ANTIDEPRESSANT

作品数：124被引量：390H指数：10
导出分析报告
相关领域：医药卫生更多>>
相关作者：侯正华袁勇贵尹营营祁金顺钟启星更多>>
相关机构：东南大学中国药科大学山西医科大学上海中医药大学更多>>
相关期刊：更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划北京市自然科学基金中国博士后科学基金更多>>
-
在结果中检索

检索结果分析

结果分析中...
共 条 记 录，以下是1-10
全选清除导出
参考文献引证文献引用追踪
视图：
排序：
Selective serotonin reuptake inhibitors in the treatment of major depressive disorder after brain trauma:Systematic review and metaanalysis
《World Journal of Psychiatry》2025年第3期311-318,共8页Ren-Xian Gao Xiao-Na Zhang Peng Zhu 
BACKGROUND Traumatic brain injury(TBI)poses a considerable risk to human health.After TBI,individuals are susceptible to a range of psychiatric disorders,with depression being a primary complication.Selective serotoni...
关键词：ANTIDEPRESSANT META-ANALYSIS DEPRESSION Traumatic brain injury Selective serotonin reuptake inhibitors 
Quantitative proteomic analysis of the brain reveals the potential antidepressant mechanism of Jiawei Danzhi Xiaoyao San(加味丹栀逍遥散) in a chronic unpredictable mild stress mouse model of depression
《Journal of Traditional Chinese Medicine》2025年第1期22-31,共10页LI Yajing WANG Baoying SHAO Wenxue LU Shuaifei SU Pan BAI Ming XU Erping LI Yucheng 
the National Natural Science Foundation of China:Study on the Biological Basis of Jiawei Danzhi Xiaoyaosan in Treatment of Depression based on Network Pharmacology and Proteomics(No.81973739);Natural Science Excellent Youth Fund of Henan Province:the Mechanism of Baicalin Regulates the GSK3B-Mediated Axoplasmic Transport in the Treatment of Depression(No.202300410249);Science and Technology Research Project of Henan Province:Study on the Antidepressant Mechanism of Jiawei Danzhi Xiaoyaosan based on the NOD-like Receptor Thermal Protein Domainassociated Protein and Tripartite Motif-containing Protein 31 Ubiquitination Pathway(No.222102310233);Study on the Mechanism of Jiawei Danzhi Xiaoyaosan in the Treatment of Depression by Regulating M1/M2 Polarization and Microglia Autophagy(No.232102310419)。
OBJECTIVE:To reveal the antidepressant mechanisms of Jiawei DanZhiXiaoYaoSan(加味丹栀逍遥散,JD)in chronic unpredictable mild stress(CUMS)-induced depression in mice.METHODS:Using the CUMS mouse model of depression,the...
关键词：DEPRESSION PROTEOMICS intermediate filaments mitogen-activated protein kinases Jiawei Danzhi Xiaoyaosan 
Negative efficacy of antidepressants in pharmacotherapy of child and adolescent depression
《World Journal of Psychiatry》2025年第1期32-36,共5页Min Xu Hai-Ying Jin Feng-Li Sun Wei-Dong Jin 
Antidepressants are the main drugs used to treat depression,but they have not been shown to be effective in the treatment of child and adolescent depression.However,many adolescent depression treatment guidelines stil...
关键词：Child depression Adolescent depression ANTIDEPRESSANT Switch SUICIDE Non-suicidal self injury 
The efficacy and safety of NeuroWell antidepressant dietary supplement,Deanxit,and their combination in the treatment of mild-to-moderate depression:A randomized clinical trial
《Genes & Diseases》2024年第6期36-39,共4页Honglei Yin Zhuxin Sui Yutong Wang Dechen Liu Qinglu Wang Yanchao Wang Lei Sun Jinfeng Li Zhen Li Yue Liu Shang Guo Wenwen Wang Hongtao Yin Ping Liu Kezhong Zhang Huaibo Zhang Yajun Liu Yanqiu Liu Qiqi Zhou Dianfang Wei Hui Zhang Shanshan Wang Yaochao Ning Shuang Geng Xuejun Wen Youping Deng Hongwei Wang Yunliang Wang 
supported by the Second Affiliated Hospital of Zhengzhou University and Zibo 148 Hospital,Qilu Medical University (Shandong,China),XREGEN Research Institute,Shangqiu Medical College (Henan,China).
Depression is the leading global cause of,disability,affecting about 300 milion people worldwide.1;2 Depending on the number and severity of symptoms,depressive episodes can be classified as mild,moderate,and severe.P...
关键词：TREATMENT clinical typically 
Interaction between Gut Microbiota and Medicinal Food Homology in Depression
《Journal of Biosciences and Medicines》2024年第11期190-205,共16页Tian Yu 
Depression can be counted as the most severe mental disease in the world nowadays, which lacks effective curing treatments. With an increasing number of patients, developing effective treatments with fewer side effect...
关键词：Medicinal Food Homology Gut Microbiota DEPRESSION ANTIDEPRESSANT PATHOGENESIS 
Association between 5-HTR1A gene C-1019G polymorphism and antidepressant response in patients with major depressive disorder:A meta-analysis
《World Journal of Psychiatry》2024年第10期1573-1582,共10页Huai-Neng Wu Shuang-Yue Zhu Li-Na Zhang Bian-Hong Shen Lian-Lian Xu 
BACKGROUND Major depressive disorder(MDD)is a substantial global health concern,and its treatment is complicated by the variability in individual response to antide-pressants.AIM To consolidate research and clarify th...
关键词：Major depressive disorder Antidepressant efficacy 5-HTR1A gene C-1019G polymorphism META-ANALYSIS 
A novel positive modulator of GABA_(A) receptor exhibiting antidepressive properties
《生理学报》2024年第5期677-690,共14页ZHENG Yin-Li SHEN Fu-Yi WANG Yang PAN Jing-Pei WANG Xian LI Tian-Yu DU Wei-Jia LIU Zhi-Qiang LI Yang GUO Fei 
γ-Aminobutyric acid(GABA) neurotransmission alterations have been implicated to play a role in depression pathogenesis. While GABA_(A) receptor positive allosteric modulators are emerging as promising in clinical pra...
关键词：ANTIDEPRESSANT GABAa receptor positive modulator NEUROTRANSMISSION 
Single-cell RNA sequencing facilitates the elucidation of the complete biosynthesis of the antidepressant hyperforin in St. John's wort
《Molecular Plant》2024年第9期1439-1457,共19页Song Wu Ana Luisa Malaco Morotti Jun Yang Ertao Wang Evangelos C.Tatsis 
supported by the National Natural Science Foundation of China,Research Fund for International Excellent Young Scientists(RFIS-Il)(grant 32150610477,awarded to E.C.T.);Strategic Priority Research Program of the Chinese Academy of Sciences(grant XDB27020204,awarded to E.C.T.);Chinese Academy of Sciences,International Partnership Program of CAS(grant 153D31 KYSB20160074,awarded to E.C.T.);National Key Laboratory of Plant Molecular Genetics Special Fund.
Hyperforin is the compound responsible for the effectiveness of St.John's wort(Hypericum perforatum)as an antidepressant,but its complete biosynthetic pathway remains unknown.Gene discovery based on co-expression anal...
关键词：HYPERFORIN Hypericum perforatum de novo genome sequencing single-cell RNA sequencing biosyn-thetic pathway MEROTERPENOIDS 
Rapid Antidepressant-Like Potential of Chaihu Shugan San Depends on Suppressing Glutamate Neurotransmission and Activating Synaptic Proteins in Hippocampus of Female Mice被引量：1
《Chinese Journal of Integrative Medicine》2024年第8期692-700,共9页LU Chao GAO Zi-wei XING Shan WANG Hui-hui HUANG Yun-ke ZHOU Hang WU Lei 
Supported by the National Natural Science Foundation of China(No.82174107,82304898);Jiangsu Provincial Administration of Traditional Chinese Medicine Fund(No.YB2020014);the Priority Academic Program Development of Jiangsu Higher Education Institutions(No.035062005001)。
Objective To explore the rapid antidepressant potential and the underlying mechanism of Chaihu Shugan San(CSS)in female mice.Methods Liquid chromatography mass spectrometry(LC-MS)/MS was used to determine the content ...
关键词：Chaihu Shugan San female rapid antidepressant potential N-methyl-D-aspartate receptor synapticprotein optogenetic Chinesemedicine 
From Perspective of Hippocampal Plasticity:Function of Antidepressant Chinese Medicine Xiaoyaosan
《Chinese Journal of Integrative Medicine》2024年第8期747-758,共12页ZHANG Wu-jing GUO Ze-xuan WANG Yi-di FANG Shao-yi WAN Chun-miao YU Xiao-long GUO Xiao-fang CHEN Yue-yue ZHOU Xuan HUANG Jun-qing LI Xiao-juan CHEN Jia-xu FAN Li-li 
Supported by the National Natural Science Foundation of China(No.82304746);Jinan University Innovation and Entrepreneurship Training Program for Undergraduate(No.CX21255 and CX22481)。
The hippocampus is one of the most commonly studied brain regions in the context of depression.The volume of the hippocampus is significantly reduced in patients with depression,which severely disrupts hippocampal neu...
关键词：DEPRESSION hippocampal neuroplasticity Xiaoyaosan Chinese medicine 
全选清除导出
共13页<12345678910>
检索报告 对象比较 聚类工具 使用帮助 返回顶部