RAT

作品数：1942被引量：5276H指数：23
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Inhibition of IGF-1Rαaffects the differentiation fate of rat optic cup-derived retinal stem cells to retinal ganglion cells in vitro
《International Journal of Ophthalmology(English edition)》2025年第4期582-589,共8页Qi-You Li Xiao-Ling Tan Hai-Wei Xu Yu-Xiao Zeng Xiao-Yong Huang 
AIM:To explore the impact of insulin-like growth factor-1 receptorα(IGF-1Rα)on the differentiation fate of optic-cupderived retinal stem cells(OC-RSCs)into retinal ganglion cells(RGCs)in vitro.METHODS:OC-RSCs were i...
关键词：insulin-like growth factor-1 receptorα retinal ganglion cell rat optic cup retinal stem cells differentiation fate 
Establishment and characterization of liver-specific Apoa4-C re and Cyp2c11-Cre rat models in juvenile and adult stages
《Animal Models and Experimental Medicine》2025年第4期718-727,共10页Wei Dong Xiang Gao Feifei Guan Jirong Pan Wei Chen Li Zhang Lianfeng Zhang 
CAMS Innovation Fund for Medical Sciences(CIFMS),Grant/Award Number:2021-I2M-1-035;National Natural Science Foundation of China,Grant/Award Number:31970508。
Background:Liver diseases are a major contributor to both morbidity and mortality.Conditional knockout animals are always produced through crossing floxed animals with a tissue-specific Cre animal.The use of floxed ra...
关键词：Apoa4 CRE Cyp2c11 LIVER RAT 
A comparative study of the established methods and evaluation of rat trauma models
《Animal Models and Experimental Medicine》2025年第3期501-510,共10页Zhenmin Sun Jia Sun Gang Su Ruohan Wang Zhaohui Zhai Feng Yu Yuli Li 
Shandong Provincial Natural Science Foundation,Grant/Award Number:ZR2022MH211;the Key Program of Shandong Provincial Natural Science Foundation,Grant/Award Number:ZR2020KE018;National Natural Science Foundation of China,Grant/Award Number:52003068。
Background:Scientific animal models are indispensable for studying trauma repair.This work aimed at establishing a more scientific rat trauma model by studying different rat trauma models caused by different trauma nu...
关键词：age of the rats healing speed modeling rat trauma skin tension unloader 
A rat model of adenoid hypertrophy constructed by using ovalbumin and lipopolysaccharides to induce allergy, chronic inflammation, and chronic intermittent hypoxia
《Animal Models and Experimental Medicine》2025年第2期353-362,共10页Anqi Liu Yixing Zhang Yan Lin Xuejun Li Shuming Wang Wenyan Pu Xiuxiu Liu Zhiyan Jiang Zhen Xiao 
This work was financially supported by the National Natural Science Foundation of China(grant number:8217150152);the Clinical Science and Technology Innovation Project of Shanghai Shenkang Hospital Development Center(grant number:SHDC12021102);the Shanghai Three-Year Action Plan to Further Accelerate the Development of Traditional Chinese Medicine Inheritance and Innovation(grant number:ZY(2021-2023)-0209-05).
Background:Adenoid hypertrophy(AH)is a common pediatric disease that signifi-cantly impacts the growth and quality of life of children.However,there is no replica-ble and valid model for AH.Methods:An AH rat model was...
关键词：allergic rhinitis hypoxia nasopharynx-associated lymphoid tissue rat model of adenoid hypertrophy upper respiratory inflammation 
Effects of Bifidobacterium lactis BLa80 on fecal and mucosal flora and stem cell factor/c-kit signaling pathway in simulated microgravity rats
《World Journal of Gastroenterology》2025年第1期93-109,共17页Ping Zhang Ying Zhu Pu Chen Tong Zhou Zhe-Yi Han Jun Xiao Jian-Feng Ma Wen Ma Peng Zang Ying Chen 
BACKGROUND Simulated microgravity environment can lead to gastrointestinal motility disturbance.The pathogenesis of gastrointestinal motility disorders is closely related to the stem cell factor(SCF)/c-kit signaling p...
关键词：Simulated microgravity RAT Intestinal flora Gastrointestinal motility Stem cell factor/c-kit signaling pathway 
Enhancing tissue regeneration studies with luciferase-transgenic rats and bioluminescence imaging:A comprehensive review
《Chinese Journal of Plastic and Reconstructive Surgery》2024年第4期214-218,共5页Poh-Ching Tan Eiji Kobayashi Qingfeng Li Shuangbai Zhou 
supported by grants from the National Natural Science Foundation of China(grant no.82272287);the Shanghai Clinical Research Center of Plastic and Reconstructive Surgery supported by the Science and Technology Commission of Shanghai Municipality(grant no.22MC1940300);the Cross-Disciplinary Research Fund of Shanghai Ninth People’s Hospital,Shanghai Jiao Tong University School of Medicine(grant no.JYJC202215);the“National Double First-Class”and“Shanghai Top-Level”high education initiative at Shanghai Jiao Tong University School of Medicine and Shanghai Key Research Center-Shanghai Research Center for Plastic Surgery(grant no.2023ZZ02023).
Bioluminescence imaging(BLI)in rodent models has revolutionized preclinical research in recent decades,enabling precise and noninvasive observation of cellular and molecular processes in vivo.Among various bioluminesc...
关键词：Firefly rat Fat grafting LUCIFERASE Stem cells Skin expansion 
Intelligent CAD 2.0
《Visual Informatics》2024年第4期1-12,共12页Qiang Zou Yingcai Wu Zhenyu Liu Weiwei Xu Shuming Gao 
funded by NSF of China (No.62102355),the"Pioneer"and"Leading Goose"R&D Program of Zhejiang Province (No.2024C01103);NSF of Zhejiang Province (No.LQ22F020012);the Fundamental Research Funds for the Zhejiang Provincial Universities (No.2023QZJH32).
Integrating modern artificial intelligence(AI)techniques,particularly generative AI,holds the promise of revolutionizing computer-aided design(CAD)tools and the engineering design process.However,the direction of"AI+C...
关键词：Computer-aided design Artificial intelligence Intelligent CAD 3D generative modeling 3D multimodal modeling 
Age-related changes in behavior profile in male offspring of rats treated with poly I:C-induced maternal immune activation in early gestation
《Animal Models and Experimental Medicine》2024年第6期914-925,共12页Tengfei Chen Huadan Meng Ni Fang Peiling Shi Mengxue Chen Qing Liu Luxian Lv Wenqiang Li 
Xinxiang Medical University;Grant/Award Number:2017ZDCG-04;National Natural Science Foundation of China;Grant/Award Number:81972152 and 82171498;Health Commission of Henan Province,Grant/Award Number:201300310200,212102310589 and LHGJ20190482。
Background:Autism and schizophrenia are environmental risk factors associated with prenatal viral infection during pregnancy.It is still unclear whether behavior phenotypes change at different developmental stages in ...
关键词：behavior maternal immune active poly I:C RAT 
Curative Effect of Spondias mombin L. against Carbon Tetrachloride-Induced Liver Damage in Rat
《Pharmacology & Pharmacy》2024年第12期478-489,共12页Assi Narcisse Roméo Boni Agnon Prisca Djoupo Konan Kouassi Jean-David N’Guessan 
Background: Oxidative stress is implicated in liver disease pathogenesis. Liver injuries are traditionally treated with stem bark from Spondias mombin. In our previous study, this plant demonstrated promising in vitro...
关键词：Oxidative Stress Hepatocurative ANTIOXIDANT Spondias mombin 
Repeated platelet-rich plasma injections improve erectile dysfunction in a rat model of hyperhomocysteinemia被引量：1
《Asian Journal of Andrology》2024年第6期622-627,共6页Zhe Yu Yuan-Zhi Xie Xiao-Lan Huang Su-Zhen Huang Xiang-Min Luo Jin-Xiang Wu 
supported by grants from the Quanzhou Science and Technology Project Funding(No.2021N017S);the Doctoral Nursery Fund of the Second Affiliated Hospital of Fujian Medical University(BS202102).
Platelet-rich plasma (PRP) shows promise as a regenerative modality for mild-to-moderate erectile dysfunction (ED). However, its efficacy in treating severe ED remains unknown. Blood samples from 8-week-old male rats ...
关键词：erectile dysfunction growth factor HYPERHOMOCYSTEINEMIA platelet-rich plasma 
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