HIGH-FAT

作品数：91被引量：310H指数：10
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Oat avenanthramide B alleviates high-fat diet-induced obesity via regulating fatty acid metabolism involved in gut bacteria and fungi remodeling
《Food Science and Human Wellness》2025年第2期769-781,共13页Yongyong Liu Kai Huang Xiao Guan Sen Li Hongdong Song Ying Zhang Yu Zhang Zhu Sun Zhiquan Yu 
financially supported by the Major Project of Inner Mongolia Science and Technology Department,China(2021ZD0002);National Natural Science Foundation of China,China(32202054);Project Supported by the Shanghai Committee of Science and Technology,China(20DZ2202700)。
Oat avenanthramides(AVNs)have been found to exhibit novel lipid-lowering effects.However,the mechanism remains unclear.In this study,the effect of avenanthramide B(AVN B),as one of the major AVNs,on highfat diet(HFD)-...
关键词：Avenanthramide B High-fat diet Fatty acid metabolism Ileal lipid absorption Gut bacteria and fungi 
Establishment of a non-alcoholic fatty liver disease model by high fat diet in adult zebrafish
《Animal Models and Experimental Medicine》2024年第6期904-913,共10页Xiang Li Lei Zhou Yuying Zheng Taiping He Honghui Guo Jiangbin Li Jingjing Zhang 
the Discipline Construction Project of Guangdong Medical University;Grant/Award Number:4SG22258G;the Science and Technology Planning Project of Zhanjiang;China;Grant/Award Number:2022A01231。
Background:Non-alcoholic fatty liver disease(NAFLD)has become the most common chronic liver disease in recent years,but the pathogenesis is not fully understood.Therefore,it is important to establish an effective anim...
关键词：ER stress high-fat-diet METABOLISM non-alcoholic fatty liver disease ZEBRAFISH 
Polysaccharide-rich extract of Potentilla anserina ameliorates nonalcoholic fatty liver disease in free fatty acid-induced HepG2 cells and high-fat/sugar diet-fed mice
《Food Science and Human Wellness》2024年第6期3351-3360,共10页Xiujun Lin Yimei Zheng Yingying Yan Hongting Deng Shunxin Wang Yuanju He Yuting Tian Wenhui Zhang Hui Teng 
supported by the Natural Science Foundation of Tibet Autonomous Region(XZ202201ZR0012G);Quality Evaluation and Efficient Utilization of Effective Components of Potentilla anserine Resources in Tibet(XZ202201ZD0001N).
Potentilla anserina L.(PA)belongs to the Rosaceae family,is a common edible plant in the Qinghai-Tibet Plateau areas of China.This study elucidates the mechanism upon which crude polysaccharide of PA(PAP)on fat accumu...
关键词：Potentilla anserina L. Non-alcoholic fatty liver disease Lipid accumulation HepG2 cells High fat diet 
Effects of axylitol-casein complex on insulin resistance and gut microbiota composition in high-fat-diet+streptozotocin-induced type 2 diabetes mellitus mice
《Food Science and Human Wellness》2024年第5期2741-2753,共13页Fanhua Kong Juan Zhang Shimo Kang Xinyu Shen Aicheng Liu Yan Zheng Junhua Shao Xiqing Yue 
supported by the “Thirteenth Five Year” National Science and Technology Plan Project of China (2018YFC1603703,2018YFC1604302);National Natural Science Foundation of China (2013BAD18B03);Shenyang Technological Innovation Project (Y170-028);LiaoNing Revitalization Talents Project (XLYC1902083)
This study investigated the effects of a xylitol-casein non-covalent complex(XC)on parameters related to type 2 diabetes mellitus(T2DM),in addition to related changes in gut microbiome composition and functions.High-f...
关键词：Xylitol-casein complex Type 2 diabetes mellitus Insulin resistance Gut microbiota 
High temperature ameliorates high-fat diet-induced obesity by promoting ceramide breakdown in skeletal muscle tissue
《Life Metabolism》2024年第5期1-16,共16页Qiankun Wang Lupeng Chen Junzhi Zhang Yue Liu Yi Jin Jian Wu Zhuqing Ren 
supported by the National Natural Science Foundation of China(32172700);the Fundamental Research Funds for the Central Universities(2662023DKPY003 and 2662022DKPY002).
Obesity is considered an epidemic often accompanied by insulin resistance(IR).Heat treatment(HT)has been shown to prevent high-fat diet-induced IR in skeletal muscle,but the underlying mechanisms are poorly understood...
关键词：high temperature OBESITY insulin resistance ceramide breakdown lipid droplets 
Effects of High-Intensity Intermittent Training on Metabolic Parameters and Irisin Levels in High-Fat-Fed Rats
《Journal of Clinical and Nursing Research》2024年第8期52-59,共8页Dongping Tan Wenbin Zhang Longxia Zheng Huijun Lin 
2021 Guangdong Province Ordinary University Characteristics Class Project(Natural Science)(Project No.2021ktscx256);2023 Guangdong Science and Technology Innovation Strategy Special Fund Project(Project No.pdjh2023a0896);Guangdong Sports Vocational and Technical College in 2024 University Curriculum Education Demonstration Projects-Sports Training“Course Education”(Project No.2024szsftd01)。
Objective:To investigate the effects of high-intensity intermittent training(HIIT)on preventing significant weight gain and provide scientific theoretical support and practical guidance for reducing the occurrence of ...
关键词：High intensity interval training RATS Metabolic characterization Irisin 
Macrophage-specific FGFR1 deletion alleviates high-fat-diet-induced liver inflammation by inhibiting the MAPKs/TNF pathways被引量：1
《Acta Pharmacologica Sinica》2024年第5期988-1001,共14页Yan-ni Zhao Zhou-di Liu Tao Yan Ting-xin Xu Tian-yang Jin Yong-sheng Jiang Wei Zuo Kwang Youl Lee Li-jiang Huang Yi Wang 
support was provided by the Medical and Health Science Research Project of Zhejiang Province(2023XY164 to LJH,2022KY348 to WZ);Key Research Project of Wenzhou City(ZY2021021 to YW).
Non-alcoholic fatty liver disease(NAFLD)is a common metabolic disease that is substantially associated with obesity-induced chronic inflammation.Macrophage activation and macrophage-medicated inflammation play crucial...
关键词：non-alcoholic fatty liver disease fibroblast growth factor receptor 1 MACROPHAGES MAPKS NF-κB hepatic stellate 
Chronic Real-Ambient PM_(2.5)Exposure Exacerbates Cardiovascular Risk via Amplifying Liver Injury in Mice Fed with a High-Fat and High-Cholesterol Diet被引量：1
《Environment & Health》2024年第4期221-232,共12页Yi Chen Hiu Lok Ngan Yuanyuan Song Zenghua Qi Lifang Zhao Chuan Dong Ruijin Li Yanbo Li Zhu Yang Zongwei Cai 
supported by National Key Research and Development Program of China(2018YFA0901104);National Natural Science Foundation of China(91843301);Hong Kong General Research Fund(12302922,12303320,and 12103820);internal research funds SKLP_2223_P04 from Hong Kong Baptist University.
Epidemiology has associated fine particulate matter(PM_(2.5))exposure with an increased cardiovascular risk.However,the underlying mechanism,particularly from the liver perspective,remains unclear.Here,the influence o...
关键词：PM_(2.5) HFCD Metabolomics LIPIDOMICS Cardiovascular risk 
Alisol B 23-acetate promotes white adipose tissue browning to mitigate high-fat diet-induced obesity by regulating mTOR-SREBP1 signaling被引量：2
《Journal of Integrative Medicine》2024年第1期83-92,共10页Lu-lu Han Xin Zhang Hui Zhang Ting Li Yi-chen Zhao Ming-hui Tian Feng-lei Sun Bo Feng 
supported by Shandong Provincial Natural Science Foundation General Program(No.ZR2022MH213);Shandong Provincial Traditional Chinese Medicine Science and Technology Project General Program(No.M2023241);Jinan Clinical Medical Science and Technology Innovation Program(No.202328013);Qinghai Province High-end Innovative Talents Thousand Talents Program.
Objective Obesity is a global health concern with management strategies encompassing bariatric surgery and anti-obesity drugs;however,concerns regarding complexities and side effects persist,driving research for more ...
关键词：OBESITY Alisol B 23-acetate Adipose tissue mTOR-SREBP1 High-fat diet 
Perilipin 2 inhibits replication of hepatitis B virus deoxyribonucleic acid by regulating autophagy under high-fat conditions
《World Journal of Virology》2024年第1期1-4,共4页M Victoria Delpino Jorge Quarleri 
Hepatitis B virus(HBV)infection poses a global health concern without a definitive cure;however,antiviral medications can effectively suppress viral replication.This study delves into the intricate interplay between l...
关键词：Perilipin 2 Hepatitis B virus Non-alcoholic fatty liver disease Liver AUTOPHAGY 
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