云南高校图书馆联盟文献共享服务平台- SLC

SLC: 作品数：283被引量：272H指数：8; 导出分析报告; 相关领域：医药卫生自动化与计算机技术更多>>; 相关作者：张叔人张昌菊梁春敏肖明威董忠军更多>>; 相关机构：华中科技大学中国科学院三峡大学美光科技公司更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家高技术研究发展计划国家重点基础研究发展计划山东省自然科学基金更多>>

Newly identified intronic and known pathogenic point mutations in SLC34A3/NPT2c cause hereditary hypophosphatemic rickets with hypercalciuria: 《Genes & Diseases》2025年第2期68-71,共4页Yujing Sun Yuan Liu Xiaoli Zhang Ling Jiang; funded by the National Natural Science Foundation of China Youth Fund (No.82200918);the Natural Science Foundation of Shandong Province Youth Fund (China) (No.ZR2021QC111).; Hereditary hypophosphatemic rickets with hypercalciuria(HHRH)is a rare autosomal recessive disorder characterized by hypophosphatemia,hypercalciuria,and recurrent nephrolithiasis,often resulting in rickets and osteoma...; 关键词：calci SLC HEREDITARY

A Novel Role for the Longevity-Associated Protein SLC39A11 as a Manganese Transporter: 《Research》2025年第1期1-14,共14页Zhidan Xia Biyao Tang Xiaopeng Li Xinran Li Yangfan Jia Jianwei Jiang Jingyao Chen Jingshu Song Siyi Liu Junxia Min Fudi Wang; supported by grants from the National Natural Science Foundation of China(32371222 to Z.X.,32330047 and 31930057 to F.W.,31970689 to J.M.,and 32200961 to Xiaopeng Li);the Zhejiang University School of Public Health Interdisciplinary Research Innovation Team Development Project.; The identification of aging-and longevity-associated genes is important for promoting healthy aging.By analyzing a large cohort of Chinese centenarians,we previously found that single-nucleotide polymorphisms(SNPs)in ...; 关键词：Hutchinson Gilford progeria syndrome ZEBRAFISH reactive oxygen species manganese transporter SLC cellular senescence

肠道金属离子转运体SLC30A1是调控机体循环锌离子稳态的关键: 《浙江大学学报(医学版)》2025年第1期48-48,共1页; 2024年10月18日,浙江大学医学院闵军霞、王福俤教授团队联合张岩教授团队在《先进科学》(Advanced Science)发表题为“The intestinal transporter SLC30A1 plays a critical role in regulating systemic zinc homeostasis”的研究论文...; 关键词：浙江大学医学院离子稳态肠道上皮细胞肠道屏障冷冻电镜 SLC 锌离子

牦牛附睾不同区段上皮细胞SLC基因家族的表达分析: 《南方农业学报》2024年第11期3404-3413,共10页吴逸韬潘美兰罗小凤潘城赵旺生; 中央引导地方科技发展资金项目(2023ZY026);四川省科技计划项目(2021YFH0101);西南科技大学研究生精品课程和双语课程建设项目(20SYKC05)。; 【目的】揭示附睾不同区段溶质载体(SLC)蛋白的调控及功能差异,明确SLC基因家族在牦牛附睾中的表达情况,为提高牦牛繁育性能提供理论依据。【方法】从牦牛附睾头、附睾体和附睾尾的上皮细胞转录组数据中筛选出54个SLC基因家族差异表达基...; 关键词：牦牛附睾上皮细胞 SLC基因家族差异表达基因(DEGs)

SLC家族在三阴性乳腺癌代谢中的研究进展: 《中国医药科学》2024年第22期13-16,共4页李雪孙立; 国家自然科学基金(82272668)。; 近年来,靶向溶质载体(SLC)家族已成为癌症药理学和药物发现领域的研究热点。SLC家族转运蛋白参与多种溶质(无机离子、氨基酸、神经递质和药物等)的跨膜运输及维持细胞的代谢。自20世纪20年代Warburg效应被发现以来,癌细胞内的代谢重编...; 关键词：三阴性乳腺癌溶质载体家族代谢肿瘤

The role of SLC26A8 homozygous variants in male infertility and flagellum abnormalities: 《Asian Journal of Andrology》2024年第5期544-546,共3页Bin Mao Sha-Sha Zhang Liang-Tao Zhao Hui-Rong Huang Feng-Die Ma Wen-Jing Shi Shan Li Zi-Yan Nie Han-Dan Xiao Xiao-Dong Xie Pei-Qiang Li; support from grants provided by the Gansu Provincial Natural Science Foundation of China(23JRRA1046);the Gansu Association for Science and Technology(GSHZTS 2022-04);the National College Student Innovation and Entrepreneurship Training Program(202310730222).; Dear Editor,Solute carrier family 26 member 8(SLC26A8)gene belongs to the solute carrier 26(SLC26)family.It demonstrates distinct expression in male spermatozoa.This gene potentially plays a role in the formation of t...; 关键词：INFERTILITY SLC linking

包裹SLC对神经酰胺合成途径中关键酶的调控作用: 《当代化工研究》2024年第14期5-8,共4页林琳徐思伟王蕊蕊; 包裹水杨酰植物鞘氨醇(SLC)解决了SLC溶解性差的问题,样品稳定、耐寒耐热,并且增强了SLC在表皮的透皮吸收率。在包裹SLC对神经酰胺合成途径中关键酶基因表达测试中,结果显示包裹SLC对SPTLC2、CerS3、DEGS1和KDSR基因表达具有明显调控作...; 关键词：水杨酰植物鞘氨醇透皮吸收合成途径基因表达

SLC25A21在肾透明细胞癌发病机制中的作用: 《中国老年学杂志》2024年第12期2970-2974,共5页顾有为李雅舒沈璐妍王潇然欧文王勇; 吉林省科学技术厅自然科学基金项目(212558JC010486547); 目的探讨SLC25A21在肾透明细胞癌细胞(786-0)中的作用。方法利用实时荧光定量-聚合酶链反应(RT-qPCR)、免疫荧光及Western印迹分析786-0中SLC25A21表达差异。慢病毒感染786-0构建SLC25A21过表达人肾透明细胞癌细胞系SLC25A21-OE,通过Tra...; 关键词：线粒体溶质载体家族(SLC)25A21 肾透明细胞癌细胞786-0

Substrate and drug recognition mechanisms of SLC19A3: 《Cell Research》2024年第6期458-461,共4页Yu Dang Tianyi Zhang Shabareesh Pidathala Guopeng Wang Yijie Wang Nanhao Chen Chen Song Chia-Hsueh Lee Zhe Zhang; funded by the National Key R&D Program of China(2021YFA1302300 to Z.Z.);the National Natural Science Foundation of China(32171201 to Z.Z.);The study was also supported by the Center for Life Sciences School of Life Sciences of Peking University,the State Key Laboratory of Membrane Biology of China(to Z.Z.),and ALSAC(to C.-H.L.).; Dear Editor,Vitamins B,and Bo are two water-soluble vitamins.Their active forms thiamine pyrophosphate and pyridoxal 5'-phosphate serve as cofactors for numerous enzymes involved in multiple biochemical reactions that...; 关键词：VITAMIN METABOLISM SLC

Impact of genetic variants in the solute carrier(SLC)genes encoding drug uptake transporters on the response to anticancer chemotherapy: 《Cancer Drug Resistance》2024年第1期553-576,共24页Jose J.G.Marin Maria A.Serrano Elisa Herraez Elisa Lozano Sara Ortiz-Rivero Laura Perez-Silva Maria Reviejo Oscar Briz; funding from CIBEREHD,Fondo de Investigaciones Sanitarias,Instituto de Salud Carlos Ⅲ co-funded by European Regional Development Fund/European Social Fund,“Investing in your future”)(PI19/00819,PI20/00189,PI23/00681,and PI22/00526);Junta de Castilla y León(SA074P20,GRS 2322/A/21,and SA113P23);FundacióMarato TV3(Ref.201916-31),Fundación AECC(AECC2023/2027);University of Salamanca(PC_TCUE21-23_011);Spain.Reviejo M was supported by a postdoctoral contract funded by the“Junta de Castilla y Leon”(SA113P23).; Cancer drug resistance constitutes a severe limitation for the satisfactory outcome of these patients.This is a complex problem due to the co-existence in cancer cells of multiple and synergistic mechanisms of chemore...; 关键词：Cancer CHEMOTHERAPY PHARMACOGENETICS single nucleotide alteration single nucleotide polymorphism transportome

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