ATROPHY

作品数：252被引量：535H指数：12
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相关作者：李亮廉哲雄姚远陈晓林吕文更多>>
相关机构：中国科学技术大学首都医科大学广州医学院第三附属医院浙江大学医学院附属第一医院更多>>
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Gene therapy for spinal muscular atrophy:perspectives on the possibility of optimizing SMN1 delivery to correct all neurological and systemic perturbations
《Neural Regeneration Research》2025年第7期2011-2012,共2页Sharon J.Brown Rafael J.Yáñez-Muñoz Heidi R.Fuller 
supported by the Faculty Research Fund(Faculty of Medicine&Health Science,Keele University)Career Development Award–(April 2022)(to SJB)。
Spinal muscular atrophy(SMA)is a genetic condition that results in selective lower motor neuron loss with concomitant muscle weakness and atrophy.The genetic cause of SMA was understood in 1995 when loss or impairment...
关键词：ATROPHY traditionally absolute 
Meibomian gland atrophy in children with allergic conjunctivitis
《International Journal of Ophthalmology(English edition)》2025年第5期832-839,共8页Wen-Fang He Yi-Ping Wu Jing-Wei Zheng Bin-Ge Huang Jing-Jing Zuo Jin-Yang Li Dan Jiang Hui-Xiang Ma 
Supported by the Natural Science Foundation of the Zhejiang Province(No.LGD22H120002).
AIM:To investigate the factors influencing meibomian gland atrophy(MGA)in children with allergic conjunctivitis(AC).METHODS:In this cross-sectional study,60 children with AC aged 6-17y and 20 age-matched children with...
关键词：allergic conjunctivitis meibomian gland atrophy CHILDREN 
OCT predictors of retinal atrophy in neovascular agerelated macular degeneration treated with aflibercept
《International Journal of Ophthalmology(English edition)》2025年第4期648-655,共8页Oscar MGagliardi Ludovico Alisi Giacomo Visioli Federica Dini Giuseppe MAlbanese Stefano Scordari Marco Marenco Alessandro Lambiase Rosalia Giustolisi 
AIM:To identify optical coherence tomography(OCT)features present at the diagnosis of neovascular age-related macular degeneration(nAMD)that could predict retinal atrophy(RA)and visual performance in patients treated ...
关键词：neovascular age-related macular degeneration long-term prognosis optical coherence tomography OCT predictors retinal atrophy 
Refractory lipoatrophy treated with autologous whole blood injection:A case report
《World Journal of Clinical Cases》2025年第2期33-38,共6页Wonnam Kim Jun Su Park En Hyung Kim 
Supported by The New Faculty Research Grant of Pusan National University,2023;The Research Grant of the Chungbuk National University in 2023.
BACKGROUND Intramuscular corticosteroid injection may cause adverse effects such as dermal and/or subcutaneous atrophy,alopecia,hypopigmentation,and hyperpigmentation.Although cutaneous atrophy can spontaneously resol...
关键词：ATROPHY CORTICOSTEROID Subcutaneous fat Autologous whole blood injection Laser therapy Case report 
Strain-dependent alpha-synuclein spreading in Parkinson's disease and multiple system atrophy被引量：1
《Neural Regeneration Research》2024年第12期2581-2582,共2页Shuyu Zhang Paul Lingor 
supported by Deutsche Forschungsgemeinschaft;EXC 2145 SyNergy;Grant No.390857198 (to PL)。
Parkinson's disease(PD) and atypical Parkinsonian syndromes,such as multiple system atrophy(MSA) and Dementia with Lewy bodies,are neurodegenerative movement disorders characterized by the accumulation of alphasynucle...
关键词：ATROPHY ENDOGENOUS ATYPICAL 
Seasonal remodeling of visceral organs in the invasive desert gecko Tarentola annularis
《Integrative Zoology》2024年第6期1047-1056,共10页Shahar DUBINER Shai MEIRI Eran LEVIN 
Shahar Dubiner was supported by the Azrieli Graduate Studies Fellowship.
In winter,many reptiles have a period of inactivity(“brumation”).During brumation there is no energetic intake,therefore there would be an advantage to reducing energetic expenditure.The size of energetically costly...
关键词：ATROPHY brumation HIBERNATION metabolic rate organ size REPTILE winter 
A study of the correlation between gray matter atrophy in multiple sclerosis and impairment of cognitive function domains
《China Medical Abstracts(Internal Medicine)》2024年第3期189-190,共2页HAN Jing 
Objective To quantify cerebral cortical and deep gray matter atrophy in patients with multiple sclerosis(MS) and explore its correlation with impairment in domains of cognitive function.Methods Twenty patients with MS...
关键词：IMPAIRMENT ATROPHY function. 
TL1A and IL-18 synergy promotes GM-CSF-dependent thymic granulopoiesis in mice被引量：1
《Cellular & Molecular Immunology》2024年第8期807-825,共19页Mario Ruiz Pérez Christian Maueröder Wolf Steels Bruno Verstraeten Sahine Lameire Wei Xie Laura Wyckaert Jelle Huysentruyt Tatyana Divert Ria Roelandt Amanda Gonçalves Riet De Rycke Kodi Ravichandran Bart N.Lambrecht Tom Taghon Georges Leclercq Peter Vandenabeele Peter Tougaard 
FWO Research Grants G.0B96.20N(PV,PT),G.0C76.18N(PV),G.0B71.18N(PV);G.0A93.22N(PV);Special Research Fund UGent(Methusalem grant BOF16/MET_V/007(PV);BOF22/MET_V/007(PV);iBOF ATLANTIS grant 20/IBF/039(PV));EOS MODEL-IDI Grant(30826052)(PV);EOS CD-INFLADIS(40007512)(PV);Foundation against Cancer(F/2016/865,F/2020/1505)(PV).FWO fundamental research fellowship PhD grant(MRP)(11A7222N);FWO senior postdoctoral fellowship(CM)(12Y2122N);DFG research fellowship(CM)(MA 7770/1-1);Cancer Research Institute Ghent(CRIG)consortia;Ghent Gut Inflammation Group(GGIG)consortia.Flanders Institute for Biotechnology(VIB).
Acute systemic inflammation critically alters the function of the immune system,often promoting myelopoiesis at the expense of lymphopoiesis.In the thymus,systemic inflammation results in acute thymic atrophy and,cons...
关键词：Thymic Neutrophils Emergency granulopoiesis Thymus atrophy Thymic GMP Cytokine synergy 
Diabetes mellitus in patients with type 1 autoimmune pancreatitis at diagnosis and after corticosteroid therapy被引量：2
《Hepatobiliary & Pancreatic Diseases International》2024年第4期393-398,共6页Mei-Zi Li Tao Guo Yun-Lu Feng Sheng-Yu Zhang Xiao-Yin Bai Xi Wu Kai Xu Ai-Ming Yang 
from CAMS Innovation Fund for Medical Sciences(CIFMS)(2021-I2M-1-002);National Key Clinical Specialty Construction Project(ZK108000);National High-Level Hospital Clinical Research Funding(2022-PUMCH-B-024);National Natural Science Foundation of China,Joint Fund Project(U20A600).
Background:A high prevalence of diabetes mellitus(DM)coexisting with autoimmune pancreatitis(AIP)is observed.However,evidence on the circumstances under which corticosteroid therapy(CST)for AIP improves or worsens DM ...
关键词：Type 1 autoimmune pancreatitis Diabetes mellitus Corticosteroid therapy Predictive factor Pancreatic atrophy 
Construction of a cell-based aggregation and seeding model for the Tau protein
《Acta Biochimica et Biophysica Sinica》2024年第7期1085-1088,共4页Jiying Hu Liqiang Wang Jie Chen Yi Liang 
supported by the grants from the National Natural Science Foundation of China(Nos.32271326,32071212,and 31770833 to Y.L.and No.32201040 to L.W.);the Key Project of Basic Research,Science and Technology R&D Fund of Shenzhen(No.JCYJ20200109144418639 to Y.L.).
A pathological hallmark of Alzheimer’s disease(AD),the most common neurodegenerative disease in elderly people,is the formation of neurofibrillary tangles(NFTs),which are mainly composed of bundles of amyloid fibrils...
关键词：ALZHEIMER ATROPHY PATHOLOGY 
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