BACKGROUND Duchenne muscular dystrophy(DMD)is a severe lethal X-linked monogenic recessive congenital muscular dystrophy caused by various types of mutations in the dystrophin gene(DG).It is one of the most common hum...
BACKGROUND Posterior reversible encephalopathy syndrome(PRES)is a complex neurological disorder characterized by symptoms such as headaches,seizures,confusion,and visual disturbances.The pathophysiology of PRES involv...
Background Sudden sensorineural hearing loss(SSNHL)is a rapid condition of hearing impairment,typically occurring over 72 hours and affecting the inner ear or auditory nerve pathways.The etiology of SSNHL remains larg...
Background: Patients with Steroid-Refractory Idiopathic Minimal change disease (SRIM) have high morbidity and mortality and inherent side effects of immunosuppressive therapy. Except for its cost, R has been shown to ...
Introduction: The nephrotic syndrome (NS) is the most common glomerular nephropathy in children. The aim of this work was to study the diagnostic and evolutionary aspects of NS in pediatrics at the national Hospital o...
Aplastic anemia (AA) is a rare, life-threatening disease characterized by pancytopenia and bone marrow failure. However, since the introduction of immunosuppressive therapy and allogeneic stem cell transplantation, ou...
Background: Previous studies suggested that the focal and segmental nature of focal segmental glomerulosclerosis (FSGS) may lead to sample error or diagnosis error that results in minimal change disease (MCD) misdiagn...
Introduction: Intramuscular depot betamethasone treatment had resulted in a significant improvement among fibromyalgia patients with elevated C-reactive protein (C-RP) levels. Here, we wanted to evaluate the same regi...
supported by grants from the National Natural Science Foundation of China(Nos.82270233,81830004 and 82070168);National Natural Science Foundation of China Youth Science Foundation Project(No.82200246);Translational Research Grant of NCRCH(No.2020ZKZC04);National Key R&D Program of China(No.2021YFA1100800);Shanghai Municipal Health Commission(No.2020CXJQ02).
Clinical question What are the recommendations for the timing,dosage,and usage of corticosteroids during cytokine release syndrome(CRS)caused by chimeric antigen receptor(CAR)-T cell therapy for hematologic malignancies?
Introduction: Corticosteroid therapy used in rheumatology is effective but can lead to complications. The objective was to describe the complications of corticosteroid therapy in rheumatological practice at Ignace Dee...