Nanomedicine:The new trend and future of precision medicine for inflammatory bowel disease  

作　　者：Huanyu Li Meng Pan Yifan Li Hao Liang Manli Cui Mingzhen Zhang Mingxin Zhang 

机构地区：[1]Second Clinical Medical College,Shaanxi University of Chinese Medicine,Xianyang,Shaanxi 712046,China [2]School of Basic Medical Sciences,Shaanxi University of Chinese Medicine,Xianyang,Shaanxi 712046,China [3]Department of Gastroenterology,The First Affiliated Hospital of Xi’an Medical University,Xi’an,Shaanxi 710077,China [4]School of Basic Medical Sciences,Xi’an Jiaotong University,Xi’an,Shaanxi 710061,China [5]Engineering Research Center of Shaanxi Universities for Innovative Services of Chronic Disease Prevention and Control and Transformation of Nutritional Functional Food,Xi’an,Shaanxi 710077,China

出　　处：《Chinese Medical Journal》2024年第24期3073-3082,共10页中华医学杂志(英文版)

基　　金：This work was supported by grants from the National Natural Science Foundation of China(No.82472127);Shaanxi Province Key Research and Development Program(Nos.2023-YBSF-072 and 2024JC-YBMS-664);The Innovation Team of Xi’an Medical University(No.2021TD15);Xi’an Science and Technology Plan Project(No.24YXYJ0143);2024 Shaanxi Provincial Health Commission High level Talent Cultivation Project.

摘　　要：Nanomedicine is an interdisciplinary area that utilizes nanoscience and technology in the realm of medicine.Rapid advances in science and technology have propelled the medical sector into a new era.The most commonly used nanotechnology in the field of medicine is nanoparticles.Due to their unique physicochemical properties,nanoparticles offer significant benefits of precision medicine for diseases such as inflammatory bowel disease that cannot be effectively treated by existing approaches.Nanomedicine has emerged as a highly active research field,with extensive scientific and technological studies being carried out,as well as growing international competition in the commercialization of this field.The accumulation of expertise in the key technologies relating to nanomedicine would provide strategic advantages in the development of cutting-edge medical techniques.This review presented a comprehensive analysis of the primary uses of nanoparticles in medicine,including recent advances in their application for the diagnosis and treatment of inflammatory bowel disease.Furthermore,we discussed the challenges and possibilities associated with the application of nanoparticles in clinical settings.

关 键 词：Precision medicine NANOCARRIER Nanozyme Drug nanocrystals Inflammatory bowel disease 

分 类 号：R57[医药卫生—消化系统]