STEROID

作品数：268被引量：720H指数：13
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Clinical Value of ABCB1 and PAI-1 Gene Polymorphisms in Predicting Glucocorticoid-induced Adverse Reactions in Nephrotic Syndrome Patients
《Current Medical Science》2024年第5期923-931,共9页Ya-ling ZHAI Shuai-gang SUN Wen-hui ZHANG Hui-juan TIAN Zhan-zheng ZHAO 
supported by the General Project of Henan Natural Science Foundation(No.232300420034);the National Natural Science Foundation of China for the Youth(No.81600555);the General Project of China Postdoctoral Science Foundation(No.2018M640684)。
Objective Glucocorticoid(GC)-induced adverse reactions(ARs)have been extensively studied due to their potential impact on patients’health.This study aimed to examine the potential correlation between two polymorphism...
关键词：adenosine triphosphate-binding cassette B1 nephrotic syndrome plasminogen activator inhibitor-1 steroid-associated avascular necrosis of the femoral head steroid diabetes 
Dosage and utilization of dexamethasone in the management of COVID-19: A critical review被引量：2
《World Journal of Virology》2024年第3期107-114,共8页Imran Sethi Asim Shaikh Musa Sethi Hira Khalid Chohan Sheraz Younus Syed A Khan Salim Surani 
BACKGROUND The severe respiratory manifestations observed in severe coronavirus disease 2019(COVID-19)cases are often associated with an excessive inflammatory response.Dexamethasone,a synthetic glucocorticoid,exerts ...
关键词：COVID-19 STEROIDS CORTICOSTEROIDS Steroid dosage Critical care Corona virus 
Multiomics approaches to uncover endometrial receptivity in embryo implantation:a mini-review
《Reproductive and Developmental Medicine》2024年第3期178-185,共8页Sudini R.Fernando Yang Yan Manish Kumar Hoi-Lam Lai Yin-Lau Lee Ernest H.Y.Ng William S.B.Yeung Kai-Fai Lee 
supported by grants from the Sanming Project of Medicine in Shenzhen,China(SZSM201612083 to W.S.B.Y.);Shenzhen Key Medical Discipline(SZXK2020089);General Research Fund,Research Grants Council,Hong Kong(06173976 and 17120720 to K.F.L.);Health and Medical Research Fund,Hong Kong(06173976 to K.F.L.);Internal Research Funding from the Department of Obstetrics and Gynecology at the University of Hong Kong.
Successful implantation requires concerted interactions during the apposition,adhesion,and invasion of the embryo into a receptive endometrium.However,the embryo implantation rate for assisted reproduction remains low...
关键词：Cell surface proteins Steroid regulation Endometrial receptivity Receptivity marker INFERTILITY 
Hemophagocytic lymphohistiocytosis triggered by relapsing polychondritis:A case report
《World Journal of Orthopedics》2024年第8期813-819,共7页Mi-Ran Han Jeong-Hwan Hwang Seungah Cha So-Yeon Jeon Kyu Yun Jang Namsu Kim Chang-Hoon Lee 
BACKGROUND Hemophagocytic lymphohistiocytosis(HLH)is a rare,life-threatening disorder caused by abnormal histiocytes and T cell activation.In adults,it is predominantly associated with infections,cancers,and autoimmun...
关键词：Hemophagocytic lymphohistiocytosis Relapsing polychondritis Autoimmune disease Fever of unknown origin STEROID Case report 
First case of fungal keratitis secondary to Yamadazyma mexicana
《International Journal of Ophthalmology(English edition)》2024年第6期1164-1167,共4页Ioannis Giachos Aristea Velegraki Sotiria Palioura 
Dear Editor,Fungal keratitis is a serious and potentially sightthreatening infection that poses a global health concern,with higher incidence rates reported in low-income countries and regions with tropical climates[1...
关键词：arise STEROID INCOME 
Human-like adrenal features in Chinese tree shrews revealed by multi-omics analysis of adrenal cell populations and steroid synthesis
《Zoological Research》2024年第3期617-632,共16页Jing-Hang Jiang Yi-Fu Wang Jie Zheng Yi-Ming Lei Zhong-Yuan Chen Yi Guo Ya-Jie Guo Bing-Qian Guo Yu-Fang Lv Hong-Hong Wang Juan-Juan Xie Yi-Xuan Liu Ting-Wei Jin Bi-Qi Li Xiao-Shu Zhu Yong-Hua Jiang Zeng-Nan Mo 
supported by the Key Research and Development Program of Guangxi(2021AB13014);Major Project of Guangxi Innovation Driven(AA18118016);National Key Research and Development Program of China(2017YFC0908000);Natural Key Research and Development Project(2020YFA0113200);National Natural Science Foundation of China(81770759,82060145,31970814);Natural Science Foundation of Guangxi Zhuang Autonomous Region(2021JJA140912);Advanced Innovation Teams and Xinghu Scholars Program of Guangxi Medical University,Guangxi Key Laboratory for Genomic and Personalized Medicine(19-050-22,19-185-33,20-065-33,22-35-17);Major Project of Scientific Research and Technology Development Plan of Nanning(20221023);Guangxi Natural Science Foundation(2022GXNSFAA035641);Self-funded Project of Health Commission of Guangxi Zhuang Autonomous Region(Z-A20230620)。
The Chinese tree shrew(Tupaia belangeri chinensis)has emerged as a promising model for investigating adrenal steroid synthesis,but it is unclear whether the same cells produce steroid hormones and whether their produc...
关键词：Tree shrew Adrenal gland DEHYDROEPIANDROSTERONE Genome-wide association studies Disease model 
A fungal CYP from Beauveria bassiana with promiscuous steroid hydroxylation capabilities
《Chinese Chemical Letters》2024年第5期218-222,共5页Yu Peng Yue Wang Tian-Jiao Chen Jing-Jing Chen Jin-Ling Yang Ting Gong Ping Zhu 
supported by the National Key Research and Development Program of China(Nos.2020YFA0908003 and 2018YFA0901900);CAMS Innovation Fund for Medical Sciences(No.CIFMS2021-I2M-1-029).
Hydroxylation of steroid core is critical to the synthesis of steroid drugs.Direct sp^(3) C-H hydroxylation is challenging through chemical catalysis,alternatively,fungal biotransformation offers a possible solution t...
关键词：Fungal CYPs Steroid hydroxylase Beauveria bassiana Promiscuous biocatalyst Molecular dynamics 
Steroids, Tri- and Meroterpenoids with a Quinone Structure—A Review
《International Journal of Organic Chemistry》2024年第1期32-68,共37页Maryam S. M. Aghaei Thies Thiemann 
Terpenoids with quinoid structures are found as natural products. This includes steroidal quinones, quinones with a secosteroid structure and meroterpenoid quinones. Importantly, catechol estrogens as endogenous metab...
关键词：STEROID Secosteroid Meroterpenoid TRITERPENOID QUINONE Anti-Tumour Agent Antibiotic Natural Product 
Editorial Commentary:Association of Comorbid Asthma and the Efficacy of Bioabsorbable Steroid-eluting Sinus Stents Implanted after Endoscopic Sinus Surgery in Patients with Chronic Rhinosinusitis with Nasal Polyps
《Current Medical Science》2023年第6期1258-1259,共2页Xin LUO Xue-kun HUANG Ya-na ZHANG Qin-tai YANG 
Chronic rhinosinusitis with nasal polyps(CRSw-NP)is a multifactorial and heterogeneous disorder of the sinonasal mucosa,characterized by a high relapse rate after medical and surgical treatments[1].Endoscopic sinus su...
关键词：Surgery operative treatment 
Postoperative mometasone irrigations improve quality of life in skull base tumor patients
《World Journal of Otorhinolaryngology-Head and Neck Surgery》2023年第4期314-319,共6页Mandy K.Salmon Rijul S.Kshirsagar Jacob G.Eide Auddie M.Sweis Kathleen Davin Aman Prasad Heather Ungerer Elizabeth Stevens Kevin Ig‐Izevbekhai Siddhant Tripathi Tran B.Locke Theodore Lin Brian M.Sweis Michael A.Kohanski Nithin D.Adappa James N.Palmer 
Objectives:The use of topical corticosteroids to manage postoperative sinonasal symptoms after endoscopic skull base surgery (ESBS) has not been well studied.We quantified long‐term impact of postoperative steroid ir...
关键词：postoperative steroid irrigations skull base tumors 
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