supported by National Key R&D Program of China(2020YFA0908000);the CACMS Innovation Fund(CI2021A04109,CI2023D002,China);Key project at central government level:the ability to establish sustainable use of valuable Chinese Medicine Resources(2060302,China).
(+)-Borneol,the main component of"Natural Borneol"in the Chinese Pharmacopoeia,is a high-end spice and precious medicine.Plant extraction cannot meet the increasing demand for(+)-borneol,while microbial biosynthesis o...
supported by National Key Research and Development Program of China(2020YFA0908000);Prof.Zhubo Dai was supported by Youth Innovation Promotion Association of CAS(2015138);Haihe Laboratory Disruptive Innovation Talent Program(22HHSWSS00026);supported by the Key Project at Central Government Level:The ability establishment of sustainable use for valuable Chinese medicine resources(2060302)。
Background:Heterologous synthesis presents a promising new approach for accessing the active ingredients of traditional Chinese medicine(TCM),contributing to the conservation of natural medicinal resources.Compound Da...
supported by the National Key R&D Program of China(2023YFA0913900);the Shenzhen Medical Research Fund(A2303026);the Shenzhen Science and Technology Program(KJZD20230923114415032).
Saccharomyces cerevisiae,a widely utilized model organism,has seen continuous updates to its genome-scale metabolic model(GEM)to enhance the prediction performance for metabolic engineering and systems biology.This st...
funded by the National Natural Science Foundation of China(grant no.32260760);the Science and Technology Program of Guizhou Province(grant no.20201Z002);the Platform Construction Project of Engineering Research Center for Protected Vegetable Crops in Higher Learning Institutions of Guizhou Province(Qianjiaoji[2022]No.040).
Hot pepper(Capsicum annuum var.conoides)is a significant vegetable that is widely cultivated around the world.Currently,global climate change has caused frequent severe weather events,and waterlogging stress harms the...
supported by the Zhejiang Provincial Natural Science Foundation of China(No.LR21C070001);the National Natural Science Foundation of China(Nos.32122028,92254307,32070739,and 32100600)。
Autophagy plays a crucial role in maintaining cellular homeostasis in response to various stimuli.Compared to research on nutrient deprivation-induced autophagy,the understanding of the molecular mechanisms and physio...
Mutagens are agents that cause damage to DNA and have the potential to permanently alter (mutate) its sequence, depending on the organism’s ability to repair the damage. UV radiation is a mutagen in cells. This mutag...
supported by the National Key Research and Development Program of China(NO.2023YFD1301505,No.2017YFC1600303);the Agricultural Science and Technology Innovation Program of CAAS(CAAS-ASTIP-IQSTAP-04);Prof.Giesy was supported by the Canada Research Chair program,the 2012"High Level Foreign Experts"(#GDT20143200016)program,funded by the State Administration of Foreign Experts Affairs,the P.R.China to Nanjing University and the Einstein Professor Program of the Chinese Academy of Sciences and a Distinguished Visiting Professorship in the Department of Environmental Sciences,Baylor University in Waco,TX,USA.
Emerging synthetic or derivative chemicals have drawn global concern due to their potential endocrine-disrupting effects,either as agonists or antagonists or through indirect effects on enzymes of signal transduction ...
supported by the Natural Science Foundation of Hunan Province,China(Grant No.2023JJ30997);the National Key Research and Development Program of China(Grant No.2022YFD2101303);the Hunan Science and Technology Innovation Plan,China(Grant No.2023ZJ1070);the Local Fund for Science and Technology Development Guided by the Central Government,China(Grant No.2023ZYC008);the Hunan Forestry Science and Technology Research and Innovation Fund Project,China(Grant No.XLKY202326);the Scientific Research Project of Central South University of Forestry and Technology,China(Grant No.2022ZK3042)。
To address the coarse texture and poor cooking quality of brown rice flour,we employed fermentation using lactobacillus and yeast in varying proportions.The fermented flour from early indica rice Pear 13 was then proc...
supported by the National Natural Science Foundation of China (82100863);Hebei Natural Science Foundation (H2020206643 and H2020206105);Funding project for introducing overseas students of Hebei Province (C20210346);Medical Science Research Project of Hebei Province (20211628);Hebei Province Government-funded Excellent Talents Project in Clinical Medicine (ZF2023029);Spark Scientific Research Project of the First Hospital of Hebei Medical University (XH202004).
Excessive secretion of human islet amyloid polypeptide(hIAPP)is an important pathological basis of diabetic encephalopathy(DE).In this study,we aimed to investigate the potential implications of hIAPP in DE pathogenes...
funded by National Natural Science Foundation of China (NSFC 32330110 and 31925038).
This study aimed to investigate the effects of solid-state fermentation products of yeast(SFPY)on liver and intestinal health and disease resistance of common carp(Cyprinus carpio).A total of 200 common carp with an i...