NEUROTOXIC

作品数：21被引量：39H指数：3
导出分析报告
相关领域：医药卫生更多>>
相关作者：喻志强潘建义孙晓红冯昱李蕾更多>>
相关机构：长崎大学浙江理工大学中国医科大学更多>>
相关期刊：《Zoological Research》《Journal of Environmental Sciences》《Signal Transduction and Targeted Therapy》《World Journal of Neurology》更多>>
相关基金：国家自然科学基金天津市自然科学基金安徽省自然科学基金浙江省教育厅科研计划更多>>
-
在结果中检索

检索结果分析

结果分析中...
共 条 记 录，以下是1-10
全选清除导出
参考文献引证文献引用追踪
视图：
排序：
Dual effects of GABA_(A)R agonist anesthetics in neurodevelopmentnd vulnerable brains:From neurotoxic to therapeutic effects
《Neural Regeneration Research》2026年第1期81-95,共15页Dihan Lu Wen Zhang Keyu Chen Xia Feng 
Debates regarding the specific effects of general anesthesia on developing brains have persisted for over 30 years.A consensus has been reached that prolonged,repeated,high-dose exposure to anesthetics is associated w...
关键词：brain central nervous system cognition gamma-aminobutyric acid type A receptor agonist general anesthetics neurogenesis neurological disorders neuroprotection NEUROTOXICITY signal pathways 
Impacts of PI3K/protein kinase B pathway activation in reactive astrocytes: from detrimental effects to protective functions
《Neural Regeneration Research》2025年第4期1031-1041,共11页Ramón Pérez-Núñez María Fernanda González Ana María Avalos Lisette Leyton 
supported by Fondo Nacional de Desarrollo Científico y Tecnológico(FONDECYT)#1200836,#1210644,and#1240888,and Agencia Nacional de Investigación y Desarrollo(ANID)-FONDAP#15130011(to LL);FONDECYT#3230227(to MFG).
Astrocytes are the most abundant type of glial cell in the central nervous system.Upon injury and inflammation,astrocytes become reactive and undergo morphological and functional changes.Depending on their phenotypic ...
关键词：inflammation INTEGRINS NEUROPROTECTIVE NEUROTOXIC phosphatidylinositol 3-kinase reactive astrocytes signal transduction Thy-1(CD90) 
Overexpression of low-density lipoprotein receptor prevents neurotoxic polarization of astrocytes via inhibiting NLRP3 inflammasome activation in experimental ischemic stroke被引量：2
《Neural Regeneration Research》2025年第2期491-502,共12页Shuai Feng Juanji Li Tingting Liu Shiqi Huang Xiangliang Chen Shen Liu Junshan Zhou Hongdong Zhao Ye Hong 
supported by the National Natural Science Foundation of China,No.82201460(to YH);Nanjing Medical University Science and Technology Development Fund,No.NMUB20210202(to YH).
Neurotoxic astrocytes are a promising therapeutic target for the attenuation of cerebral ischemia/reperfusion injury.Low-density lipoprotein receptor,a classic cholesterol regulatory receptor,has been found to inhibit...
关键词：inflammation ischemia/reperfusion injury ischemic stroke low-density lipoprotein receptor neuroprotective astrocytes neurotoxic astrocytes NLRP3 inflammasome POLARIZATION 
Drosophila X virus-like particles as delivery carriers for improved oral insecticidal efficacy of scorpion Androctonus australis peptide against the invasive fruit fly,Drosophila suzukii被引量：1
《Insect Science》2024年第3期847-858,共12页Qi Xue Luc Swevers Clauvis Nji Tizi Taning 
supported by the Special Research Fund of Ghent University and Research Foundation Flanders(FWO).CNTT is recipient of a senior postdoctoral fellowship from FWO(grant number 12V5722N).
Insect-specific neurotoxic peptides derived from the venoms of scorpions and spiders can cause acute paralysis and death when injected into insects,offering a promising insecticidal component for insect pest control.H...
关键词：AalT Drosophila suzuki NANOCARRIER neurotoxic peptides pest control virus-like particle(VLP) 
The SARS-CoV-2 main protease induces neurotoxic TDP-43 cleavage and aggregates
《Signal Transduction and Targeted Therapy》2023年第4期1364-1367,共4页Jiaxin Yang Yan Li Shijin Wang Huili Li Lili Zhang Haichen Zhang Pei-Hui Wang Xiangyu Zheng Xiao-Fang Yu Wei Wei 
Dear Editor,Neurologic manifestations associated with many COVID-19 patients,including acute infection with severe acute respiratory syndrome coronavirus-2(SARS-CoV-2)and long COVID,have been proven by increasing evid...
关键词：ACUTE INFECTION RESPIRATORY 
Assessment of risks, implications, and opportunities of waterborne neurotoxic pesticides
《Journal of Environmental Sciences》2023年第3期735-741,共7页Delaram Dara Andrei P.Drabovich 
Pesticides are a well-known family of chemicals that have contaminated water systems globally. Four common subfamilies of pesticides include organochlorines, organophosphates, pyrethroids, and carbamate insecticides w...
关键词：Neurotoxic pesticides Water pollution Neural stem cells Omics approaches Drug discovery 
Drosophila melanogaster as an indispensable model to decipher the mode of action of neurotoxic compounds
《BIOCELL》2023年第1期51-69,共19页MONALISA MISHRA PUNYATOYA PANDA BEDANTA KUMAR BARIK AMRITA MONDAL MRUTUNJAYA PANDA 
MM Lab is supported by SERB/EMR/2017/003054,BT/PR21857/NNT/28/1238/2017;Odisha DBT 3325/ST(BIO)-02/2017.
Exposure to some toxic compounds causes structural and behavioral anomalies associated with the neurons in the later stage of life.Those toxic compounds are termed as a neurotoxicant,which can be a physical factor,a t...
关键词：Developmental cycle Drug metabolism NEUROTOXICITY Neurotoxicants Complex behavioral assay Stress enzymes 
Maraviroc promotes recovery from traumatic brain injury in mice by suppression of neuroinflammation and activation of neurotoxic reactive astrocytes被引量：13
《Neural Regeneration Research》2023年第1期141-149,共9页Xi-Lei Liu Dong-Dong Sun Mu-Tian Zheng Xiao-Tian Li Han-Hong Niu Lan Zhang Zi-Wei Zhou Hong-Tao Rong Yi Wang Ji-Wei Wang Gui-Li Yang Xiao Liu Fang-Lian Chen Yuan Zhou Shu Zhang Jian-Ning Zhang 
supported by grants from the National Natural Science Foundation of China, Nos. 81930031 (to JNZ), 81720108015 (to JNZ), 81901525 (to SZ), 82101440 (to DDS), 81801234 (to YZ) and 82071389 (to GLY);the Natural Science Foundation of Tianjin, Nos. 20JCQNJC01270 (to JWW), 20JCQNJC00460 (to GLY), 18JCQNJC81000 (to HTR);Scientific Research Project of Tianjin Education Commission (Natural Science), No. 2018KJ052 (to ZWZ);Tianjin Health and Health Committee Science and Technology Project, No. QN20015 (to JWW);the Science & Technology Development Fund of Tianjin Education Commission for Higher Education, No. 2016YD02 (to YW);Tianjin Key Science and Technology Projects of Innovative Drugs and Medical Devices, No. 19ZXYXSY00070 (to YW);the Clinical Research Fundation of Tianjin Medical University, No. 2018kylc002 (to YW)
Neuroinflammation and the NACHT,LRR,and PYD domains-containing protein 3 inflammasome play crucial roles in secondary tissue damage following an initial insult in patients with traumatic brain injury(TBI).Maraviroc,a ...
关键词：C-C chemokine receptor type 5(CCR5)antagonist high mobility group protein B1(HMGB1) MARAVIROC M1 microglia nuclear factor-κB pathway NACHT LRR and PYD domains-containing protein 3(NLRP3)inflammasome NEUROINFLAMMATION neurological function neurotoxic reactive astrocytes traumatic brain injury 
Propofol Protects Regulatory T Cells, Suppresses Neurotoxic Astrogliosis, and Potentiates Neurological Recovery After Ischemic Stroke被引量：3
《Neuroscience Bulletin》2021年第5期725-728,共4页Yuzhu Wang Dan Tian Yushang Zhao Mengyao Qu Yuhualei Pan Changwei Wei Yanbing Zhu Anshi Wu 
supported by the National Natural Science Foundation of China (81771139);Beijing Natural Science Foundation (7194270)。
Dear Editor,Emergency intravascular thrombectomy is the best treatment for acute ischemic stroke [1]. However, it is controversial whether the use of general anesthesia during emergency intravascular thrombectomy affe...
关键词：ANESTHESIA acute INTRAVASCULAR 
Neural stem cell-based in vitro bioassay for the assessment of neurotoxic potential of water samples被引量：1
《Journal of Environmental Sciences》2021年第3期72-86,共15页Muhammad Irfan Masood Natalie Tamara Hauke Muhammad Jawad Nasim Muhammad Sarfraz Mahrukh Naseem Karl Herbert Schäfer 
the Higher Education Commission(HEC),Pakistan(Ref.PD/OS-II/Batch-VI/Germany/2015/77159/17755);the University of Applied Sciences Kaiserslautern,Germany for providing financial support to execute the present project。
Intensive agriculture activities,industrialization and growing numbers of wastewater treatment plants along river banks collectively contribute to the elevated levels of neurotoxic pollutants in natural water reservoi...
关键词：Neural stem cells Subventricular zone NEUROTOXICITY BIOASSAY Treated sewage effluents PESTICIDES 
全选清除导出
共3页<123>
检索报告 对象比较 聚类工具 使用帮助 返回顶部