supported by The Basic Science Research Program through the National Research Foundation of Korea(NRF);funded by the Ministry of Education(RS-2023-00244901)(to RB)。
Challenges in the prevention and treatment of mild cognitive impairment associated with Alzheimer's disease:Increased life expectancy due to advancements in medical care has given rise to an aging population,accompani...
Background:The benefits of exercise are well known;however,many of the underlying molecular mechanisms are not fully understood.Skeletal muscle secretes myokines,which mediate muscleorgan crosstalk.Myokines regulate s...
This project was supported by the University Collaborative Research Program and Faculty of Science Collaborative Grant-University of Manitoba.
Purpose The purpose of this study was to examine the response of myokines to blood-flow restricted resistance-exercise(BFR-RE)in younger and older males before and after completing a 12-week resistance-training progra...
In the past decades,skeletal muscle has become the focus of numerous studies due to its potential physiological role as an endocrine organ secreting hundreds of myokines.Among these myokines,fibroblast growth factor 2...
Recently, glucagon-like peptide-1(GLP-1) receptor agonists have become a cornerstone for the treatment of obese patients with type 2 diabetes(T2D), exhibiting favorable effects on the cardiovascular outcome. In T2D, i...
supported by a Natural Sciences and Engineering Research Council of Canada (NSERC) Discovery Grant (No. RGPIN 435807-13) to JPL;the ANZ-MASON foundation (to DB);supported by a Canadian Institutes of Health Research (CIHR) New Investigator Award (No. MSH-141980)
Background: Exercise promotes numerous phenotypic adaptations in skeletal muscle that contribute to improved function and metabolic capacity. An emerging body of evidence suggests that skeletal muscle also releases a ...
supported by National Basic Research Program of China (2012CB124704,2013CB127305);National Nature Science Foundation of China (31372325,31110103909, 31330075);Key Projects in the National Science & Technology Pillar Program (2013BAD21B04);The Chinese Academy of Science STS Project (KFJ-EW-STS-063)
Interleukin-15(IL-15) is a cytokine highly expressed in skeletal muscle. The objective of the present study was to investigate the development of muscle IL-15 expression in suckling piglets and in early weaning piglet...
Excess body weight constitutes a worldwide health problem with epidemic proportions impacting on the risk and prognosis of several disease states including malignancies. It is believed that the metabolic changes assoc...