CAMS Innovation Fund for Medical Sciences(CIFMS),Grant/Award Number:2021-I2M-1-035;National Natural Science Foundation of China,Grant/Award Number:31970508。
Background:Liver diseases are a major contributor to both morbidity and mortality.Conditional knockout animals are always produced through crossing floxed animals with a tissue-specific Cre animal.The use of floxed ra...
supported by the National Key Research and Development Program of China (2022YFF0710705);the Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences (2021-I2M-1-0 13);funding support from the Special Research Fund for Central Universities;Peking Union Medical College (3332022182);the 111 Project (B20095)
Background:Nuclear receptor-binding SET domain 2(NSD2)is a histone methyltrans-ferase,that catalyzes dimethylation of lysine 36 of histone 3(H3K36me2)and is asso-ciated with active transcription of a series of genes.N...
This work was supported by the National Key Research and Development Program of China(2018YFA0801104 and 2021YFA1301604);the National Natural Science Foundation of China(82372721,31630093,and 82394443);Independent Research Program of the State Key Laboratory of Proteomics(SKLP-K202004).
Endothelial cells(ECs)form a single cell layer that lines the inner surface of all blood and lymphatic vessels,acting as the barrier between vessels and underlying tissues.ECs are not only responsible for the flow of ...