云南高校图书馆联盟文献共享服务平台- INTEGRIN

INTEGRIN: 作品数：325被引量：710H指数：12; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：刘持向阳秦晓群刘惠君朱晓琳更多>>; 相关机构：中南大学天津医科大学四川大学华中科技大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金中国博士后科学基金国家重点基础研究发展计划广东省自然科学基金更多>>

Dynamic development of microglia and macrophages after spinal cord injury: 《Neural Regeneration Research》2025年第12期3606-3619,共14页Hu-Yao Zhou Xia Wang Yi Li Duan Wang Xuan-Zi Zhou Nong Xiao Guo-Xing Li Gang Li; Secondary injury following spinal cord injury is primarily characterized by a complex inflammatory response,with resident microglia and infiltrating macrophages playing pivotal roles.While previous studies have groupe...; 关键词：acute inflammation bioinformatics analysis FIBROBLAST integrinβ2 ligand-receptor interaction NEUROINFLAMMATION oncostatin M single-cell RNA sequencing spatial transcriptomics spinal cord injury

Therapeutic potential of integrins in diabetic retinopathy: 《World Journal of Diabetes》2025年第5期109-118,共10页Li-Mei He Sarul Borjigin Xin-Qi Chen Zhao-Li Yan Ming-Jie Wang; Supported by the Natural Science Foundation of Inner Mongolia,No.2022MS08057;2022 Autonomous Region Medical and Health Science and Technology Plan Projects,No.202202190.; Diabetic retinopathy(DR),a leading cause of visual loss,is the result of microvascular damage induced by prolonged hyperglycemia.Numerous studies have revealed the pivotal role of integrins in the pathogenesis of DR,p...; 关键词：Diabetic retinopathy INTEGRIN INFLAMMATION Microvascular permeability Microthrombus formation ANGIOGENESIS Integrin inhibitor

SerpinA5调控Fn/Integrin-β1信号通路抑制食管鳞癌恶性生物学行为: 《肿瘤防治研究》2025年第4期290-296,共7页魏瑜张周华李志芳张莉; 新疆维吾尔自治区自然科学基金(2021D01C-352)。; 目的探讨SerpinA5对食管鳞癌(ESCC)细胞恶性生物学行为的影响及其分子机制。方法通过TIMER2.0数据库分析SerpinA5基因在不同肿瘤和相邻正常组织之间的表达水平。Western blot检测SerpinA5在ESCC细胞系和食管上皮细胞中的表达情况。利用...; 关键词：食管鳞状细胞癌 SerpinA5 恶性生物学行为 Fn/Integrin-β1信号通路

Salmonella Yrb D protein mediates invasion into the host by interacting withβ2 integrin: 《Journal of Integrative Agriculture》2025年第3期1181-1197,共17页Jun Cao Jinliang Wang Guanghui Dang Shihao Ding Yao Lu Qiu Xu Siguo Liu Shenye Yu; supported by the National Key R&D Program of China(2022YFF0710500);the the National Natural Science Foundation,China(31802192,32172853 and 32373013);the Natural Science Foundation of Heilongjiang Province of China(C2018070);China Postdoctoral Science Foundation(2017M620076);the Central Public-interest Scientific Institution Basal Research Fund,China(1610302022001)。; Salmonella enterica serovar Typhimurium,the causative agent of gastroenteritis,is one of the most successful intracellular pathogens.Although certain host factors for Salmonella infection have been unveiled,the factor...; 关键词：β2 integrin adhesion INTERNALIZATION SALMONELLA protein Yrb D

EMP2 promotes hepatocellular carcinoma proliferation and invasion by activating cellular autophagy: 《Oncology Research》2025年第2期443-464,共22页HAIYING PANG FENGBO WU YU ZHANG NAN ZHANG CHUNTING WANG QIU LI GU HE PENG ZHANG; supported by the Fundamental Research Funds for the National Natural Science Foundation of China(Nos.22177084 and 82104373);the Fundamental Research Funds of Science&Technology Department of Sichuan Province(No.2022YFQ0054).; Background:EMP2 is a tumor-associated membrane protein belonging to the GAS-3/PMP22 gene family.EMP2 expression demonstrates significant tissue specificity and heterogeneity in various human tissues and tumor tissues,...; 关键词：Epithelial membrane protein 2 Hepatocellular carcinoma AUTOPHAGY Integrin pathway

Corrigendum to:Downregulating integrin subunit alpha 7(ITGA7)promotes proliferation,invasion,and migration of papillary thyroid carcinoma cells through regulating epithelial-to-mesenchymal transition: 《Acta Biochimica et Biophysica Sinica》2025年第2期325-325,共1页Yaoyao Guan Adheesh Bhandari Erjie Xia Lingguo Kong Xiaohua Zhang Ouchen Wang; Acta Biochim Biophys Sin 2020,52(2):116–124 https://doi.org/10.1093/abbs/gmz144 In the original version of this manuscript,an error was found in Figure 4.The correct figure is as follows.The authors apologize for the...; 关键词：INVASION COR FIGURE

Safety,pharmacokinetics,and dosimetry of^(177)Lu-AB-3PRGD2 in patients with advanced integrinα_(v)β_(3)-positive tumors:A first-in-human study: 《Acta Pharmaceutica Sinica B》2025年第2期669-680,共12页Huimin Sui Feng Guo Hongfei Liu Rongxi Wang Linlin Li Jiarou Wang Chenhao Jia Jialin Xiang Yingkui Liang Xiaohong Chen Zhaohui Zhu Fan Wang; supported by Chinese Academy of Medical Science Innovation Fund for Medical Sciences(2022-I2M-2-002);the National High-Level Hospital Clinical Research Funding(2022-PUMCH-D-002,China);Clinical and translational medicine research project of the Chinese Academy of Medical Sciences(2022-I2M-C&T-A-008,China),the National Natural Science Foundation of China(82272046);the Fundamental Research Funds for the Central Universities(3332023124,China).; Integrinα_(v)β_(3)is overexpressed in various tumor cells and angiogenesis.To date,no drug has been proven to target it for therapy.A first-in-human study was designed to investigate the safety,pharmacokinetics,and ...; 关键词：^(177)Lu-AB-3PRGD2 Integrinα_(v)β_(3) Targeted radionuclide therapy First-in-human study PHARMACOKINETICS DOSIMETRY Safety Advanced tumors

Rab1 and Syntaxin 17 regulate hematopoietic homeostasis through β-integrin trafficking in Drosophila: 《Journal of Genetics and Genomics》2025年第1期51-65,共15页Fangzhou Luo Luwei Sui Ying Sun Zhixian Lai Chengcheng Zhang Gaoqun Zhang Bing Bi Shichao Yu Li Hua Jin; supported by the National Natural Science Foundation of China(32170484 and 32300384);the Fundamental Research Funds for the Central Universities(2572022DQ07 and 2572020AW04).; Hematopoiesis is crucial for organismal health,and Drosophila serves as an effective genetic model due to conserved regulatory mechanisms with vertebrates.In larvae,hematopoiesis primarily occurs in the lymph gland,wh...; 关键词：HEMATOPOIESIS Lymphgland Rab1 Syntaxin 17 β-integrin DROSOPHILA

Bushen Huoxue decoction(补肾活血汤)improves the reproduction of endometriosis-associated infertility by regulating Homeobox A10 and αlpha(v)beta(3)integrin expression: 《Journal of Traditional Chinese Medicine》2024年第6期1137-1145,共9页TANG Weiwei LIU Kaili FAN Xumei ZHU Li ZENG Zheng SUN Jiali SHI Jie ZHANG Zhenzhen GUI Tao WAN Guiping; National Natural Science Foundation-funded Project:the Mechanism of Effect of Bushen Huoxue Decotion on Endometrial Receptivity in Endometriosis (No. 81603372);National Natural Science Foundation-funded Project:to Investigate the Mechanism of Bushen Huoxue Decoction in Improving Endometrial Receptivity Based on SUMOylation of Homeobox A10 (No. 82274190);Jiangsu Commission of Health Project:to Investigate the Mechanism of Bushen Huoxue Decoction in Improving Endometrial Receptivity Based on Leukemia Inhibitory Factor Signaling (No. M2022079)。; OBJECTIVE: To investigate the mechanism of Bushen Huoxue decoction( 补肾活血汤, BSHXD) to treat endometriosis-induced infertility. MEDHODS: The main compounds of BSHXD were determined by high performance liquid chroma...; 关键词：INFERTILITY ENDOMETRIOSIS homeobox A10 proteins integrin alpha Vbeta3 Bushen Huoxue decoction

Integrin β4 in Breast Cancer: A Focused Review: 《Journal of Biosciences and Medicines》2024年第11期255-272,共18页Zoya Salahuddin Shuhan Ying Emily Xie Aizhang Xu Xiaojing Ma; Integrin β4 (ITGB4) is emerging as a pivotal player in breast cancer progression, particularly in aggressive and invasive subtypes such as triple-negative breast cancer (TNBC). This review broadly summarizes current ...; 关键词：INTEGRINS ITGB4 Prognosis EMT ANGIOGENESIS Drug Resistance Cancer Therapy

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