GLUTAMINE

作品数：192被引量：905H指数：15
导出分析报告
相关领域：医药卫生更多>>
相关作者：林清华张楚富李常健彭进胡义德更多>>
相关机构：东南大学华中农业大学中国医学科学院基础医学研究所北京大学更多>>
相关期刊：更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划北京市自然科学基金国家教育部博士点基金更多>>
-
在结果中检索

检索结果分析

结果分析中...
共 条 记 录，以下是1-10
全选清除导出
参考文献引证文献引用追踪
视图：
排序：
D‑mannose alleviates intervertebral disc degeneration through glutamine metabolism
《Military Medical Research》2025年第3期313-338,共26页Zheng-Lin Dong Xin Jiao Zeng-Guang Wang Kai Yuan Yi-Qi Yang Yao Wang Yun-Tao Li Tian-Chang Wang Tian-You Kan Jian Wang Hai-Rong Tao 
supported by the National Key Research and Development Program of China(2020YFB1711505).
Background:Intervertebral disc degeneration(IVDD)is a multifaceted condition characterized by heterogeneity,wherein the balance between catabolism and anabolism in the extracellular matrix of nucleus pulposus(NP)cells...
关键词：D-MANNOSE Intervertebral disc degeneration(IVDD) Thioredoxin-interacting protein(TXNIP) GLUTAMINE 
Metabolic landscape of human alveolar type II epithelial cells undergoing epithelial-mesenchymal transition induced directly by silica exposure
《Journal of Environmental Sciences》2025年第3期676-687,共12页Jin Sun Na Zhao Ruijia Zhang Yizheng Li Tiantian Yu Qiying Nong Li Lin Xubin Yang Tiangang Luan Baowei Chen Yongshun Huang 
supported by the National Natural Science Foundation of China(Nos.22206207,22127810,and 22276224);the Natural Science Foundation of Guangdong Province(Nos.2021A1515011546 and 2023A1515010085);the Science and Technology Planning Project of Guangzhou(No.202102080005)。
Epithelial-mesenchymal transition(EMT)plays an irreplaceable role in the development of silicosis.However,molecular mechanisms of EMT induced by silica exposure still remain to be addressed.Herein,metabolic profiles o...
关键词：Silica exposure Human alveolar type II epithelial cells(ATII cells) Epithelial-mesenchymal transition(EMT) Metabolomics GLUTAMINE 
l-[5-^(11)C]Glutamine PET imaging noninvasively tracks dynamic responses of glutaminolysis in non-alcoholic steatohepatitis Author links open overlay panel
《Acta Pharmaceutica Sinica B》2025年第2期681-691,共11页Yiding Zhang Lin Xie Masayuki Fujinaga Yusuke Kurihara Masanao Ogawa Katsushi Kumata Wakana Mori Tomomi Kokufuta Nobuki Nengaki Hidekatsu Wakizaka Rui Luo Feng Wang Kuan Hu Ming-Rong Zhang 
supported in part by the Moonshot Research and Development Program(Grant No.21zf0127003h001,Japan);JSPS A3 Foresight Program(Grant No.JPJSA3F20230001,Japan);JSPS KAKENHI(Grants No.23H02867,23H05487,and 21K07659,Japan).
Inhibiting glutamine metabolism has been proposed as a potential treatment strategy for improving non-alcoholic steatohepatitis(NASH).However,effective methods for assessing dynamic metabolic responses during interven...
关键词：l-[5-^(11)C]Glutamine Positron emission tomography Non-alcoholic steatohepatitis GLUTAMINOLYSIS Glutaminase 1 Metabolic intervention BPTES therapy 
Modulation of tRNA^(Cln)decoding efficacy by metal ion binding and glutamine supply
《Journal of Chinese Pharmaceutical Sciences》2025年第1期28-40,共13页Yuxuan Shen Tianchang Wang Hua Qiao Qing Liang Jingru Lv Qing Xia 
National Natural Science Foundation of China(Grant No.U23A20106);National Key Research and Development Program of China(Grant No.91510100MA6CG8UJ4K)。
Transfer RNAs(tRNAs)adopt a stable L-shaped tertiary structure crucial for their involvement in protein translation.Among various divalent metal ions,magnesium ions play a pivotal role in preserving the tertiary struc...
关键词：Metal ions tRNA tertiary structure Glutamine supply Decoding efficacy 
CRL3 E3 ligase regulates glutamine and cystine metabolisms
《Protein & Cell》2024年第12期867-871,共5页Qiyin Zhou Zhijian Li Yi Sun 
supported by the National Key Research&Development Program of China(2021YFA1101000 and 2022YFC3401500);National Natural Science Foundation of China(82372688,92253203 and U22A20317);Leading Innovative and Entrepreneur Team Introduction Program of Zhejiang(2022R01002);Zhejiang Provincial Natural Science Foundation of China(LD22H300003)。
Tumorigenesis hinges on the reprogramming of cellular metabolisms to meet the requirements of intracellular biomass,characterized by the acquisition of nutrients from the environment as a common feature(Pavlova and Th...
关键词：METABOLISM PROGRAMMING utilized 
Enteral glutamine supplements for patients with severe burns:A systematic review and meta-analysis被引量：1
《Chinese Journal of Traumatology》2024年第6期359-367,共9页Han-Yang Yue Yu Wang Jun Zeng Hua Jiang Wei Li 
supported by the Sichuan Science and Technology Support Program(Grant ID:2021YFS0378 to Hua Jiang,23ZDYF1907 to Wei Li);the National Natural Science Foundation of China(Grant ID:71974200 to Hua Jiang)。
Purpose:Our previous study in 2009 concluded that glutamine may shorten the length of hospital stay(LOS)in patients with severe burns.Recent large-scale studies have suggested a decline in the effectiveness of glutami...
关键词：GLUTAMINE Enteral nutrition Critical care BURN MORTALITY Systematic review 
C-myc modulates the replication of RGNNV via glutamine-mediated ATP production in grouper fin cells
《Aquaculture and Fisheries》2024年第6期929-936,共8页Minshan Yao Hong Chen Junjie Tao Lixiang Wei Ying Tang Junyan Lin Fei Shi Fanbin Zhan Yanan Li Jun Li Zhendong Qin Li Lin 
jointly supported by the National Natural Science Foundation of China(31872606,31902409,31572657,U1701233).
C-myc is a proto-oncogene that plays an important role in a variety of diseases.There were a lot of research on the correlation between C-myc and human viruses.However,the study about C-myc related to aquatic species ...
关键词：Red grouper nervous necrosis virus(RGNNV) C-MYC GLUTAMINE ATP 
Glutamine and Its Actions: A Bird’s Eye View
《Journal of Biosciences and Medicines》2024年第11期484-508,共25页Aketzali Y. Fernández-Delgado Santiago C. Sigrist-Flores Jessica E. Rodríguez-Rodríguez Itzell A. Gallardo-Ortíz Rafael Villalobos-Molina 
Glutamine (Gln) is the most abundant amino acid in the body, playing a versatile role in both maintaining homeostasis and contributing to various pathologies. This review explores the physiological functions of Gln, d...
关键词：GLUTAMINE METABOLISM Immune System Cancer Hepatic Encephalopathy BURNS 
Single-cell analysis revealing the metabolic landscape of prostate cancer
《Asian Journal of Andrology》2024年第5期451-463,共13页Jing Wang He-Kang Ding Han-Jiang Xu De-Kai Hu William Hankey Li Chen Jun Xiao Chao-Zhao Liang Bing Zhao Ling-Fan Xu 
supported by the National Natural Science Foundation of China(No.81902611,82272886,and 82200484);USTC Research Funds of the Double First-Class Initiative(YD9110002041);the Natural Science Foundation of Anhui Education Department(No.2022AH030118).
Tumor metabolic reprogramming is a hallmark of cancer development,and targeting metabolic vulnerabilities has been proven to be an effective approach for castration-resistant prostate cancer(CRPC)treatment.Nevertheles...
关键词：cancer heterogeneity cancer metabolism GLUTAMINE prostate cancer single-cell sequencing 
AMPK targets PDZD8 to trigger carbon source shift from glucose to glutamine被引量：1
《Cell Research》2024年第10期683-706,共24页Mengqi Li Yu Wang Xiaoyan Wei Wei-Feng Cai Jianfeng Wu Mingxia Zhu Yongliang Wang Yan-Hui Liu Jinye Xiong Qi Qu Yan Chen Xiao Tian Luming Yao Renxiang Xie Xiaomin Li Siwei Chen Xi Huang Cixiong Zhang Changchuan Xie Yaying Wu Zheni Xu Baoding Zhang Bin Jiang Zhi-Chao Wang Qinxi Li Gang Li Shu-Yong Lin Li Yu Hai-Long Piao Xianming Deng Jiahuai Han Chen-song Zhang Sheng-Cai Lin 
supported by grants from the National Key R&D Program of China(2020YFA0803402);the National Natural Science Foundation of China(#92057204,#82088102,#32070753,#31900542,#91854208,#31922034,and#323B2035);the Fundamental Research Funds for the Central Universities(#20720200069);the Project"111"sponsored by the State Bureau of Foreign Experts and Ministry of Education of China(#BP2018017);the Joint Funds for the Innovation of Science and Technology,Fujan province(2021Y9232,2021Y9227,2023Y9448);the Fujian provincial health technology project(2022ZD01005,2022ZQNZD009);the Special Research Funds for Local Science and Technology Development Guided by Central Government(2023L3020);the XMU Fujian Cancer Hospital cooperation grant for the Research Center of Metabolism and Tumor,the XMU Training Program of Innovation and Entrepreneurship for Undergraduates(2021x1183 and 2022Y1233);the Agilent Applications and Core Technology-University Research Grant(#4769).
The shift of carbon utilization from primarily glucose to other nutrients is a fundamental metabolic adaptation to cope with decreased blood glucose levels and the consequent decline in glucose oxidation.AMP-activated...
关键词：AMPK PDZ TOGETHER 
全选清除导出
共20页<12345678910>
检索报告 对象比较 聚类工具 使用帮助 返回顶部