National Resources Center for Non Human Primates;National Key R&D Project of China,Grant/Award Number:2021YFF0702804。
Background:Non-human primates(NPHs),such as rhesus macaques,cynomol-gus monkeys,and Assamese macaques,play a crucial role in biomedical research.However,baseline cytokine and electrolyte data for these three species,p...
Extracorporeal therapies have a definite role in patients with acute liver failure,acute on-chronic liver failure,and progressive chronic liver disease.They act as a bridge-to-transplant in these patients.With the inc...
supported by a National Key Research and Development Project Grant(2021YFC2300502);the National Natural Science Foundation of China Grants(32370930 and 32360176).
Leucine-rich repeat kinase 2(Lrrk2)has received widespread attention as a risk gene associated with Parkinson’s disease.As the immune response attributes of Parkinson’s disease have been gradually revealed,the link ...
Mycoplasma pneumoniae(M.pneumoniae)is a common pathogen that causes community-acquired pneumonia in children.The clinical presentation of this pathogen can range from mild self-limiting illness to severe and refractor...
supported by the China Scholarship Council(No.202306320511);by the BSMU Strategic Academic Leadership Program PRIORITY-2030.
With increasing incidence and geography,cancer is one of the leading causes of death,reduced quality of life and disability worldwide.Principal progress in the development of new anticancer therapies,in improving the ...
supported by Deutsche Forschungsgemeinschaft(German Research Foundation)under Germany's Excellence Strategy(EXC2151,390873048)。
In a recent article published in Science,Szeto et al.identified myocyte-specific enhancer factor 2d(Mef2d)as a promoter of type 2 immunity and allergic lung inflammation.Using CRISPR screens and orthogonal recombinase...
2023 Undergraduate Innovation and Entrepreneurship Training Program of Tibet Minzu University(Autonomous Region Project Level)“The Effect of Hypoxia on the Differentiation of Intestinal Mucosal Dendritic Cells in a Mouse Model of Colitis”(Project No.S202310695105);In-House Research Project of Tibet Minzu University“The Effect and Mechanism of Tibetan Medicine Renqing Changjue on EGF Expression in the Gastric Mucosa of CAG Rats”(Project No.21MDY03)。
Ulcerative colitis(UC)is a chronic intestinal inflammatory disease with complex causes that are closely associated with environmental,genetic,and immune factors.However,the precise etiology and pathogenesis remain und...
Background:The benefits of exercise are well known;however,many of the underlying molecular mechanisms are not fully understood.Skeletal muscle secretes myokines,which mediate muscleorgan crosstalk.Myokines regulate s...
Natural Science Foundation of Chongqing(2022NSCQ-MSX2319 to Dr.Huili Lu,China);Science&Technology Commission of Shanghai Municipality(Nos.21S11906300 and 23ZR1431800 to Dr.Huili Lu,China).
Immunocytokines,employing targeted antibodies to concentrate cytokines at tumor sites,have shown potential advantages such as prolonged cytokine half-lives,mitigated adverse effects,and synergistic antitumor efficacy ...
Correction to:Signal Transduction and Targeted Therapy https://doi.org/10.1038/s41392-024-01934-w,published online 21 August 2024 After online publication of the Article,1 the authors received feedback from a reader t...