THROMBOSPONDIN

作品数：21被引量：43H指数：4
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相关领域：医药卫生更多>>
相关作者：王薇易红艳陈晓静王薇魏文斐更多>>
相关机构：广州医科大学南方医科大学南方医院第二军医大学中南大学更多>>
相关期刊：《Cellular & Molecular Immunology》《Science China(Life Sciences)》《World Journal of Gastroenterology》《Phenomics》更多>>
相关基金：国家自然科学基金深圳市科技计划项目广东省自然科学基金更多>>
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A Genome‑Wide Association Study for Susceptibility to Axial Length in Highly Myopic Eyes被引量：1
《Phenomics》2023年第3期255-267,共13页Qiang Lu Yu Du Ye Zhang Yuxi Chen Hao Li Wenwen He Yating Tang Zhennan Zhao Yinglei Zhang Jihong Wu Xiangjia Zhu Yi Lu 
Funding was provided by the National Natural Science Foundation of China,82122017:Xiangjia Zhu,81970780:Yi Lu,81870642:Xiangjia Zhu,81670835:Yi Lu;Science and Technology Innovation Plan of Shanghai Science and Technology Commission,19441900700:Xiangjia Zhu,21S31904900:Xiangjia Zhu;Shanghai Hospital Development Center,SHDC12019X08:Xiangjia Zhu;Shanghai Shenkang Hospital Development Center,SHDC2020CR4078:Xiangjia Zhu;Double-E Plan of Eye&ENT Hospital,SYA202006:Xiangjia Zhu;Shanghai Municipal Key Clinical Specialty Program,shslczdzk01901:Xiangjia Zhu.
High myopia has long been highly prevalent worldwide with a largely yet unexplained genetic contribution.To identify novel susceptibility genes for axial length(AL)in highly myopic eyes,a genome-wide association study...
关键词：Axial length High myopia Whole-genome sequencing ADAM Metallopeptidase With Thrombospondin Type 1 Motif 16·Phosphatidylinositol Glycan Anchor Biosynthesis Class Z 
Thrombospondin-2 promotes the proliferation and migration of glioma cells and contributes to the progression of glioma被引量：1
《Chinese Neurosurgical Journal》2023年第2期77-87,共11页Tian-Lan Huang Yi-Wen Mei Yang Li Xin Chen Si-Xun Yu Yong-Qin Kuang Hai-Feng Shu 
supported by funds from Scientific and Technological Innovation Talents Project of Sichuan Provincial Science and Technology Department(No.2022JDRC0041);the National Natural Science Foundation of China(No.81772686);Medical Innovation Project(No.21WQ040);Joint Research Project of the General Hospital of Western Theater Command of PLA(No.2019LH01)
Background:Gliomas,especially high-grade gliomas,are highly malignant with a poor prognosis.Although existing treatments have improved the survival rate of patients with glioma,the recurrence and mortality rates are s...
关键词：GLIOMA MIGRATION PROLIFERATION TSP2 
Histidine-rich glycoprotein (HRGP):Pleiotropic and paradoxical effects on macrophage,tumor microenvironment,angiogenesis,and other physiological and pathological processes被引量：1
《Genes & Diseases》2022年第2期381-392,共12页Yixiao Pan Lu Deng Hai Wang Kang He Qiang Xia 
This project is supported by the(No.20204Y0012)Project of Shanghai Municipal Health Commission;National Key R&D Program of China(No.2017YFC0908100);W410170015,Cohort Study of HCC and Liver Diseases,Double First-Class Fundation,Shanghai Jiao Tong University;2017ZZ01018,Overall Leverage Clinical Medicine Center,NHFPC Fundation.
Histidine-rich glycoprotein(HRGP)is a relatively less known glycoprotein,but it is abundant in plasma with a multidomain structure,which allows it to interact with many ligands and regulate various biological processe...
关键词：ANGIOGENESIS Histidine-rich glycoprotein Macrophage polarization THROMBOSPONDIN Tumor 
Cholangiocarcinoma presenting with acquired thrombotic thrombocytopenic purpura confirmed by positive autoantibodies of a disintegrin and metalloproteinase with a thrombospondin type 1 motif,member 13
《Chinese Medical Journal》2020年第12期1495-1496,共2页Yue-Ting Li Han-Ze Du Chun-Yao Wang Tie-Nan Zhu Bo-Ju Pan Lu Zhang 
To the Editor:Thrombotic thrombocytopenic purpura(TTP)is a type of life-threatening thrombotic microangiopathy(TMA)clinically characterized by severe thrombocytopenia,microangiopathic hemolytic anemia,and symptoms of ...
关键词：THROMBOTIC INSUFFICIENCY anemia 
Anti-osteoarthritis effect of a combination treatment with human adipose tissue-derived mesenchymal stem cells and thrombospondin 2 in rabbits被引量：2
《World Journal of Stem Cells》2019年第12期1115-1129,共15页Kyungha Shin Yeseul Cha Young-Hwan Ban Da Woom Seo Ehn-Kyoung Choi Dongsun Park Sung Keun Kang Jeong Chan Ra Yun-Bae Kim 
Supported by Basic Science Research Program through the National Research Foundation of Korea funded by the Ministry of Science and ICT to Y.B.K.,No.2017R1A2A2A05069417
BACKGROUND Osteoarthritis(OA),a chronic age-related disease characterized by the slowly progressive destruction of articular cartilage,is one of the leading causes of disability.As a new strategy for treatment of OA,m...
关键词：Osteoarthritis Anterior CRUCIATE LIGAMENT TRANSECTION HUMAN ADIPOSE tissuederived mesenchymal stem cell THROMBOSPONDIN 2 Notch signaling Cartilage regeneration 
In vivo expression of thrombospondin-1 suppresses the formation of peritoneal adhesion in rats被引量：1
《World Journal of Gastrointestinal Surgery》2019年第2期85-92,共8页Yun-Sheng Tai I-Ming Jou Yun-Chih Jung Chao-Liang Wu Ai-Li Shiau Chih-Yi Chen 
BACKGROUND Formation of intraperitoneal adhesions is one of the major complications after abdominal surgery, which may lead to bowel obstruction. Thrombospondin 1(TSP-1) is an extracellular matrix modulating glycoprot...
关键词：INTRAPERITONEAL ADHESIONS THROMBOSPONDIN 1 RAT model 
THBS2在宫颈癌中的表达及功能研究被引量：6
《现代妇产科进展》2017年第12期889-892,共4页吴湘光 魏文斐 梁莉 王薇 周琛斐 陈晓静 易红艳 刘国炳 钟梅 余艳红 
国家自然科学基金面上项目(No:81072132;81372781;81672589);深圳市科技计划项目(No:JCYJ20160429161218745)
目的:探讨THBS2在宫颈癌发生发展中的表达水平变化以及THBS2对细胞增殖、迁移和侵袭能力的作用。方法:免疫组化和Western blot法检测THBS2在宫颈病变组织及细胞系中的表达水平。选取THBS2表达水平较低的宫颈癌细胞系Si Ha和ME180,通过TH...
关键词：宫颈癌 Thrombospondin-2 增殖 迁移 侵袭 
Levels and activities of von Willebrand factor and metalloproteinase with thrombospondin type-1 motif, number 13 in inflammatory bowel diseases被引量：3
《World Journal of Gastroenterology》2017年第26期4796-4805,共10页Dorota Cibor Danuta Owczarek Saulius Butenas Kinga Salapa Tomasz Mach Anetta Undas 
To evaluate the levels of von Willebrand factor (VWF) and metalloproteinase with thrombospondin type-1 motif, number 13 (ADAMTS13) in inflammatory bowel disease (IBD) and correlate them with the disease activity. METH...
关键词：ADAMTS13 Inflammatory bowel disease THROMBOSIS Acquired von Willebrand syndrome von Willebrand factor 
Circulating thrombospondin-2 in patients with moderate-to-severe chronic heart failure due to coronary artery disease被引量：5
《The Journal of Biomedical Research》2016年第1期32-39,共8页Alexander E.Berezin Alexander A.Kremzer Tatayna A.Samura 
Chronic heart failure（CHF）remains a leading cause of morbidity and mortality.In the current study,we aimed to evaluate the predictive value of circulating fhrombospondin-2（TSP-2）for cumulative survival in patients...
关键词：thrombospondin-2 chronic heart failure survival hospitalization prognosis 
A disintegrin and metalloproteinase with thrombospondin motif 1(ADAMTS1) expression increases in acute aortic dissection被引量：11
《Science China(Life Sciences)》2016年第1期59-67,共9页Yanxiang Gao Wenjing Wu Changan Yu Fangming Zhong Geng Li Wei Kong Jingang Zheng 
supported by the National Natural Science Foundation of China(81170287)
Acute aortic dissection(AAD) is a life-threatening cardiovascular disease caused by progressive medial degeneration of the aortic wall. A disintegrin and metalloproteinase with thrombospondin motifs 1(ADAMTS1) is a re...
关键词：ADAMTS1 acute aortic dissection angiotensin II MACROPHAGE NEUTROPHIL 
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