DEMENTIA

作品数:549被引量:1256H指数:16
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相关领域:医药卫生更多>>
相关作者:刘博符健周鼒方亚傅新星更多>>
相关机构:首都医科大学厦门大学南京医科大学附属脑科医院上海市医学科学技术情报研究所更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金上海市自然科学基金更多>>
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Potential biofluid markers for cognitive impairment in Parkinson's disease
《Neural Regeneration Research》2026年第1期281-295,共15页Jieyu Chen Chunyu Liang Fang Wang Yongyun Zhu Liuhui Zhu Jianzhun Chen Bin Liu Xinglong Yang 
supported by Applied Basic Research Foundation of Yunnan Province,Nos.202301AS070045,202101AY070001-115(to XY and BL);National Natural Science Foundation of China,No.81960242(to XY)。
Cognitive impairment is a particularly severe non-motor symptom of Parkinson's disease that significantly diminishes the quality of life of affected individuals.Identifying reliable biomarkers for cognitive impairment...
关键词:amyloid-β biomarkers cognitive impairment DEMENTIA metabolomics NEURODEGENERATION NEUROINFLAMMATION Parkinson's disease proteomics tau Α-SYNUCLEIN 
Decoding molecular mechanisms:brain aging and Alzheimer's disease
《Neural Regeneration Research》2025年第8期2279-2299,共21页Mahnoor Hayat Rafay Ali Syed Hammad Qaiser Mohammad Uzair Khalid Al-Regaiey Roaa Khallaf Lubna Abdullah Mohammed Albassam Imdad Kaleem Xueyi Wang Ran Wang Mehwish SBhatti Shahid Bashir 
The complex morphological,anatomical,physiological,and chemical mechanisms within the aging brain have been the hot topic of research for centuries.The aging process alters the brain structure that affects functions a...
关键词:Alzheimer’s disease brain aging cognitive health DEMENTIA molecular mechanisms neuronal activity NEUROPLASTICITY NEUROTRANSMISSION 
The correlation between loneliness and dementia fear among elderly people in the community
《Nursing Communications》2025年第6期1-7,共7页Jia-Wei Du Han-Yun Guan Li-Hua Jin 
Background:To understand the current situation of loneliness and dementia fear among elderly people in the community;Analyze the influencing factors and clarify the correlation between the two.Methods:Through convenie...
关键词:community elderly LONELINESS dementia fear 
Dynamic Spatial Focus in Alzheimer’s Disease Diagnosis via Multiple CNN Architectures and Dynamic GradNet
《Computers, Materials & Continua》2025年第5期2109-2142,共34页Jasem Almotiri 
funded by Taif University,Saudi Arabia;The author would like to acknowledge Deanship of Graduate Studies and Scientific Research,Taif University for funding this work.
The evolving field of Alzheimer’s disease(AD)diagnosis has greatly benefited from deep learning models for analyzing brain magnetic resonance(MR)images.This study introduces Dynamic GradNet,a novel deep learning mode...
关键词:Spatial focus GradCAM medical image classification deep learning early dementia detection neurodegenerative disease MRI analysis Alzheimer’s attention CNN 
Memory’s Last Stand The race against Alzheimer's disease
《Beijing Review》2025年第14期40-41,共2页Yuan Yuan 
After brewing a cup of coffee,85-year-old Dai Xiuyu suddenly forgets the steps she just learned and turns to a social worker for guidance-this scene replayed daily at Unforgettable Cafe in Chengdu,capital of southwest...
关键词:elderly individuals cognitive impairmentsincluding MEMORY cognitive impairments social worker Alzheimers disease DEMENTIA China social workers 
Motoric cognitive risk syndrome:A review of fall risk assessment and management strategies
《World Journal of Psychiatry》2025年第4期14-25,共12页Hao Peng Na Yao Yan-Ping Song Li Huang Hong-Bo Chen Yang Jiang Qi-Gang Chen 
The aging global population is driving an increase in dementia,making the early identification of at-risk individuals crucial.Studies have shown that elderly people often exhibit a slowing gait before dementia diagnos...
关键词:Motoric cognitive risk syndrome DEMENTIA Gait slowing Fall risk Early intervention 
A study of connectivity features analysis in brain function network for dementia recognition
《Nanotechnology and Precision Engineering》2025年第1期79-93,共15页Siying Li Peng Wang Zhenfeng Li Lidong Du Xianxiang Chen Jie Sun Libin Jiang Gang Cheng Zhen Fang 
supported by the National Natural Science Foundation of China(Grant Nos.62071451,62331025,and U21A20447);the National Key Research and Development Project(Grant No.2021YFC3002204);the CAMS Innovation Fund for Medical Sciences(Grant No.2019-I2M-5-019).
Dementias such as Alzheimer disease(AD)and mild cognitive impairment(MCI)lead to problems with memory,language,and daily activities resulting from damage to neurons in the brain.Given the irreversibility of this neuro...
关键词:ELECTROENCEPHALOGRAPHY Brain function network Machine learning Feature selection Dementia recognition 
Deep Learning and Machine Learning Architectures for Dementia Detection from Speech in Women
《Computer Modeling in Engineering & Sciences》2025年第3期2959-3001,共43页Ahlem Walha Amel Ksibi Mohammed Zakariah Manel Ayadi Tagrid Alshalali Oumaima Saidani Leila Jamel Nouf Abdullah Almujally 
funded by the Deanship of Scientific Research at Princess Nourah bint Abdulrahman University,through the Research Groups Program Grant No.(RGP-1444-0057).
Dementia is a neurological disorder that affects the brain and its functioning,and women experience its effects more than men do.Preventive care often requires non-invasive and rapid tests,yet conventional diagnostic ...
关键词:Dementia detection in women Alzheimer’s disease deep learning machine learning support vector machine voting classifier 
Ability of clock drawing errors on Mini-Cog test to predict development of delirium after major urological cancer surgery
《Current Urology》2025年第1期64-69,共6页Shugo Yajima Yasukazu Nakanishi Shunya Matsumoto Naoya Okubo Kenji Tanabe Madoka Kataoka Hitoshi Masuda 
Background:This study aimed to evaluate the impact of the clock drawing test(CDT)on postoperative delirium and compare the abilities of the mini-cognitive(Mini-Cog)test and the CDT for predicting postoperative deliriu...
关键词:Cognitive dysfunction DELIRIUM DEMENTIA Robotic surgery UROLOGY 
Advances in synaptic PET imaging and intervention with synapse-targeted small-molecular drugs for dementia diagnosis and therapy被引量:1
《Fundamental Research》2025年第1期63-71,共9页Xiuhong Lu Bin Ji Gang Huang Hong Ding 
funding support from the National Natural Science Foundation of China(81971016);Shanghai Science and Technology program(21010502300);Construction project of Shanghai Key Laboratory of Molecular Imaging(18DZ2260400).
Dementia is characterized by synaptic and neuronal dysfunction in disease-specific brain regions.Repeated failure of dementia clinical trials with therapeutic drugs targeting abnormal protein aggregates has caused res...
关键词:Synaptic density imaging Synaptic vesicle protein 2A DEMENTIA Multimodal imaging UCB-J Positron emission tomography 
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