CARDIOPROTECTION

作品数：78被引量：709H指数：17
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相关机构：陕西师范大学安徽医科大学第二附属医院上海市心血管病研究所第四军医大学西京医院更多>>
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Cardioprotective effect of bioassay-guided fractions of Cleome viscosa methanolic extract in streptozotocin-induced diabetic rats
《Asian Pacific Journal of Tropical Biomedicine》2024年第11期486-499,共14页Suresh Yarrappagaari Lavanya Thopireddy Srinivasulu Cheemanapalli Venkata Ramireddy Narala Rajeswara Reddy Saddala 
supported by University Grants Commission-Rajiv Gandhi National Fellowship[F1-17.1/2016-17/RGNF-2015-17-SC-AND 6017/(SAIII/Website)].
Objective:To evaluate the cardioprotective effect of bioassay-guided isolated fractions of Cleome viscosa methanolic extract in streptozotocin-induced diabetic rats.Methods:Total phenolics,flavonoids,and in vitro anti...
关键词：Cleome viscosa L. CARDIOPROTECTION Cardiac markers DOCKING CK-MB GC-MS Diabetes 
A novel intracoronary hypothermia device reduces myocardial reperfusion injury in pigs
《Chinese Medical Journal》2024年第20期2461-2472,共12页Zhiqiang Pei Jin Qiu Yongchao Zhao Shuai Song Rui Wang Wei Luo Xingxing Cai Bin Liu Han Chen Jiasheng Yin Xinyu Weng Yizhe Wu Chenguang Li Li Shen Junbo Ge 
supported by grants from the National Natural Science Foundation of China(No.82170342);Shanghai Engineering Research Center of Interventional Medicine(No.19DZ2250300);National Key R&D Program of China(No.2021YFA1201300);Chinese Academy of Medical Sciences(Nos.2019-I2M-5-060 and 2020-JKCS-0154020);the Fellowship of the China National Postdoctoral Program for Innovative Talents(No.BX20220094);China Postdoctoral Science Foundation(No.2022M710776);Shanghai Shenkang Hospital Development Center(No.SHDC2020CR3023B).
Background:Hypothermia therapy has been suggested to attenuate myocardial necrosis;however,the clinical implementation as a valid therapeutic strategy has failed,and new approaches are needed to translate into clinica...
关键词：Acute myocardial infarction CARDIOPROTECTION HYPOTHERMIA Inflammation Left ventricular systolic function Percutaneous coronary intervention Cardiac magnetic resonance imaging 
Beyond cardiomyocytes:Cellular diversity in the heart's response to exercise
《Journal of Sport and Health Science》2023年第4期423-437,F0003,共16页Lena E.Trager Margaret Lyons Alexandra Kuznetsov Cedric Sheffield Kangsan Roh Rebecca Freeman James Rhee J.Sawalla Guseh Haobo Li Anthony Rosenzweig 
Supported by the NIH(R01AG061034(AR),R35HL15531(AR),R21AG077040(HL),and K08HL140200(JR));the American Heart Association(20CDA35310184(HL)and 19AMFDP34990046(JSG));Sarnoff Cardiovascular Research Foundation Fellowship award(LET and CS);Massachusetts General Hospital Sanchez-Ferguson Faculty Scholar Program(JSG)。
Cardiomyocytes comprise~70%to 85%of the total volume of the adult mammalian heart but only about 25%to 35%of its total number of cells.Advances in single cell and single nuclei RNA sequencing have greatly facilitated ...
关键词：ANGIOGENESIS Cardiac fibrosis CARDIOPROTECTION HYPERTROPHY Non-cardiomyocytes Proliferation 
Research Progress in Finerenone in Cardiovascular Diseases
《Cardiovascular Innovations and Applications》2023年第1期516-526,共11页Sun Xue Dong Yanghong Gu Jiaxin Liu Wenxiu Liu Yue 
This review was supported by the National Natural Science Foundation of China(81700318);Natural Science Foundation of Heilongjiang Province(JJ2023LH1159);Heilongjiang Postdoctoral Scientific Research Developmental Fund(LBHQ21109);Innovation and Entrepreneurship Training Program for College Students of Harbin Medical University(S202110226068);Doctor Funds of the First Affiliated Hospital of Harbin Medical University(201613007).
Mineralocorticoid receptor antagonists(MRA)have significant therapeutic effects on heart failure,hypertension,chronic kidney disease and primary aldosteronism.However,steroid MRA can cause hyperkalemia,deterioration o...
关键词：finerenone non-steroidal MRA cardiovascular disease CARDIOPROTECTION 
In vitro binding capacities, physicochemical properties and structural characteristics of polysaccharides fractionated from Passiflora edulis peel被引量：3
《Food Bioscience》2022年第6期1284-1295,共12页Yongjin Sun Ke Yang Xin Zhang Lifen Li Huixiang Zhang Li Zhou Jun Liang Xia Li 
supported by the National Natural Science Foundation of China(31860251);the Natural Science Foundation of Guangxi Province(2021GXNSFAA220072);the Guangxi Key Laboratory of Electrochemical and Magneto-chemical Functional Materials(EMFM20211104);the Guangxi Science&Technology Program(AD20297088).
This study aimed to determine structural characteristics, physical properties and binding effects of polysaccharide and its fractions from Passiflora edulis peel on lipid, cholesterol and bile acids. The crude polysac...
关键词：Passiflora edulis POLYSACCHARIDE Structural characteristics Binding capacity CARDIOPROTECTION 
Beclin1 haploinsufficiency compromises mesenchymal stem cell-offered cardioprotection against myocardial infarction
《Cell Regeneration》2022年第1期192-202,共11页Xing Qin Juanjuan Fei Yu Duan Asli F.Ceylan Fuyang Zhang Jun Ren 
This work was supported in part by a grant from Natural Science Foundation of China(91749128).
Mesenchymal stem cells(MSCs)-based therapy has displayed some promises in ischemia heart diseases although its efficacy may be affected by changes in surrounding environments.This study evaluated the role of autophagy...
关键词：Myocardial infarction MSCs BECLIN1 CONTRACTION Apoptosis Autophagy 
Effects of Chios mastic gum on cardiometabolic risk factors
《World Journal of Diabetes》2022年第11期921-925,共5页Athanasia K Papazafiropoulou 
Chios mastic gum(CMG),the resin produced by the trunk of Pistachia lentiscus var Chia,has been used for culinary and medicinal purposes since antiquity.Despite the fact that Pistacia species are widely distributed thr...
关键词：Chios mastic gum GLUCOSE CARDIOPROTECTION Low-density lipoproteincholesterol TRIGLYCERIDES 
Effect of Xuebijing injection on myocardium during cardiopulmonary bypass:A prospective,randomized,double blind trial被引量：6
《World Journal of Clinical Cases》2022年第13期4110-4118,共9页Zhe-Hao Jin Xiao-Qing Zhao Hai-Bin Sun Jing-Li Zhu Wei Gao 
BACKGROUND Cardiopulmonary bypass(CPB)is an essential procedure for maintaining the blood supply to vital organs in patients undergoing cardiac surgery.However,perioperative cardiac injury related to CPB remains a sev...
关键词：Xuebijing injection Cardiopulmonary bypass Cardiac injury CARDIOPROTECTION Circulating inflammation Oxidative stress 
Cardioprotective mechanism of SGLT2 inhibitor against myocardial infarction is through reduction of autosis被引量：28
《Protein & Cell》2022年第5期336-359,共24页Kai Jiang Yue Xu Dandan Wang Feng Chen Zizhuo Tu Jie Qian Sheng Xu Yixiang Xu John Hwa Jian Li Hongcai Shang Yaozu Xiang 
Y Xiang received support from the National Key Research and Development Program of China(2017YFC1700402);National Outstanding Youth Science Fund Project of National Natural Science Foundation of China(81822048 and 81770256);Fund of Shanghai Pudong New Area(PDZY-2018-0603).
Sodium-glucose cotransporter 2(SGLT2)inhibitors reduce cardiovascular mortality in patients with diabetes mellitus but the protective mechanism remains elusive.Here we demonstrated that the SGLT2 inhibitor,Empaglifloz...
关键词：myocardial infarction SGLT2 inhibitors empagliflozin CARDIOPROTECTION NHE1 autosis 
Effects of dexmedetomidine on cardioprotection and other postoperative complications in elderly patients after cardiac and non-cardiac surgerie
《World Journal of Meta-Analysis》2022年第1期25-36,共12页Yang-Liang Yang Bao-Ji Hu Jing Yi Meng-Zhi Pan Peng-Cheng Xie Hong-Wei Duan 
BACKGROUND After cardiac and non-cardiac surgeries,elderly patients have a high probability of developing cardiac complications and postoperative delirium.Although several clinical trials have investigated whether per...
关键词：DEXMEDETOMIDINE CARDIOPROTECTION Postoperative delirium COMPLICATION META-ANALYSIS 
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