INTEGRINS

作品数：57被引量：152H指数：7
导出分析报告
相关领域：医药卫生生物学更多>>
相关作者：沈阳刘肖珩王利娟余泓池邓力更多>>
相关机构：四川大学中国医科大学山东中医药大学四川大学华西医院更多>>
相关期刊：更多>>
相关基金：国家自然科学基金SA-SIBS优秀人才奖励基金国家教育部博士点基金国家基础科学人才培养基金更多>>
-
在结果中检索

检索结果分析

结果分析中...
共 条 记 录，以下是1-10
全选清除导出
参考文献引证文献引用追踪
视图：
排序：
Therapeutic potential of integrins in diabetic retinopathy
《World Journal of Diabetes》2025年第5期109-118,共10页Li-Mei He Sarul Borjigin Xin-Qi Chen Zhao-Li Yan Ming-Jie Wang 
Supported by the Natural Science Foundation of Inner Mongolia,No.2022MS08057;2022 Autonomous Region Medical and Health Science and Technology Plan Projects,No.202202190.
Diabetic retinopathy(DR),a leading cause of visual loss,is the result of microvascular damage induced by prolonged hyperglycemia.Numerous studies have revealed the pivotal role of integrins in the pathogenesis of DR,p...
关键词：Diabetic retinopathy INTEGRIN INFLAMMATION Microvascular permeability Microthrombus formation ANGIOGENESIS Integrin inhibitor 
Impacts of PI3K/protein kinase B pathway activation in reactive astrocytes: from detrimental effects to protective functions
《Neural Regeneration Research》2025年第4期1031-1041,共11页Ramón Pérez-Núñez María Fernanda González Ana María Avalos Lisette Leyton 
supported by Fondo Nacional de Desarrollo Científico y Tecnológico(FONDECYT)#1200836,#1210644,and#1240888,and Agencia Nacional de Investigación y Desarrollo(ANID)-FONDAP#15130011(to LL);FONDECYT#3230227(to MFG).
Astrocytes are the most abundant type of glial cell in the central nervous system.Upon injury and inflammation,astrocytes become reactive and undergo morphological and functional changes.Depending on their phenotypic ...
关键词：inflammation INTEGRINS NEUROPROTECTIVE NEUROTOXIC phosphatidylinositol 3-kinase reactive astrocytes signal transduction Thy-1(CD90) 
Biological processes involved in mechanical force transmission in connective tissue:Linking bridges for new therapeutic applications in the rehabilitative field
《BIOCELL》2025年第1期1-5,共5页AUGUSTO FUSCO STEFANO BONOMI LUCA PADUA 
Connective tissue is a dynamic structure that reacts to environmental cues to maintain homeostasis,including mechanical properties.Mechanical load influences extracellular matrix(ECM)—cell interactions and modulates ...
关键词：Connective tissue Cellular mechanotransduction INTEGRINS Translational science 
Integrin β4 in Breast Cancer: A Focused Review
《Journal of Biosciences and Medicines》2024年第11期255-272,共18页Zoya Salahuddin Shuhan Ying Emily Xie Aizhang Xu Xiaojing Ma 
Integrin β4 (ITGB4) is emerging as a pivotal player in breast cancer progression, particularly in aggressive and invasive subtypes such as triple-negative breast cancer (TNBC). This review broadly summarizes current ...
关键词：INTEGRINS ITGB4 Prognosis EMT ANGIOGENESIS Drug Resistance Cancer Therapy 
Integrins and NAFLD-associated liver diseases:clinical associations,pathophysiological mechanisms and pharmacological implications
《Acta Biochimica et Biophysica Sinica》2024年第11期1573-1583,共11页Yangyue Ni Mengwen Huang Shiyang Chen Shihui Wang Jianfeng Chen 
This work was supported by the grants from the National Key R&D Program of China(Nos.2020YFA0509003 and 2020YFA0509102 to J.C.);the National Natural Science Foundation of China(Nos.31830112,32030024,31900536,32170769 to J.C.,No.32300633 to M.H.,and No.32200642 to S.C.);the Program of Shanghai Academic Research Leader(No.19XD1404200 to J.C.);the China Postdoctoral Science Foundation(No.2023M733487 to M.H.and No.2020M671262 to S.W.);the China Postdoctoral Innovative Talent Support Program(No.BX20190345 to S.W.)。
Nonalcoholic fatty liver disease(NAFLD)is a leading cause of chronic liver disease and poses a substantial health burden with increasing incidence globally.NAFLD encompasses a spectrum extending from hepatic steatosis...
关键词：INTEGRINS NAFLD NASH NAFLD-related HCC diagnostics and treatments 
A commentary on the interplay of biomaterials and cell adhesion:new insights in bone tissue regeneration
《BIOCELL》2024年第11期1517-1520,共4页A.NOEL GRAVINA NOELIA D´ELÍA LUCIANO A.BENEDINI PAULA MESSINA 
This article navigates the relationship between biomaterials and osteogenic cell adhesion,highlighting the importance of mimicking the physiological response for bone tissue regeneration.Within this spirit is an initi...
关键词：OSTEOGENESIS CADHERINS INTEGRINS Extracellular cell matrix 
Ⅴ型胶原蛋白通过Integrins调控急性缺血性心肌损伤的机制被引量：1
《中国老年学杂志》2024年第16期4026-4030,共5页贾慧宇 常永峰 韩培天 李术伟 
河北省医学科学研究课题(20200498);张家口市重点研发计划项目(2221194D)。
目的探究Ⅴ型胶原蛋白(Col5)α1通过整合素(Integrins)调控急性心肌缺血性损伤的分子机制。方法将SPF级C57/BL6小鼠分为对照组、模型组和Col5α1组,各10只。模型组和Col5α1组建立急性心肌缺血性损伤模型,Col5α1组建模后尾静脉注射Col5...
关键词：Ⅴ型胶原蛋白α1 急性心肌缺血性损伤 心肌细胞 细胞凋亡 鸟嘌呤核苷酸交换因子(GEF) 
Transforming growth factor-β receptors:versatile mechanisms of ligand activation被引量：1
《Acta Pharmacologica Sinica》2024年第7期1337-1348,共12页Zheng-Jie Chia Ying-nan Cao Peter J.Little Danielle Kamato 
supported by a Future Leader Fellowship (106605)from the National Heart Foundation of Australia.
Transforming growth factor-β(TGF-β)signaling is initiated by activation of transmembrane TGF-βreceptors(TGFBR),which deploys Smad2/3 transcription factors to control cellular responses.Failure or dysregulation in t...
关键词：TGFBR receptor Smads THROMBOSPONDINS matrix metalloproteinases INTEGRINS TRANSACTIVATION 
The protective roles of integrin α4β7 and Amphiregulin-expressing innate lymphoid cells in lupus nephritis
《Cellular & Molecular Immunology》2024年第7期723-737,共15页Seungwon Ryu Kyung Ah Kim Jinwoo Kim Dong Hun Lee Yong-Soo Bae Hajeong Lee Byoung Choul Kim Hye Young Kim 
supported by grants from the National Research Foundation of Korea(SRC2017R1A5A1014560,RS-2023-00217798,RS-2023-00211566 and NRF-2022R1A2C3007730)。
Type 2 innate lymphoid cells (ILC2s) have emerged as key regulators of the immune response in renal inflammatory diseases such as lupus nephritis. However, the mechanisms underlying ILC2 adhesion and migration in the ...
关键词：Innate lymphoid cells Tissue residency Adhesion molecules INTEGRINS Kidney Lupus nephritis AMPHIREGULIN 
Integrins and their potential roles in mammalian pregnancy被引量：1
《Journal of Animal Science and Biotechnology》2024年第1期1-19,共19页Gregory A.Johnson Robert C.Burghardt Fuller W.Bazer Heewon Seo Joe W.Cain 
supported by USDA-NRICGP 98-35203-6337 to FWB.and RCB,NRSA DHHS/NIH 1-F32-HDO 8501 O1A1 to GAJ,USDA-NRI 2006-35203-17199 to GAJ and Kayla J.Bayless;USDA National Institute of Food and Agriculture Research Initiative Competitive Fellowship Grant no.2012-67011-19892 to James W.Frank and GAJ;Agriculture and Food Research Initiative Competitive Grant no.2016-67015-24955 from the USDA National Institute of Food and Agriculture to GAJ and FWB;National Institutes of Health Grant 1R21HD071468-01 to GAJ and KJB。
Integrins are a highly complex family of receptors that, when expressed on the surface of cells, can mediate reciprocal cell-to-cell and cell-to-extracellular matrix(ECM) interactions leading to assembly of integrin a...
关键词：Humans Implantation INTEGRINS PIGS PREGNANCY RODENTS SHEEP 
全选清除导出
共6页<123456>
检索报告 对象比较 聚类工具 使用帮助 返回顶部