LIPIDOMICS

作品数：98被引量：190H指数：7
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相关领域：医药卫生生物学更多>>
相关作者：杨丽白玉刘虎威更多>>
相关机构：江西中医药大学华中科技大学广东药科大学北京大学更多>>
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相关基金：国家自然科学基金中国博士后科学基金广东省自然科学基金高等学校学科创新引智计划更多>>
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Volatile flavor analysis of flesh oil and liver oil from Doederleinia berycoides based on HS-GC-IMS,HS-SPME-GC-MS and lipidomics
《Grain & Oil Science and Technology》2025年第1期1-12,共12页Feifan Wu Kewei Lin Jixiang Zhang Xinyang Li Xiaoguo Ying Shanggui Deng Alessandra Guidi Gengsheng Xiao Feng Wang Lukai Ma 
supported by the R&D Projects in Key Areas of Guangdong Province(2023B0202080003);the National Natural Science Foundation of China(32472272,32302135,32072291);“Pioneer”and“Leading Goose”R&D Program of Zhejiang(2023C02006);Youth S&T Talent Support Programme of Guangdong Provincial Association for Science and Technology(SKXRC202401)。
Edible oils derived from aquatic products are rich in lipids beneficial to human health.However,the volatile flavor characteristics of flesh oil and liver oil from Doederleinia berycoides remain unclear.In this study,...
关键词：Flesh oil Liver oil LIPIDS Volatile compounds Volatile flavors 
Integrating lipidomics and gut microbiota to study the anti-hyperlipidemia effect of Sargentodoxae Caulis extract
《Traditional Medicine Research》2025年第1期1-11,共11页Xiao-Xiao Zhang Li Jia Xiu-Jun Zhan Charity Ngina Qing-Rui Zhang Xiao-Ge Li Qi-Bao Jiang Shi Bai Miao-Miao Jiang 
supported by the Science and Technology Program of Tianjin in China(No.23ZYJDSS00030);the Public Applied Technology Research Project of Zhejiang Province(No.LGD22H090010)。
Background:Sargentodoxae Caulis(SC)is the vine stem of Sargentodoxa Cuneata(Oliv.)Rehd.&E.H.Wilson in C.S.Sargent,and it in traditional Chinese medicine has been known for promoting blood circulation and removing bloo...
关键词：HYPERLIPIDEMIA Sargentodoxae Caulis LIPIDOMICS intestinal flora 
Chemistry-driven mass spectrometry for structural lipidomics at the C=C bond isomer level
《Chinese Chemical Letters》2025年第1期225-233,共9页Junmeng Luo Qiongqiong Wan Suming Chen 
financially supported by the National Natural Science Foundation of China(No.22074111);National Key Research and Development Program of China(No.2021YFC2700700);the Opening fund of Hubei Key Laboratory of Bioinorganic Chemistry&Materia Medica(No.BCMM202303)。
As more and more studies have shown that lipid molecules play an important role in the whole biology,in-depth analysis of lipid structure has become particularly important in lipidomics.Mass spectrometry(MS),as the pr...
关键词：Mass spectrometry Structural lipidomics Lipid isomers Double bond location Double bond configuration Chemical derivatization 
Dietary carbohydrate to lipid ratio affects growth,reproductive performance and health of female yellow catfish(Pelteobagrus fulvidragrus):A lipidomics analysis
《Animal Nutrition》2024年第4期429-441,共13页Shuzhan Fei Zheng Chen Haokun Liu Junyan Jin Yunxia Yang Dong Han Xiaoming Zhu Shuoqi Xie 
supported by the National Key Research and Development Programof China(2022YFD2400900);the earmarked fund for China Agriculture Research System(CARS-46).
This study aimed to examine the impact of dietary carbohydrate to lipid(CHO/L)ratio on the growth,reproductive,and offspring performance of broodstock yellow catfish,and to elucidate the metabolic differences between ...
关键词：Yellow catfish CARBOHYDRATE LIPID Reproductive performance LIPIDOMICS 
Coal Worker’s Pneumoconiosis-Targeted Lipidomics Reveals Aberrant Phospholipid Metabolism for Early-Stage Diagnosis
《China CDC weekly》2024年第52期1410-1416,I0004,I0005,共9页Yuzhen Feng Jing Dai Junyun Wang Fangda Peng Wenrong Wang Xiao Yu Xiaomei Kong Qingjun Qian Qicai Liu Huanqiang Wang Chunguang Ding Yiwei Shi 
Introduction:Pneumoconiosis is the most prevalent occupational disease in China,with coal worker pneumoconiosis(CWP)demonstrating the highest incidence.Studies have indicated that phospholipids may be associated with ...
关键词：LIPID ELEVATED initially 
Expansion Strategy-Driven Micron-Level Resolution Mass Spectrometry Imaging of Lipids in Mouse Brain Tissue
《CCS Chemistry》2024年第11期2662-2670,共9页Yik Ling Winnie Hung Chengyi Xie Jianing Wang Xin Diao Ruxin Li Xiaoxiao Wang Shulan Qiu Jiacheng Fang Zongwei Cai 
supported by the General Research Fund(grant no.12302122)of the Research Grants Council;Hong Kong Special Administrative Region,China,the Start-up Grant from Hong Kong Baptist University,and the State Key Laboratory of Environmental and Biological Analysis Research Grant(grant no.SKLP_2021_P04)。
A novel method for enhanced resolution,termed expansion mass spectrometry imaging,has been developed for lipid mass spectrometry imaging,utilizing existing commercially available mass spectrometers without necessitati...
关键词：mass spectrometry imaging MALDI imaging spatial lipidomics subcellular imaging EXPANSION molecular imaging high resolution 
Discovery of plasma biomarkers for Parkinson's disease diagnoses based on metabolomics and lipidomics
《Chinese Chemical Letters》2024年第11期260-265,共6页Xiaoxiao Wang Bolun Wang Fenfen Ji Jie Yan Jiacheng Fang Doudou Zhang Ji Xu Jing Ji Xinran Hao Hemi Luan Yanjun Hong Shulan Qiu Min Li Zhu Yang Wenlan Liu Xiaodong Cai Zongwei Cai 
support from the Collaborative Research Fund (No.C2011-21GF);Guangdong Province Basic and Applied Basic Research Foundation (No.2021B1515120051)。
Parkinson's disease(PD) is an aging-associated neurodegenerative movement disorder with increasing morbidity and mortality rates.The current gold standard for diagnosing PD is clinical evaluation,which is often challe...
关键词：Parkinson's disease Metabolomics LIPIDOMICS Machine learning BIOMARKER 
Exploring age and gender disparities in cardiometabolic phenotypes and lipidomic signatures among Chinese adults: a nationwide cohort study
《Life Metabolism》2024年第5期61-74,共14页Xiaojing Jia Hong Lin Ruizhi Zheng Shuangyuan Wang Yilan Ding Chunyan Hu Mian Li Yu Xu Min Xu Guixia Wang Lulu Chen Tianshu Zeng Ruying Hu Zhen Ye Lixin Shi Qing Su Yuhong Chen Xuefeng Yu Li Yan Tiange Wang Zhiyun Zhao Guijun Qin Qin Wan Gang Chen Meng Dai Di Zhang Bihan Qiu Xiaoyan Zhu Jie Zheng Xulei Tang Zhengnan Gao Feixia Shen Xuejiang Gu Zuojie Luo Yingfen Qin Li Chen Xinguo Hou Yanan Huo Qiang Li Yinfei Zhang Chao Liu Youmin Wang Shengli Wu Tao Yang Huacong Deng Jiajun Zhao Yiming Mu Shenghan Lai Donghui Li Weiguo Hu Guang Ning Weiqing Wang Yufang Bi Jieli Lu for theC Study Group 
supported by the National Natural Science Foundation of China(82170819,82370810,91857205,82088102,and 82200998);the National Key Research and Development Program of China(2022YFC2505202 and 2021YFA1301103);the Science and Technology Commission of Shanghai Municipality(23JS1400900,23Y11908400,and 23XD1422400);the Innovative research team of high-level local universities in Shanghai.
Understanding sex disparities in modifiable risk factors across the lifespan is essential for crafting individualized intervention strategies.We aim to investigate age-related sex disparity in cardiometabolic phenotyp...
关键词：sex difference AGING metabolic diseases modifiable risk factors LIPIDOMICS 
Herb Pair of Glycyrrhiza Radix–Platycodonis Radix Alleviates Respiratory Syncytial Virus Pneumonia in Mice by Modulating Lipid Metabolism and Inhibiting Inflammation
《World Journal of Traditional Chinese Medicine》2024年第3期322-333,共12页Yu Tang Chen Shi Ling Sun Bin Yang Jian-Jian Ji Tong Xie Shou-Chuan Wang Li-Li Lin Jin-Jun Shan 
the support of the National Natural Science Foundation of China (grant numbers 82174098,81774156);Jiangsu Provincial Six Talent Peaks Project (grant number YY-022);Jiangsu Qing Lan Project;Natural Science Foundation of Jiangsu Provincial Department of Education (20KJB320018)
Objective: The objective of this study is to explore the optimal ratio of Glycyrrhiza Radix(GR, Glycyrrhizae radix et Rhizoma) and Platycodonis Radix(PR, Platycodon grandifiorum A. DC) and its potential mechanism for ...
关键词：Apoptosis Glycyrrhiza Radix-Platycodonis Radix LIPIDOMICS respiratory syncytial virus pneumonia TLR3-NF-κB-NLRP3.signaling pathway 
High throughput screening of mesenchymal stromal cell morphological response to inflammatory signals for bioreactor-based manufacturing of extracellular vesicles that modulate microglia
《Bioactive Materials》2024年第7期153-171,共19页Andrew M.Larey Thomas M.Spoerer Kanupriya R.Daga Maria G.Morfin Hannah M.Hynds Jana Carpenter Kelly M.Hines Ross A.Marklein 
supported by the National Science Foundation under BIO-2036968,cooperative agreement EEC-1648035 (RAM),and UGA Research Foundation startup funds (KMH);supported in part by the Glycosciences Training Grant Program (NIH T32 GM145467)。
Due to their immunomodulatory function,mesenchymal stromal cells(MSCs)are a promising therapeutic with the potential to treat neuroinflammation associated with neurodegenerative diseases.This function is mediated by s...
关键词：Mesenchymal stromal cell High throughput screening Extracellular vesicle BIOREACTOR MICROGLIA LIPIDOMICS 
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