supported by the Michael J Fox Foundation (to PA and FZ)。
The lysosomal enzyme β-glucocerebrosidase(GCase) belongs to the family of glycosidases and hydrolyses the glycosphingolipid glucosylceramide(GluCer) into glucose and ceramide. The enzyme is of central importance for ...
partially supported by grants PID2020-115096RB-I00 and PID2023-148273NB-I00 from Ministerio de Ciencia y Universidad (MICIU/AEI)(to EMS)。
GEMIN5 is a predominantly cytoplasmic multifunctional protein, known to be involved in recognizing snRNAs through its WD40 repeats domain placed at the N-terminus. A dimerization domain in the middle region acts as a ...
supported by the National Natural Science Foundation of China(No.81802406);Shandong Provincial Natural Science Foundation of China(No.ZR2021MH045,ZR2020LZL009,ZR2019BH061,ZR2021MH225);Special Funds for Scientific Research on Breast Diseases of Shandong Medical Association of China(No.YXH2021ZX058).
circular RNA (circRNA) is a covalently closed single-stranded RNA that lacks 5’ and 3’ends and has long been considered a noncoding RNA. With the development of high-throughputsequencing and bioinformatics technolog...
funded by the Israel Science Foundation(grants No.1036/12 and 1228/20)(to OES).
Translation regulation is an important layer of gene expression:Generation of genome-wide expression datasets at multi-omics levels in spatial,temporal,and cell-type resolution is essential for deciphering brain compl...
Prof.Jiang Lin's recent book,Breaking Free:Liang Qchao's"Ungttred Translation"and Its Legagy,paved the way for translation history studies in a people-centered framework.This would allow scholars to gain not only know...
financed by the grants from the Research Program of Sichuan TCM Culture Coordinated Development Research Center (No. 2021XT31);National Traditional Chinese Medicine Examination Research Project (No. TC2023019);National Innovation & Entrepreneurship Training Program for College Students (No. 202210633008X)。
Traditional Chinese medicine(TCM) is increasingly recognized worldwide as a valuable complementary and alternative medicine. To facilitate global research and collaboration in this field, the World Health Organization...
supported by the National Natural Science Foundation of China(82121001,82222008,82070338,82470330);the Fundamental Research Funds for the Central Universities.
Atrial fibrillation(AF)is the most common arrhythmia,which is tightly associated with the abnormal expression and function of ion channels in the atrial cardiomyocytes.N^(6)-methyladenosine(m^(6)A),a widespread chemic...
Seven years after Lin Yi-han's death,her only novel,based on her real-life experiences,is now available in English.It tells a harrowing story of rape,trauma,and enduring power structures that continue to allow such st...
Humanities and Social Sciences Research Project of China’s Ministry of Education(23YJCZH242);Major Humanities and Social Sciences Research Projects in Zhejiang Higher Education Institutions(2024QN069);Hangzhou Collaborative Innovation Institute of Language Services,Hangzhou City University,China。
This article centers on The Call of the Wild,an English novel by American author Jack London,alongside two Chinese translations by Dajie Liu and Menglin Zhang,and Rongyue Liu.Seventy sentences containing motion events...
supported by the Postdoctoral Fellowship Program of CPSF(No.GZC20230333,China).
Nanomedicines have revolutionized disease prevention,diagnosis,and treatment.Since the approval of Liposomal doxorubicin(Doxil)in 1995,various nanomedicines have been successfully developed1.Specifically,the COVID-19 ...