THROMBOSPONDINS

作品数:3被引量:5H指数:2
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相关领域:医药卫生更多>>
相关期刊:《Acta Pharmacologica Sinica》《Neural Regeneration Research》更多>>
相关基金:北京市自然科学基金国家自然科学基金国家重点基础研究发展计划广东省自然科学基金更多>>
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Transforming growth factor-β receptors:versatile mechanisms of ligand activation被引量:1
《Acta Pharmacologica Sinica》2024年第7期1337-1348,共12页Zheng-Jie Chia Ying-nan Cao Peter J.Little Danielle Kamato 
supported by a Future Leader Fellowship (106605)from the National Heart Foundation of Australia.
Transforming growth factor-β(TGF-β)signaling is initiated by activation of transmembrane TGF-βreceptors(TGFBR),which deploys Smad2/3 transcription factors to control cellular responses.Failure or dysregulation in t...
关键词:TGFBR receptor Smads THROMBOSPONDINS matrix metalloproteinases INTEGRINS TRANSACTIVATION 
Low-dose nifedipine rescues impaired endothelial progenitor cell-mediated angiogenesis in diabetic mice被引量:2
《Acta Pharmacologica Sinica》2023年第1期44-57,共14页Cheng Peng Lijun Yang Chuan Zhang Yu Jiang Liu-wen-xin Shang Jia-bei He Zhen-wei Zhou Xia Tao Lu Tie Alex F.Chen He-hui Xie 
This work was supported by grants from the Ministry of Science and Technology of China (2021YFA0804803);the National Natural Science Foundation of China (81870189,82070266,81900243,81930012,81730013,92168120 and 81974506);the Beijing Natural Science Foundation(Z200019).
It is of great clinical significance to develop potential novel strategies to prevent diabetic cardiovascular complications.Endothelial progenitor cell(EPC)dysfunction is a key contributor to diabetic vascular complic...
关键词:diabetes NIFEDIPINE endothelial progenitor cells ANGIOGENESIS cerebral ischemia THROMBOSPONDINS 
Thrombospondins and synaptogenesis被引量:2
《Neural Regeneration Research》2012年第22期1737-1743,共7页Bin Wang Weitao Guo Yun Huang 
supported by the Natural Science Foundation of Guangdong Province,No.S2011010004096;the Medical Scientific Research Foundation of Guangdong Province,No.A2010431; A2009477
Here, we review research on the mechanisms underlying the ability of thrombospondin to promote synaptogenesis and examine its role in central nervous system diseases and drug actions. Thrombospondin secreted by glial ...
关键词:THROMBOSPONDIN SYNAPSE SYNAPTOGENESIS glial cell α2δ-1 extracellular matrix neural progenitorcells Notch OPIOID regeneration neural regeneration 
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