NANOCARRIER

作品数：116被引量：347H指数：7
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相关机构：北京大学中国农业大学复旦大学中山大学更多>>
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Nanocarrier-mediated siRNA delivery:a new approach for the treatment of traumatic brain injury-related Alzheimer's disease
《Neural Regeneration Research》2025年第9期2538-2555,共18页Jie Jin Huajing Zhang Qianying Lu Linqiang Tian Sanqiao Yao Feng Lai Yangfan Liang Chuanchuan Liu Yujia Lu Sijia Tian Yanmei Zhao Wenjie Ren 
supported by Open Project of the Key Laboratory of Trauma and Orthopedics Research Medicine in Henan Province,No.HZKFKT20220504(to YZ);the National Natural Science Foundation of China,No.32000877(to YZ);and Open Scientific Research Program of Military Logistics,No.BLB20J009(to YZ)。
Traumatic brain injury and Alzheimer's disease share pathological similarities,including neuronal loss,amyloid-βdeposition,tau hyperphosphorylation,blood-brain barrier dysfunction,neuroinflammation,and cognitive defi...
关键词：blood-brain barrier cognitive dysfunction EXOSOMES gene silencing immunotherapy inorganic nanomaterials liposome nanoparticles NEUROINFLAMMATION polymer nanoparticles stem cells 
Ferritin nanocage loading lycopene for improving blood-brain barrier transcytosis and attenuating D-galactose-induced apoptosis in PC12 cells
《Food Science and Human Wellness》2025年第3期880-891,共12页Xiaoyu Xia Han Li Xianbing Xu Zhenyu Wang Junjie Yi Guanghua Zhao Ming Du 
financially supported by the National Natural Science Foundation of China(31730069);Graduate Innovation Fund of Dalian Polytechnic University。
Aging is a physiological process that leads to degeneration and functional decline of the brain.This is accompanied by intracellular peroxidation and neuronal apoptosis.Natural antioxidants possess a remarkable effect...
关键词：FERRITIN LYCOPENE NANOCARRIER Neuroprotection Aging 
Identification of a TOR signaling pathway gene as a candidate target for reproductive management of Adelphocoris suturalis
《Journal of Integrative Agriculture》2025年第4期1529-1541,共13页Wanying Zheng Panyang Jiao Xiaona Xu Weihua Ma J.Joe Hull Hongxia Hua Lizhen Chen 
supported by the National Natural Science Foundation of China(32072428)。
Adelphocoris suturalis is a polyphagous pest that is increasingly causing severe economic damage due to more frequent outbreaks.The development of non-target resistance to commercial Bacillus thuringiensis(Bt)cotton h...
关键词：Adelphocoris suturalis target of rapamycin(TOR)signaling reproductive regulation RNAi targets nanocarrier-mediated RNAi 
Probable Molecular Targeting of Inhibitory Effect of Carvacrol-Loaded Bovine Serum Albumin Nanoparticles on Human Breast Adenocarcinoma Cells
《Chinese Journal of Integrative Medicine》2025年第4期336-346,共11页Pouria Khodavandi Neda Karami Alireza Khodavandi Fahimeh Alizadeh Esmaeel Panahi Kokhdan Ahmad Zaheri 
Objective:To entrap carvacrol(CAR)in bovine serum albumin nanoparticles(BSANPs)to form CAR-loaded BSANPs(CAR@BSANPs)and to explore the anti-cancer effects in breast adenocarcinoma cells(MCF-7 cells)treated with CAR an...
关键词：breast cancer CARVACROL gene expression NANOCARRIER NANOPARTICLES MCF-7 cell 
Coffee-derived self-anti-inflammatory polymer as drug nanocarrier for enhanced rheumatoid arthritis treatment
《Chinese Chemical Letters》2025年第3期371-378,共8页Chunlei Dai Liying Wang Xinru You Yi Zhao Zhong Cao Jun Wu 
supported by the National Natural Science Foundation of China(No.52173150);the Guangzhou Science and Technology Program City University Joint Funding Project(No.2023A03J0001)to Jun Wu;supported by the National Natural Science Foundation of China(No.52073313);Shenzhen Science and Technology Program(No.KCXFZ 202002011010232);Longhua District Science and Innovation Commission Project Grants of Shenzhen(No.10162A20221027B1FA526)to Zhong Cao;supported by Shenzhen Medical Research Fund(No.A2303010);National Natural Science Foundation of China(No.82204287);Fundamental Research Funds for the Central Universities,Sun Yat-sen University(No.87000-31670001)to Yi Zhao;supported by Guangdong Basic and Applied Basic Research Foundation(No.2023A1515220126)to Xinru You。
Systemic administration of the anti-rheumatic drug methotrexate(MTX)for a long period of time may lead to therapeutic tolerance,various adverse effects,and potential harm to the immune system.Therapeutic nano-delivery...
关键词：Rheumatoid arthritis Caffeic acid Self-anti-inflammatory polymer NANOCARRIER METHOTREXATE 
An Intelligent Triple Assisted Gold Cluster-Based Nanosystem for Enhanced Tumor Photodynamic Therapy
《Chinese Journal of Chemistry》2025年第2期175-183,共9页Fangli Gao Yanru Liu Liang Zhu Jie Zhang Yi Chang Weihua Gao Guanglei Ma Xiaoming Ma Yuming Guo 
financially supported by the National Natural Science Foundation of China(21771058 and 21877027);the Natural Science Foundation of Henan Province(242300421205,212300410009,and 232300421302);the 111 Project(D17007),the Program for Science&Technology Innovation Talents in Universities of Henan Province(23HASTIT002);the Foundation of Henan Educational Committee(23A150021).
Photodynamic therapy (PDT) has been attracted a surge of research interest. However, there are several obstacles to limit the efficacy of PDT, such as hypoxic tumor microenvironment (TME), overexpressed glutathione (G...
关键词：Gold nanoclusters Diselenide-bridged mesoporous silica nanoparticles HYPOXIA Photodynamic therapy CATALASE GSH consuming Mitochondrial targeting Tumor therapy Bioinorganic chemistry Cancer treatment Drug nanocarrier 
Nanomedicine:The new trend and future of precision medicine for inflammatory bowel disease
《Chinese Medical Journal》2024年第24期3073-3082,共10页Huanyu Li Meng Pan Yifan Li Hao Liang Manli Cui Mingzhen Zhang Mingxin Zhang 
This work was supported by grants from the National Natural Science Foundation of China(No.82472127);Shaanxi Province Key Research and Development Program(Nos.2023-YBSF-072 and 2024JC-YBMS-664);The Innovation Team of Xi’an Medical University(No.2021TD15);Xi’an Science and Technology Plan Project(No.24YXYJ0143);2024 Shaanxi Provincial Health Commission High level Talent Cultivation Project.
Nanomedicine is an interdisciplinary area that utilizes nanoscience and technology in the realm of medicine.Rapid advances in science and technology have propelled the medical sector into a new era.The most commonly u...
关键词：Precision medicine NANOCARRIER Nanozyme Drug nanocrystals Inflammatory bowel disease 
Extracellular vesicles for delivering therapeutic agents in ischemia/reperfusion injury
《Asian Journal of Pharmaceutical Sciences》2024年第6期1-20,共20页Weihang Zhou Xinchi Jiang Jianqing Gao 
This work was supported by the National Natural Science Foundation of China(U22A20383,82003668);the Natural Science Foundation of Zhejiang Province(LD22H300002,LQ21H300002);Ningbo Technology Innovation 2025 Major Special Project(2022Z150).
Ischemia/reperfusion(I/R)injury ismarked by the restriction and subsequent restoration of blood supply to an organ.This process can exacerbate the initial tissue damage,leading to further disorders,disability,and even...
关键词：Extracellular vesicles Extracellular vesicle engineering Ischemia/reperfusion injury NANOCARRIER Drug delivery 
STAT3-specific nanocarrier for shRNA/drug dual delivery and tumor synergistic therapy
《Bioactive Materials》2024年第11期137-157,共21页Le Sun Jishang Sun Cuiyao Li Keying Wu Zhiyang Gu Lan Guo Yi Zhou Baoqin Han Jing Chang 
Shandong Provincial Key Research and Development Program(Major Scientific and Technological Innovation Project,No.2022CXGC010505);National Natural Science Foundation of China(No.51773188);National Key Research and Development Program of China(No.2023YFC2812004);Key Project of Natural Science Foundation of Shandong Province(No.ZR2020KE016).
Non-small cell lung cancer(NSCLC)is a major disease with high incidence,low survival rate and prone to develop drug resistance to chemotherapy.The mechanism of secondary drug resistance in NSCLC chemotherapy is very c...
关键词：Synergistic therapy Short hairpin RNA STAT3 signaling pathway Drug delivery Tumor treatment 
Curcumin delivery nanoparticles based on Maillard reaction of Haematococcus pluvialis protein/galactose for alleviating acute alcoholic liver damage
《Food Science and Human Wellness》2024年第5期2629-2641,共13页Xinyi Liu Yukun Song Shasha Cheng Mingqian Tan 
supported by the National Key Research and Development Program of China(2022YFF1100205);the National Natural Science Foundation of China(31972105);the National Science Fund for Distinguished Young Scholars of China(31925031).
The aim of this study is to investigate the feasibility of Maillard reaction products of Haematococcus pluvialis protein and galactose(HPP-GAL)for improving the bioactivities of curcumin(CUR)for alleviating alcoholic ...
关键词：Haematococcus pluvialis protein GALACTOSE Curcumin nanocarrier Maillard reaction Alcoholic liver damage Liver targeting 
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