Context-dependency in medicine:how neuronal excitability influences the impact of dopamine on cognition  

作　　者：Mahboubeh Ahmadi Nahid Rouhi Javad Mirnajafi-Zadeh Bechara J.Saab 

机构地区：[1]Department of Physiology,Faculty of Medical Sciences,Tarbiat Modares University,Tehran,Iran [2]Mobio Interactive Pte.Ltd.,Singapore,Republic of Singapore

出　　处：《Neural Regeneration Research》2025年第11期3225-3226,共2页中国神经再生研究（英文版）

摘　　要：Dopamine,often termed the"feel-good"neurotransmitter,plays a crucial role in myriad physiological and psychological brain processes.While dopamine is primarily associated with pleasure,reward,and motivation,its effects can be quite complex;and this complexity is further compounded when examining how dopamine functions in typical versus disease-affected neural circuits.In pa rticula r,epilepsy,characte rized by heightened brain excitability,is linked to cognitive dysfunction,and dopamine is implicated in elements of both its pathology and treatment.Neuroscience has been successful in describing the synaptic abnormalities believed to contribute to memory issues in epilepsy,aiding in the search for effective therapies for what persists as a major medical issue.

关 键 词：DOPAMINE EPILEPSY primarily 

分 类 号：R741.02[医药卫生—神经病学与精神病学]