supported by the National Key Research and Development Program of China(Nos.2023YFC2307305,2021YFF0703300);the Shenzhen Medical Research Fund(No.B2303003);Shenzhen Research Funding Program(Nos.JCYJ20220818102014028,RCBS20210609104339043);National Natural Science Foundation of China(No.22174167);Guangdong Basic and Applied Basic Research(No.2024A1515011281);Fundamental Research Funds for the Central Universities(No.24qnpy087)from Sun Yat-sen University。
Ultrasensitive detection of nucleic acids is of great significance for precision medicine.Digital polymerase chain reaction(dPCR)is the most sensitive method but requires sophisticated and expensive instruments and a ...
supported by the National Key Research and Development Program of China(NO.2023YFD1301505,No.2017YFC1600303);the Agricultural Science and Technology Innovation Program of CAAS(CAAS-ASTIP-IQSTAP-04);Prof.Giesy was supported by the Canada Research Chair program,the 2012"High Level Foreign Experts"(#GDT20143200016)program,funded by the State Administration of Foreign Experts Affairs,the P.R.China to Nanjing University and the Einstein Professor Program of the Chinese Academy of Sciences and a Distinguished Visiting Professorship in the Department of Environmental Sciences,Baylor University in Waco,TX,USA.
Emerging synthetic or derivative chemicals have drawn global concern due to their potential endocrine-disrupting effects,either as agonists or antagonists or through indirect effects on enzymes of signal transduction ...
supported by University Grants Commission-Rajiv Gandhi National Fellowship[F1-17.1/2016-17/RGNF-2015-17-SC-AND 6017/(SAIII/Website)].
Objective:To evaluate the cardioprotective effect of bioassay-guided isolated fractions of Cleome viscosa methanolic extract in streptozotocin-induced diabetic rats.Methods:Total phenolics,flavonoids,and in vitro anti...
National Natural Science Foundation of China,Grant/Award Numbers:22302231,21902024,82102511,22104154,82102181;Guangdong Basic and Applied Basic Research Foundation,Grant/Award Number:2023A1515011986;Natural Science Foundation of Jiangsu,Grant/Award Numbers:BK20210021,BE20210009,BK20200568;Research Project of Jiangsu Province Health Committee,Grant/Award Number:M2021031;Shenzhen Fundamental Research Program,Grant/Award Number:JCYJ20190808120405672;Futian Healthcare Research Project,Grant/Award Numbers:FTWS2022013,FTWS2023080;Fundamental Research Funds for the Central Universities,Sun Yat-sen University,Grant/Award Number:23qnpy153;Fundamental Research Funds for the Central Universities,Grant/Award Number:2242021R41178;Funding for Clinical Trials from the Affiliated Drum Tower Hospital,Medical School of Nanjing University,Grant/Award Number:2022-LCYJ-PY-05;Shenzhen Medical Academy of Research and Translation Program,Grant/Award Number:A2303017。
Colloidal crystals are materials self-assembled from the colloidal nanoparticles.Due to the ordered microstructure,they exhibit significant optical properties and have shown huge potential in the field of biosensing.B...
Background Chitinase is an enzyme that hydrolyzes chitin,a major component of the exoskeleton of insects,including plant pests like whiteflies.The present study aimed to investigate the expression of chemically synthe...
This project was supported by the Natural Science Foundation of Zhejiang province(No.LY20H300004);the National Natural Science Foundation of China(Nos.82073686,81730108,and 81973635);Scientific Research Foundation for Scholars of HZNU(Nos.2021QDL026 and 2019QDL003);the Ministry of Science and Technology of China(High-end foreign experts program,Nos.G20200217005 and G2021017004).
Natural products are essential sources of antitumor drugs.One such molecule,β-elemene,is a potent antitumor compound extracted from Curcuma wenyujin.In the present investigation,a series of novel 13,14-disubstituted ...
supported by the National Natural Science Foundation of China(Nos.22275068,21975178);the Open Project of the State Key Laboratory of Supramolecular Structure and Materials,China.
Biosensors based on organic field-effect transistors(OFETs)are one of the most promising electronic devices for emerging bioanalytical applications.The selection of organic semiconductors(OSCs)is essential to improve ...
This work was financially supported by the Natural Science Foundation of China(Nos.21877039,32072441);National Key Research and Development Program of China(No.2018YFD0200100);Innovation Program of Shanghai Municipal Education Commission(No.2017-01-07-00-02-E00037).
Precise and spatiotemporal control over the pesticide remains to be a challenge.More efficient controlled release systems(CRSs)have been developed to support the precise delivery of active ingredients.Herein,we incorp...
supported by the National Natural Science Foundation of China(No.32270413,U1812403);the Science and Technology Department of Guizhou Province(No.QKH 2020-1Z076);the 13th batch of Outstanding Young Scientific and Technological Talents in Guizhou Province(No.QKHPTRC[2021]5633);Cultivation project of National Natural Science Foundation of Guizhou Medical University(No.19NSP003);the Education Department of Guizhou Province(No.QJH KY[2021]189);the Natural Science Foundation of Guizhou Province(No.QKHZYD[2022]4015);High-level Innovative Talents in Guizhou Province(Thousand Levels of Talent for Chunmao Yuan in 2018);“Light of the West”Talent Cultivation Program of Chinese Academy of Sciences for Chunmao Yuan(No.RZ[2020]82).
This study employed the α-glucosidase inhibitory activity model as an anti-diabetic assay and implemented a bioactivity-guided isolation strategy to identify novel natural compounds with potential therapeutic propert...