Recommendations for the timing,dosage,and usage of corticosteroids during cytokine release syndrome(CRS)caused by chimeric antigen receptor(CAR)-T cell therapy for hematologic malignancies  

作　　者：Sanfang Tu Xiu Luo Heng Mei Yongxian Hu Yang Liu Ping Li Dehui Zou Ting Niu Kailin Xu Xi Zhang Lugui Qiu Lei Gao Guangxun Gao Li Zhang Yimei Feng Ying Wang Mingfeng Zhao Jianqing Mi Ming Hou Jianmin Yang He Huang Jianxiang Wang Yu Hu Weili Zhao Depei Wu Jun Ma Yuhua Li Wenbin Qian Xiaojun Huang Weidong Han Aibin Liang 

机构地区：[1]Department of Hematology,Zhujiang Hospital,Southern Medical University,Guangzhou,Guangdong 510280,China [2]Department of Hematology,Tongji Hospital,Tongji University School of Medicine,Shanghai 200065,China [3]Institute of Hematology,Union Hospital of Tongji Medical College,Huazhong University of Science and Technology,Wuhan,Hubei 430022,China [4]Center for Bone Marrow Transplantation,The First Affiliated Hospital,School of Medicine,Zhejiang University,Hangzhou,Zhejiang 310058,China [5]Department of Bio-therapeutic,Chinese PLA General Hospital,Beijing 100853,China [6]State Key Laboratory of Experimental Hematology,National Clinical Research Center for Blood Diseases,Institute of Hematology&Blood Disease Hospital,Chinese Academy of Medical Sciences&Peking Union Medical College,Tianjin 300020,China [7]Department of Hematology,West China Hospital,Sichuan University,Chengdu,Sichuan 610041,China [8]Department of Hematology,The Affiliated Hospital of Xuzhou Medical University,Xuzhou,Jiangsu 221006,China [9]Medical Center of Hematology,Xinqiao Hospital of Army Medical University,Chongqing 400037,China [10]Department of Hematology,Xijing Hospital,Air Force Medical University,Xi’an,Shaanxi 710000,China [11]Tianjin First Central Hospital,The First Affiliated Central Hospital of Nankai University,The First Central Clinical College of Tianjin Medical University,Tianjin 300192,China [12]Department of Hematology,Shanghai Ruijin Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200025,China [13]Department of Hematology,Qilu Hospital of Shandong University,Shandong University,Jinan,Shandong 250012,China [14]Department of Hematology,Changhai Hospital,The Naval Medical University,Shanghai 200433,China [15]Shanghai Institute of Hematology,State Key Laboratory of Medical Genomics,National Research Center for Translational Medicine at Shanghai,Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine,Shanghai 200025,China [16]National Clinical Research Center for Hematologic Diseases,Jiangsu

出　　处：《Chinese Medical Journal》2024年第22期2681-2683,共3页中华医学杂志(英文版)

基　　金：supported by grants from the National Natural Science Foundation of China(Nos.82270233,81830004 and 82070168);National Natural Science Foundation of China Youth Science Foundation Project(No.82200246);Translational Research Grant of NCRCH(No.2020ZKZC04);National Key R&D Program of China(No.2021YFA1100800);Shanghai Municipal Health Commission(No.2020CXJQ02).

摘　　要：Clinical question What are the recommendations for the timing,dosage,and usage of corticosteroids during cytokine release syndrome(CRS)caused by chimeric antigen receptor(CAR)-T cell therapy for hematologic malignancies?

关 键 词：CYTOKINE CRS CAR 

分 类 号：R73[医药卫生—肿瘤]