropharmacology and Translational Medicine of Zhejiang Province,School of Pharmaceutical Sciences,Zhejiang Chinese Medical University,Hangzhou,Zhejiang Province,China [2]Neuroprotection Research Laboratories,Departments of Radiology and Neurology,Massachusetts General Hospital,Harvard Medical School,Boston,MA,USA

出  处:《Neural Regeneration Research》2025年第11期3207-3208,共2页中国神经再生研究(英文版)

摘  要:The pathophysiology of ischemic stroke is complex and multifactorial,involving various forms of cell death such as apoptosis,autophagy,and necrosis.A recent study suggests that oxidative and inflammatory stress can induce ferroptosis,a specialized form of cell death characterized by the accumulation of lipid peroxides dependent on intracellular iron overload(Li and Jia,2023).

关 键 词:DEATH specialized BARRIER 

分 类 号:R743.3[医药卫生—神经病学与精神病学]

 

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