supported by the National Key Research and Development Program of China(No.2022YFA1103400);the CAMS Innovation Fund for Medical Sciences(No.2019-I2M-5e056);the National Natural Science Foundation of China(No.81930119,92168207,32371477,82090051);the Precision Medicine Research Program of Tsinghua University(No.10001020612);the National High Level Hospital Clinical Research Funding(China)(No.2022-NHLHCRF-LX-03-0102).
Hepatocyte proliferation is essential for recovering liver function after injury. Inliver surgery, the mechanical stimulation induced by hemodynamic changes triggers vascularendothelial cells (VECs) to secrete large a...
supported by grants from National Natural Science Foundation of China(81973356 to CLS);National Key R&D Program of China(2017YFC1104400 to JPL).
Histone lysine-specific demethylase 1(LSD1)is overexpressed in various solid and hematological tumors,suggesting its potential as a therapeutic target,but there are currently no LSD1 inhibitors available on the market...