TERPENOID

作品数：58被引量：166H指数：6
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相关领域：生物学医药卫生更多>>
相关作者：王宗德姜志宽陈金珠金幼菊郝建华更多>>
相关机构：中国人民解放军南京军区军事医学研究所江西农业大学北京林业大学北京协和医学院药物研究所更多>>
相关期刊：《Journal of Integrative Plant Biology》《Journal of Integrative Medicine》《Asian Pacific Journal of Tropical Medicine》《Food Bioscience》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划国家教育部博士点基金国家科技支撑计划更多>>
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Unveiling the Mechanisms of Apoptosis Induction by Deep-Sea-Derived Polyketide-Terpenoid Hybrids from Penicillium allii-sativi:A Focus on Mitochondrial and mTOR Pathways
《Chinese Journal of Chemistry》2024年第24期3283-3292,共10页Chun-Lan Xie Tai-Zong Wu Duo Zhang Yuan Wang Ting Lin Hai-Feng Chen Xiao-Kun Zhang Xian-Wen Yang 
supported by the National Key Research and Development Program of China(2022YFC2084103);Xiamen Southern Oceanographic Center(22GYY007HJ07);the National Natural Science Foundation of China(22177143).
A chemical investigation of the deep-sea-derived fungus Penicillium allii-sativi MCCC 3A00580 resulted in the discovery of four new meroterpenoids(1—4)and one related known co-metabolite(5).These meroterpenoids showc...
关键词：Deep-sea-derived fungus Penicillium allii-sativi MEROTERPENOIDS Drimane sesquiterpene Peroxide Mitochondrial apoptosis mTOR Cancer treatment TERPENOID Structure elucidation 
Limonene’s Bacteriostatic Activity against Ralstonia solanacearum by Compromised Membrane Integrity: A Transcriptomic and Metabolomic Analysis
《Journal of Agricultural Chemistry and Environment》2024年第3期312-324,共13页Ruya Zhang Honghao Zhang Linfeng Li Yuchen Feng Lin Yang Jiaxin Liu Senfeng Gao Zihao Zhou Yong Yang Haibo Xiang Mei Li Jun Yu 
Ralstonia solanacearum, the causative agent of bacterial wilt, is a soil-borne pathogen that poses a widespread threat to plants in the Solanaceae family. To elucidate the mechanism by which limonene exerts its effect...
关键词：LIMONENE Transcriptome METABOLOME Ralstonia solanacearum Terpenoid Backbone Biosynthesis 
The effect of celastrol in combination with 5-fluorouracil on proliferation and apoptosis of gastric cancer cell lines
《Oncology Research》2024年第7期1231-1237,共7页MOHAMMAD-TAGHI MORADI DHIYA ALTEMEMY MAJID ASADI-SAMANI PEGAH KHOSRAVIAN MARZIYEH SOLTANI LEILA HASHEMI AZADEH SAMIEI-SEFAT 
supported by Shahrekord University of Medical Sciences,Shahrekord,Iran(Ethics Code:IR.SKUMS.REC.1397.119,Grant No.3696 and Ethics Code:IR.SKUMS.REC.1401.197,Grant No.6651).
Background:Despite the availability of chemotherapy drugs such as 5-fluorouracil(5-FU),the treatment of some cancers such as gastric cancer remains challenging due to drug resistance and side effects.This study aimed t...
关键词：Gastric cancer CELASTROL TERPENOID Cell cycle regulation APOPTOSIS Synergism 
Comparison of the effects and mechanisms of Alismatis Rhizoma with and without salt processing in ameliorating edema due to kidney Yin deficiency based on UPLC-Q-TOF-MS and transcriptomics被引量：1
《Science of Traditional Chinese Medicine》2024年第2期169-179,共11页Lin Yan Zemin Ou Yi Cheng Yan Tong Javed Iqbal Jinyu Wang Dewen Liu 
funded by the National Natural Science Foundation of China(Grant No.82003951).
Salt-processed Alismatis Rhizoma(SAR)is extensively used in clinical practice and exhibits a more robust urination-promoting effect than Alismatis Rhizoma(AR).This study employed ultra-performance liquid chromatograph...
关键词：Alismatis Rhizoma(AR) Salt-processed Alismatis Rhizome(SAR) Ultra-high performance liquid chromatographyquadrupole-time-of-flight mass spectrometry(UPLC-Q-TOF-MS) TERPENOID TRANSCRIPTOMICS 
Design,synthesis,and insecticidal activity of novel terpenoid ester compounds containing bicyclo[2.2.1]heptane against Aphis gossypii Glover被引量：1
《Advanced Agrochem》2024年第2期171-181,共11页Caiyue Liu Yuelan Yin Hao Liu Longfei Yang Minghui Chen Ting Ma Guoqiang Zhang Chunjuan Wang Sifeng Zhao Xiaoqiang Han 
supported by the National Natural Science Foundation of China(32260684);the Key Core Agricultural Technology Research Project of XPCC(NYHXGG2023AA602).
To discover novel and efficient compounds against Aphis gossypii Glover,a series of novel terpene ester derivatives containing the structure of bicyclo[2.2.1]heptane were designed and synthesized using tschimganin as t...
关键词：Aphis gossypii Terpene ester Insecticidal activity 3D-QSAR Metabolomics 
Chromosome-level assembly of triploid genome of Sichuan pepper(Zanthoxylum armatum)
《Horticultural Plant Journal》2024年第2期437-449,共13页Lizhi Song Yue Huang Hao Zuo Ning Tang Zhengguo Li Wenbiao Jiao Feng Xu Qiang Xu Zexiong Chen 
supported by the Projects for Innovative Research Groups of Chongqing Universities (Grant No.CXQT21028);Chongqing talent program for Zexiong Chen;Scientific Technological Research Program of Chongqing Municipal Education Commission (Grant No.KJZD-K201901303);National Natural Science Foundation of China (Grant No.31925034);National Key Research and Development Project (Grant No.2019YFD1001200)。
As an important spice species in Rutaceae, the Sichuan pepper (Zanthoxylum armatum) can provide pungent and numbing taste, as well as aroma in its mature fruit. Here we assembled a chromosome-level genome of green pri...
关键词：Zanthoxylum armatum Genome Sanshool TERPENOID 
Recent Advances in Microbial Production of Terpenoids from Biomass-derived Feedstocks
《Chemical Research in Chinese Universities》2024年第1期20-28,共9页CAO Yujin XIAN Mo 
the National Key Research and Development Program of China(No.2022YFC2104700).
Terpenoids are a diverse class of natural products widely used as pharmaceuticals,perfumes,flavors,and biofuels.Traditionally,terpenoids are obtained from natural sources,such as plants,but their production is limited...
关键词：TERPENOID Microbial production Biomass-derived feedstock Metabolic pathway 
Genome assembly of Polygala tenuifolia provides insights into its karyotype evolution and triterpenoid saponin biosynthesis被引量：1
《Horticulture Research》2023年第9期1-12,共12页Fanbo Meng Tianzhe Chu Pengmian Feng Nan Li Chi Song Chunjin Li Liang Leng Xiaoming Song Wei Chen 
supported by the Natural Science Foundation of Sichuan(No.2023NSFSC0683);Innovation Team and Talents Cultivation Program of the National Administration of Traditional Chinese Medicine(No:ZYYCXTD-D-202209);the‘Xinglin Scholar’Discipline Talent Research Promotion Program of Chengdu University of TCM(No.MPRC2021036).
Polygala tenuifolia is a perennial medicinal plant that has been widely used in traditional Chinese medicine for treating mental diseases.However,the lack of genomic resources limits the insight into its evolutionary ...
关键词：INSIGHT synthesis evolution 
Alternative Construction of the Core of Lindenane Sesquiterpenoid
《Chinese Journal of Chemistry》2023年第16期1931-1936,共6页Cichang Ling Zhengsong Huang Yuqiao Zhou Shaomin Fu Bo Liu 
NSFC(21925106,21901170);Sichuan University(2020SCUNL204).
Comprehensive Summary Alternative synthetic routes toward the tricyclic core of lindenane sesquiterpenoid are presented herein.The route A features an asymmetric organocatalysis enabling desymmetric silylation of diol...
关键词：TERPENOID Lindenane Total synthesis DESYMMETRIZATION EPOXIDATION Nucleophilic substitution CYCLOADDITION CYCLOPROPANATION 
A chromosome-scale genome assembly of Artemisia argyi reveals unbiased subgenome evolution and key contributions of gene duplication to volatile terpenoid diversity被引量：5
《Plant Communications》2023年第3期228-243,共16页Hongyu Chen Miaoxian Guo Shuting Dong Xinling Wu Guobin Zhang Liu He Yuannian Jiao Shilin Chen Li Li Hongmei Luo 
supported by the National Natural Science Foundation of China(81973422 and 31570302);the Chinese Academy of Medical Sciences(CAMS)Innovation Fund for Medical Sciences(2021-I2M-1-071).
Artemisia argyi Le´vl.et Vant.,a perennial Artemisia herb with an intense fragrance,is widely used in traditional medicine in China and many other Asian countries.Here,we present a chromosome-scale genome assembly of...
关键词：Artemisia argyi subgenome evolution gene duplication terpene synthase germacrene synthase nonartemisinin production 
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