supported by the Michael J Fox Foundation (to PA and FZ)。
The lysosomal enzyme β-glucocerebrosidase(GCase) belongs to the family of glycosidases and hydrolyses the glycosphingolipid glucosylceramide(GluCer) into glucose and ceramide. The enzyme is of central importance for ...
supported by the National Natural Science Foundation of China,Nos.32371070 (to JT),31761163005 (to JT),32100824 (to QX);the Shenzhen Science and Technology Program,Nos.RCBS20210609104606024 (to QX),JCY20210324101813035 (to DL);the Guangdong Provincial Key S&T Program,No.2018B030336001 (to JT);the Key Basic Research Program of Shenzhen Science and Technology Innovation Commission,Nos.JCYJ20200109115405930 (to JT),JCYJ20220818101615033 (to DL),JCYJ20210324115811031 (to QX),JCYJ20200109150717745 (to QX);Shenzhen Key Laboratory of Neuroimmunomodulation for Neurological Diseases,No.ZDSYS20220304163558001 (to JT);Guangdong Provincial Key Laboratory of Brain Connectome and Behavior,No.2023B1212060055 (to JT);the China Postdoctoral Science Foundation,No.2021M693298 (to QX)。
The conventional perception of astrocytes as mere supportive cells within the brain has recently been called into question by empirical evidence, which has revealed their active involvement in regulating brain functio...
supported by grants from the National Natural Science Foundation of China(32371222 to Z.X.,32330047 and 31930057 to F.W.,31970689 to J.M.,and 32200961 to Xiaopeng Li);the Zhejiang University School of Public Health Interdisciplinary Research Innovation Team Development Project.
The identification of aging-and longevity-associated genes is important for promoting healthy aging.By analyzing a large cohort of Chinese centenarians,we previously found that single-nucleotide polymorphisms(SNPs)in ...
supported by grants from the Biological Breeding-National Science and Technology Major Project(2023ZD04072);the National Natural Science Foundation of China(32302660,32025004,and 31921001).
Maize(Zea mays)is the most widely cultivated crop in the world.Maize production is closely linked to the extensive uptake and utilization of various mineral nutrients.Potassium(K),calcium(Ca),and magnesium(Mg)are esse...
funded by the Natural Science Foundation of Guangdong Province,China(Grant Nos.2023A1515012617,2022A1515010458 and 2023A1515030267);Guangzhou Science&Technology Program(Grant No.202201010410);the earmarked fund for CARS-32。
Major facilitator superfamily(MFS)transporters are secondary active membrane transporters that play an important role in solute interchange and energy metabolism.Peronophythora litchii causes the most destructive dise...
supported by the National Natural Science Foundation of China(NSFC)(No.82360065 and No.81760047).
Objective Atrial natriuretic peptide(ANP)and Zn^(2+)have been shown to confer cardioprotection against ischemia/reperfu-sion(I/R)injury.Zn^(2+)alleviates myocardial hypertrophy and pulmonary hypertension by regulating...
supported by the Universiti Kebangsaan Malaysia under the Research University Grant(No.GUP-2020-030)awarded to Sylvia CHIENG.
Adenosine triphosphate(ATP)-binding cassette(ABC)transporter systems are divided into importers and exporters that facilitate the movement of diverse substrate molecules across the lipid bilayer,against the concentrat...
supported by the National Natural Science Foundation of China (31671594);Guangdong Basic and Applied Basic Research Foundation (2024A1515011098,2021A1515012482).
The involvement of the endoplasmic reticulum(ER)-localized adenylate transporter1(ER-ANT1)in photorespiratory metabolism has been established,yet its precise physiological function remains uncertain.Rice er-ant1 mutan...
supported by the National Natural Science Foundation of China (32060064/32260498);the Guizhou Provincial Excellent Young Talents Project of Science and Technology (Qiankehepingtairencai-YQK (2023)002);the Guizhou Provincial Science and Technology Projects (Qiankehejichu-ZK (2021)General 128;Qiankehejichu-ZK (2022)Key 008;Qiankehechengguo (2024)General 116;Qiankehepingtairencai-BQW (2024)001,qiankehepingtai-YWZ (2024)004);the Key Laboratory of Molecular Breeding for Grain and Oil Crops in Guizhou Province (Qiankehezhongyindi (2023)008);the Key Laboratory of Functional Agriculture of Guizhou Provincial Department of Education (Qianjiaoji (2023)007);the Qiandongnan Science and Technology Support Project (Qiandongnan Kehe Support (2023)06).
Amino acids are the primary form of nitrogen utilization in higher plants,mainly transported by amino acid transporters.In this study,we analyzed the natural variation of amino acid transporter-like 4(OsATL4)in rice g...
financially supported by the Hunan Engineering Research Center of Intelligent Animal Husbandry(grant number:20211231GCZX)of China;Evaluation of the Effectiveness of Iron Dextran Supplementation in Pig Diets(grant number,2022xczx-214)of Hunan Agricultural University.
The purpose of this study was to gain insight into the mechanism of iron dextran(DexFe)absorption in the intestines.A total of 72 piglets(average BW=7.12±0.75 kg,male to female ratio=1:1)weaned at 28 d of age were ra...