DEHYDROEPIANDROSTERONE

作品数：28被引量：58H指数：4
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相关领域：医药卫生更多>>
相关作者：伏静更多>>
相关机构：上海集爱遗传与不育诊疗中心北京协和医学院北京大学复旦大学更多>>
相关期刊：《Open Journal of Psychiatry》《Current Medical Science》《Acta Biochimica et Biophysica Sinica》《Burns & Trauma》更多>>
相关基金：国家自然科学基金湖北省自然科学基金上海市浦江人才计划项目国家重点基础研究发展计划更多>>
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Human-like adrenal features in Chinese tree shrews revealed by multi-omics analysis of adrenal cell populations and steroid synthesis
《Zoological Research》2024年第3期617-632,共16页Jing-Hang Jiang Yi-Fu Wang Jie Zheng Yi-Ming Lei Zhong-Yuan Chen Yi Guo Ya-Jie Guo Bing-Qian Guo Yu-Fang Lv Hong-Hong Wang Juan-Juan Xie Yi-Xuan Liu Ting-Wei Jin Bi-Qi Li Xiao-Shu Zhu Yong-Hua Jiang Zeng-Nan Mo 
supported by the Key Research and Development Program of Guangxi(2021AB13014);Major Project of Guangxi Innovation Driven(AA18118016);National Key Research and Development Program of China(2017YFC0908000);Natural Key Research and Development Project(2020YFA0113200);National Natural Science Foundation of China(81770759,82060145,31970814);Natural Science Foundation of Guangxi Zhuang Autonomous Region(2021JJA140912);Advanced Innovation Teams and Xinghu Scholars Program of Guangxi Medical University,Guangxi Key Laboratory for Genomic and Personalized Medicine(19-050-22,19-185-33,20-065-33,22-35-17);Major Project of Scientific Research and Technology Development Plan of Nanning(20221023);Guangxi Natural Science Foundation(2022GXNSFAA035641);Self-funded Project of Health Commission of Guangxi Zhuang Autonomous Region(Z-A20230620)。
The Chinese tree shrew(Tupaia belangeri chinensis)has emerged as a promising model for investigating adrenal steroid synthesis,but it is unclear whether the same cells produce steroid hormones and whether their produc...
关键词：Tree shrew Adrenal gland DEHYDROEPIANDROSTERONE Genome-wide association studies Disease model 
Vitamin E modulates androgen receptor gene expression to attenuate ovarian dysfunctions in a rat model of dehydroepiandrosterone-induced polycystic ovary
《Asian pacific Journal of Reproduction》2023年第2期81-89,共9页Olugbemi T Olaniyan Ayobami Dare Charles O.Adetunji Gloria E.Okotie Joseph B.Dare Bosun M.Adigun Femi Adebayo 
Objective:To investigate the protective effect of vitamin E in dehydroepiandrosterone(DHEA)-induced polycystic ovary in rats.Methods:Premature female Wistar rats were randomly allocated into four groups,with 7 rats in...
关键词：DEHYDROEPIANDROSTERONE Metabolic markers Polycystic ovarian syndrome Vitamin E Wistar rats 
Dehydroepiandrosterone sulfate supplementation in health and diseases
《World Journal of Meta-Analysis》2023年第4期102-111,共10页Parth Jethwani Ashu Rastogi Ravindra Shukla 
Dehydroepiandrosterone sulfate(DHEAS)is a hormone produced by the zona reticularis of the adrenal gland and the ovaries.Initially considered as an inert compound merely serving as an intermediate in the conversion of ...
关键词：DEHYDROEPIANDROSTERONE ADRENAL Health supplements HYPOTHYROIDISM AUTOIMMUNITY DEPRESSION Cardiovascular disease 
Screening of novel synthetic derivatives of dehydroepiandrosterone for antivirals against flaviviruses infections
《Virologica Sinica》2022年第1期94-106,共13页Muhammad Imran Luping Zhang Bohan Zheng Zikai Zhao Dengyuan Zhou Shengfeng Wan Zheng Chen Hongyu Duan Qiuyan Li Xueqin Liu Shengbo Cao Shaoyong Ke Jing Ye 
supported by National Key Research and Development Program of China(2016YFD0501102,2016YFD0500407);National Natural Science Foundation of China(31825025,32022082,32030107,32002268);Fundamental Research Funds for the Central Universities(2662018QD025);Natural Science Foundation of Hubei Province(2019CFA010)
Flaviviruses are important arthropod-borne pathogens that represent an immense global health problem.Their unprecedented epidemic rate and unpredictable clinical features underscore an urgent need for antiviral interv...
关键词：FLAVIVIRUSES Japanese encephalitis virus(JEV) Zika virus(ZIKV) Dehydroepiandrosterone(DHEA) ANTIVIRALS 
Components of the human-specific,p53-mediated“kill switch”tumor suppression mechanism are usurped by human tumors,creating the possibility of therapeutic exploitation
《Cancer Drug Resistance》2019年第4期1207-1214,共8页Jonathan Nyce 
This work was supported in part by the U.S.Food&Drug Administration(FDA)(G002126-C-2195-SR1891,G003126-C-2195-SR1892,G003126-C-2195-SR1893,G003126-C-2195-SR1894,G003126-C-2195-SR1895).
We recently reported our detection of an anthropoid primate-specific,adrenal androgen-dependent,“kill switch”tumor suppression mechanism that is triggered by the inactivation of the p53 tumor suppressor.This mechani...
关键词：P53 TP53 DEHYDROEPIANDROSTERONE dehydroepiandrosterone sulfate 
Kidney-Qi deficiency diagnosed by Deng's diagnosis standard was not correlated with aging based on clinical observation of 90 participants
《Journal of Traditional Chinese Medicine》2019年第2期267-274,共8页Zhao Zhengxiao Liu Lumei Tang Zihui Mohammadtursun Nabijan Lu Linwei Li Mihui Lü Yibao Mo Shuming Ma Wenjuan Wang Meng Wei Ying Gong Weiyi Dong Jingcheng 
Supported by Shanghai Municipal Commission of Health and Family Planning Project:Preliminary Study on the Construction of Asthma Integrative Medicine Management Platform based on Smart Devices and Mobile Internet(No.ZYKC201602001)
OBJECTIVE: To verify the Traditional Chinese Medicine(TCM) theory that kidney-Qi deficiency(KQD)is considered to be the main cause of aging using cross-sectional study.METHODS: Demographic and lifestyle characteristic...
关键词：AGING Kidney-Qi deficiency Advanced oxidation protein products MALONDIALDEHYDE DEHYDROEPIANDROSTERONE sulfate Cross-sectional studies 
Role of Dehydroepiandrosterone Supplementation in Improving Intracytoplasmic Sperm Injection Outcome for Women with Expected Poor Ovarian Response
《Open Journal of Obstetrics and Gynecology》2019年第3期353-362,共10页Abd El-Naser Abd El-Gaber Ali Mustafa M. Khodry 
Background: As regard to adjuvant supplementations, nowadays dehydroepiandrosterone (DHEA) is widely used all over the world and is considered to be a potential agent to ameliorate the assisted reproduction technologi...
关键词：DEHYDROEPIANDROSTERONE (DHEA) INTRACYTOPLASMIC SPERM Injection (ICSI) Poor OVARIAN Response (POR) 
Dehydroepiandrosterone:a potential therapeutic agent in the treatment and rehabilitation of the traumatically injured patient被引量：3
《Burns & Trauma》2019年第1期248-260,共13页Conor Bentley Jon Hazeldine Carolyn Greig Janet Lord Mark Foster 
the National Institute for Health Research Surgical Reconstruction and Microbiology Research Centre,which is jointly funded by the Department of Health and Ministry of Defence(www.nihr.ac.uk).
Severe injuries are the major cause of death in those aged under 40,mainly due to road traffic collisions.Endocrine,metabolic and immune pathways respond to limit the tissue damage sustained and initiate wound healing...
关键词：DEHYDROEPIANDROSTERONE Dehydroepiandrosterone sulphate Traumatic injury Intensive care IMMUNE REHABILITATION 
Effects of Ziyin Jianghuo Ningxin decoction plus dehydroepiandrosterone and femoston in treatment of patients with menopausal symptoms被引量：6
《Journal of Traditional Chinese Medicine》2018年第5期787-796,共10页Lin Jing Zhu Jun Tian Fubo Chen Lanting Zhang Yang Wang Yan Wang Mingyan Hans-Jurgen Gober Li Da-jin Wang Ling 
Supported by the National Natural Science Foundation of China(No.31571196);the Science and Technology Commission of Shanghai Municipality 2015 YIXUEYINGDAO project(No.15401932200);the FY2008 JSPS Postdoctoral Fellowship for Foreign Researchers P08471;the National Natural Science Foundation of China(No.30801502);the Shanghai Pujiang Program(No.11PJ1401900);Development Project of Shanghai Peak Disciplines-Integrative Medicine(No.20150407)
OBJECTIVE: To determine the therapeutic effect of Ziyin Jianghuo Ningxin Decoction(ZYJHNXD) plus dehydroepiandrosterone(DHEA) and menopausalhormone therapy(MHT) in patients suffering from menopausal symptoms identifie...
关键词：MENOPAUSAL SYMPTOMS MENOPAUSAL HORMONE THERAPY Femoston Ziyin Jianghuo Ningxin DECOCTION DEHYDROEPIANDROSTERONE 
MIF May Participate in Pathogenesis of Polycystic Ovary Syndrome in Rats through MAPK Signalling pathway被引量：10
《Current Medical Science》2018年第5期853-860,共8页Dan-ni ZHOU Sai-jiao LI Jin-li DING Tai-lang YIN Jing YANG Hong YE 
This project was in part supported by the National Natural Science Foundation of China (No.30973196).
The polycystic ovary syndrome (PCOS) model was established in fats and correlation between the expression of macrophage migration inhibitory factor (MIF) and cytokinesis with the MAPK signalling pathway in the rat ova...
关键词：POLYCYSTIC OVARY syndrome HIGH-FAT diet DEHYDROEPIANDROSTERONE migration inhibitory factor MAPK signalling pathway RATS 
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