Refractory lipoatrophy treated with autologous whole blood injection:A case report  

作　　者：Wonnam Kim Jun Su Park En Hyung Kim 

机构地区：[1]Department of Pharmacology,School of Korean Medicine,Pusan National University,Yangsan 50612,Gyeongnam,South Korea [2]Department of Dermatology,College of Medicine,Chungbuk National University,Cheongju 28644,Chungbuk,South Korea [3]Department of Dermatology,Chungbuk National University Hospital,Cheongju 28644,Chungbuk,South Korea

出　　处：《World Journal of Clinical Cases》2025年第2期33-38,共6页世界临床病例杂志（英文）

基　　金：Supported by The New Faculty Research Grant of Pusan National University,2023;The Research Grant of the Chungbuk National University in 2023.

摘　　要：BACKGROUND Intramuscular corticosteroid injection may cause adverse effects such as dermal and/or subcutaneous atrophy,alopecia,hypopigmentation,and hyperpigmentation.Although cutaneous atrophy can spontaneously resolve,several treatment options have been suggested for this condition.CASE SUMMARY In this paper,we report a case of corticosteroid injection induced lipoatrophy treated with autologous whole blood(AWB)injection,as the condition had been unresponsive to fractional laser therapy.A 29-year-old female patient visited the dermatology clinic complaining of skin depression on her right buttock area,which had appeared six months earlier.There had been only subtle improvement at the margins after fractional CO_(2) laser treatment;therefore,after obtaining informed consent from the patient,AWB treatment was initiated.One month after the first AWB injection,the size and depth of the lesion had noticeably improved,and a slight improvement was also observed in discoloration.CONCLUSION Close observation is the initial treatment of choice for steroid induced skin atrophy;however,for patients in need of immediate cosmetic improvement,AWB injection may be a safe and cost-effective alternative.

关 键 词：ATROPHY CORTICOSTEROID Subcutaneous fat Autologous whole blood injection Laser therapy Case report 

分 类 号：R75[医药卫生—皮肤病学与性病学]