How dopamine tunes parvalbumin interneurons in the hippocampus:new experimental observations in Alzheimer's disease  

作　　者：Livia La Barbera Paraskevi Krashia Annalisa Nobili 

机构地区：[1]Department of Medicine and Surgery,UniversitàCampus Bio-Medico di Roma,ViaÁlvaro del Portillo,Rome,Italy [2]Department of Experimental Neurosciences,IRCCS Santa Lucia Foundation,Via del Fosso di Fiorano,Rome,Italy [3]Department of Science and Technology for Sustainable Development and One Health,UniversitàCampus Bio-Medico di Roma,ViaÁlvaro del Portillo,Rome,Italy

出　　处：《Neural Regeneration Research》2025年第5期1405-1406,共2页中国神经再生研究（英文版）

基　　金：supported by an under-40 grant from the Italian Association for Alzheimer’s Research [AIRALZH AGYR2021];the Strategic University Projects–Young Researcher Independence grant [YRG2021] from the Università Campus Bio-Medico di Roma (Rome, Italy)(to LLB);Italian Ministry of Health [Research Grant:GR-2019-12370446];the American Alzheimer’s Association [AARG-22-922961](to PK)。

摘　　要：Despite decades of dedicated resea rch,Alzheimer's disease (AD) is an age-related and progressive neurodegenerative disorder for which the mechanisms of onset are sti unc ear.AD is cha racterized by featured histological alterations including amyloid-beta (AB) plaque deposition,accumulation of neurofibrillary to ngles of hyperphosphorylated-tau,and neuronal loss,accompanied by progressive cognitive decline and behavioral changes.

关 键 词：ALZHEIMER alterations DOPAMINE 

分 类 号：R749.16[医药卫生—神经病学与精神病学]