MEROTERPENOIDS

作品数：29被引量：33H指数：3
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相关领域：医药卫生更多>>
相关机构：北京大学兰州大学更多>>
相关期刊：《Journal of Future Foods》《Molecular Plant》《Chinese Journal of Chemistry》《Natural Products and Bioprospecting》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划广东省自然科学基金中国博士后科学基金更多>>
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Unveiling the Mechanisms of Apoptosis Induction by Deep-Sea-Derived Polyketide-Terpenoid Hybrids from Penicillium allii-sativi:A Focus on Mitochondrial and mTOR Pathways
《Chinese Journal of Chemistry》2024年第24期3283-3292,共10页Chun-Lan Xie Tai-Zong Wu Duo Zhang Yuan Wang Ting Lin Hai-Feng Chen Xiao-Kun Zhang Xian-Wen Yang 
supported by the National Key Research and Development Program of China(2022YFC2084103);Xiamen Southern Oceanographic Center(22GYY007HJ07);the National Natural Science Foundation of China(22177143).
A chemical investigation of the deep-sea-derived fungus Penicillium allii-sativi MCCC 3A00580 resulted in the discovery of four new meroterpenoids(1—4)and one related known co-metabolite(5).These meroterpenoids showc...
关键词：Deep-sea-derived fungus Penicillium allii-sativi MEROTERPENOIDS Drimane sesquiterpene Peroxide Mitochondrial apoptosis mTOR Cancer treatment TERPENOID Structure elucidation 
Single-cell RNA sequencing facilitates the elucidation of the complete biosynthesis of the antidepressant hyperforin in St. John's wort
《Molecular Plant》2024年第9期1439-1457,共19页Song Wu Ana Luisa Malaco Morotti Jun Yang Ertao Wang Evangelos C.Tatsis 
supported by the National Natural Science Foundation of China,Research Fund for International Excellent Young Scientists(RFIS-Il)(grant 32150610477,awarded to E.C.T.);Strategic Priority Research Program of the Chinese Academy of Sciences(grant XDB27020204,awarded to E.C.T.);Chinese Academy of Sciences,International Partnership Program of CAS(grant 153D31 KYSB20160074,awarded to E.C.T.);National Key Laboratory of Plant Molecular Genetics Special Fund.
Hyperforin is the compound responsible for the effectiveness of St.John's wort(Hypericum perforatum)as an antidepressant,but its complete biosynthetic pathway remains unknown.Gene discovery based on co-expression anal...
关键词：HYPERFORIN Hypericum perforatum de novo genome sequencing single-cell RNA sequencing biosyn-thetic pathway MEROTERPENOIDS 
Hyperlanins A and B, Two Highly Rearranged Meroterpenoids from Hypericum lancasteri
《Chinese Journal of Chemistry》2024年第18期2180-2186,共7页Jin-Qiu You Yun-Qi Jin Meng-Yu Li Bo-Chao Zhang Xin-Yu Sun Chun-Yong Ding Jing-Ya Li Ai-Jun Hou 
supports from the National Natural Science Foundation of China(Grant No.22277074);Zhiyuan Future Scholar Program(Grant No.ZIRC2022-14)of Zhiyuan College,Shanghai Jiao Tong University are gratefully acknowledged.
Hyperlanins A(1)and B(2),two highly rearranged polycyclic polyprenylated acylphloroglucinol(PPAP)-related meroterpenoids based on different new carbon skeletons,were isolated from Hypericum lancasteri.Compound 1 incor...
关键词：Natural products Hypericum lancasteri MEROTERPENOIDS STRUCTUREELUCIDATION INFLAMMATION 
Rapid discovery of two unprecedented meroterpenoids from Daphne altaica Pall.using molecular networking integrated with MolNetEnhancer and Network Annotation Propagation
《Chinese Chemical Letters》2024年第8期294-298,共5页Wei-Yu Zhou Zi-Han Xi Ning-Ning Du Li Ye Ming-Hao Jiang Jin-Le Hao Bin Lin Guo-Dong Yao Xiao-Xiao Huang Shao-Jiang Song 
supported by the National Natural Science Foundation of China(Nos.82073736,81872766);Science and Technology Planning Project of Liaoning Province(No.2021JH1/10400049);Liaoning revitalization talents program(Nos.XLYC2002066,XLYC2007180).
Under the guidance of the approach which integrates molecular networking,MolNetEnhancer and Net-work Annotation Propagation(NAP),daphnaltaicanoids A and B(1 and 2)with unprecedented 9-oxa-tetracyclo[6.6.1.0^(2,6).0^(8...
关键词：Daphne altaica Pall. Molecular networking MolNetEnhancer NAP Unprecedented meroterpenoid frameworks Neuroprotective activities Acetylcholinesterase inhibitors 
Phomaketals A and B,pentacyclic meroterpenoids from a eupC overexpressed mutant strain of Phoma sp.
《Chinese Chemical Letters》2024年第7期350-354,共5页Chuan Li Yangyang Han Yanan Zhai Ke Li Xingzhong Liu Zhuan Zhang Cai Jia Yongsheng Che 
financial support from the National Natural Science Foundation of China(No.82003628);the CAMS Innovation Fund for Medical Sciences(Nos.2021-I2M-1-030,2021-I2M-1-028,and 2021-1-I2M-2-002)。
Phomaketals A(1)and B(2),two tropolonic meroterpenoids with the unprecedented pentacyclic skeletons,were isolated from the solid-substrate fermentation cultures of a eupC overexpressed mutant strain of the fungus Phom...
关键词：Phoma sp. Tropolonic sesquiterpenes Biosynthetic pathways Hetero-Diels–Alder CYTOTOXICITY 
Steroids, Tri- and Meroterpenoids with a Quinone Structure—A Review
《International Journal of Organic Chemistry》2024年第1期32-68,共37页Maryam S. M. Aghaei Thies Thiemann 
Terpenoids with quinoid structures are found as natural products. This includes steroidal quinones, quinones with a secosteroid structure and meroterpenoid quinones. Importantly, catechol estrogens as endogenous metab...
关键词：STEROID Secosteroid Meroterpenoid TRITERPENOID QUINONE Anti-Tumour Agent Antibiotic Natural Product 
Divergent total synthesis of marine meroterpenoids(+)-dysidavarones A–C
《Chinese Chemical Letters》2024年第3期234-238,共5页Qunlong Zhang Yang Kuang Le Chang Jingyi Kang Bingjian Wang Chuanke Chong Zhaoyong Lu 
financially supported by the National Natural Science Foundation of China(Nos.22171146,21971121,and 22188101 to ZL);the China Postdoctoral Science Foundation(No.2021M701775 to CC)。
Here,we report a concise and divergent enantioselective total synthesis of marine sesquiterpene quinone meroterpenoids(+)-dysidavarones A–C(1–3)using predysidavarone 6 as a key common intermediate.The highly straine...
关键词：Total synthesis Natural product Dysidavarones A–C Sesquiterpene quinone Meroterpenoid 
Meroterpenoids Possessing Diverse Rearranged Skeletons with Anti-inflammatory Activity from the Mangrove-Derived Fungus Penicillium sp. HLLG-122被引量：2
《Chinese Journal of Chemistry》2023年第19期2507-2517,共11页Yu-Yue Qin Wan-Shan Li Xuan Zhang Zhang-Xin Yu Xiao-Bao Li Han-Yi Chen Yan-Ru Lv Chang-Ri Han Guang-Ying Chen 
supported by the National Natural Science Foundation of China(Nos.22177023 and 41866005);the Key Sci-ence and Technology Program of Hainan Province(No.ZDKJ202008);the Hainan Provincial Natural Science Foundation of China(221RC1054);the Specific Research Fund of the Innovation Platform for Academicians of Hainan Province(YSPTZX202030);the Innovation Platform for Academicians of Hainan Province,the Central Government Guides Local Science and Technology Devel-opment(ZY2022HN08);the research was also supported by the Innovative Research Project of Hainan Graduate Students(Qhyb2022-105).
Fifteen new meroterpenoids, littoreanoids A—O (1—15), including three rearranged skeleton meroterpenoids (1—3), were isolated from the mangrove-derived fungus Penicillium sp. HLLG-122. Compound 1 was a novel berkel...
关键词：Penicillium sp TERPENOIDS Structural elucidation Anti-inflammatory activities Conformation analysis Natural products 
A review of meroterpenoids and of their bioactivity from guava(Psidium guajava L.)被引量：2
《Journal of Future Foods》2023年第2期142-154,共13页Xinfeng Zou Haiyang Liu 
This work was financially supported by the National Natural Science Foundation of China(U1802287 and 32170408);the Ten Thousand Talents Plan of Yunnan Province for Industrial Technology Leading Talents(YNWR-CYJS-2019-011);the Project of Yunnan Characteristic Plant Screening and R&D Service CXO Platform(2022YKZY001);the State Key Laboratory of Phytochemistry and Plant Resources in West China(P2019-ZZ02).
Psidium guajava Linn.(family Myrtaceae),is commonly known as guava.Guava is consumed in large quantities throughout the world due to its ease of cultivation and high nutritional value.As an important perennial fruit t...
关键词：Psidium guajava L.(guava) PHYTOCHEMISTRY Psidium meroterpenoids Bioactivity 
Quinones from Cordia species from 1972 to 2023:isolation,structural diversity and pharmacological activities
《Natural Products and Bioprospecting》2023年第1期93-116,共24页Rostanie Dongmo Zeukang Jarmo-Charles Kalinski Babalwa Tembeni Eleonora D.Goosen Jacqueline Tembu Turibio Tabopda Kuiate Dominique Serge Ngono Bikobo Maurice Tagatsing Fotsing Alex de Théodore Atchadé Xavier Siwe-Noundou 
XS-N kindly acknowledges a National Research Foundation(NRF)Competitive Support for Unrated Researchers(CSUR)grant,Reference Number:SRUG2203291031.
Plants of the genus Cordia(Boraginaceae family)are widely distributed in the tropical regions of America,Africa,and Asia.They are extensively used in folk medicine due to their rich medicinal properties.This review pr...
关键词：CORDIA BORAGINACEAE QUINONES MEROTERPENOIDS BIOGENESIS Pharmacological activities 
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