HUMAN

作品数：3951被引量：8431H指数：29
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相关机构：中国科学院北京大学中国科学技术大学清华大学更多>>
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Spatial transcriptomics combined with single-nucleus RNA sequencing reveals glial cell heterogeneity in the human spinal cord
《Neural Regeneration Research》2025年第11期3302-3316,共15页Yali Chen Yiyong Wei Jin Liu Tao Zhu Cheng Zhou Donghang Zhang 
supported by the National Natural Science Foundation of China,No.82301403(to DZ)。
Glial cells play crucial roles in regulating physiological and pathological functions,including sensation,the response to infection and acute injury,and chronic neurodegenerative disorders.Glial cells include astrocyt...
关键词：astrocyte glial cell HUMAN microglia oligodendrocyte sex differentiation single-nucleus RNA sequencing spatial transcriptomics species variation spinal cord 
Effects of P301L-TAU on post-translational modifications of microtubules in human iPSC-derived cortical neurons and TAU transgenic mice
《Neural Regeneration Research》2025年第8期2348-2360,共13页Mohamed Aghyad Al Kabbani Christoph Köhler Hans Zempel 
supported by the Koeln Fortune Program/Faculty of Medicine,University of Cologne,the Alzheimer Forschung Initiative e.V.(grant#22039,to HZ);open-access funding from the DFG/GRC issued to the University of Cologne;Alzheimer Forschung Initiative e.V.for Open Access Publishing(a publication grant#P2401,to MAAK)。
TAU is a microtubule-associated protein that promotes microtubule assembly and stability in the axon.TAU is missorted and aggregated in an array of diseases known as tauopathies.Microtubules are essential for neuronal...
关键词：human induced pluripotent stem cell MICROTUBULES P301L pR5 mice TAU TAUOPATHY tubulin code 
Open and real-world human-AI coordination by heterogeneous training with communication
《Frontiers of Computer Science》2025年第4期59-76,共18页Cong GUAN Ke XUE Chunpeng FAN Feng CHEN Lichao ZHANG Lei YUAN Chao QIAN Yang YU 
supported by the National Key Research and Development Program of China(2020AAA0107200);the National Natural Science Foundation of China(Grant Nos.61921006,61876119,62276126);the Natural Science Foundation of Jiangsu(BK20221442).
Human-AI coordination aims to develop AI agents capable of effectively coordinating with human partners,making it a crucial aspect of cooperative multi-agent reinforcement learning(MARL).Achieving satisfying performan...
关键词：human-AI coordination multi-agent reinforcement learning COMMUNICATION open-environment coordination real-world coordination 
Effect of resistant starch supplementation on the diversity and composition of human gut microbiota:a systematic review and meta-analysis
《Food Science and Human Wellness》2025年第3期850-863,共14页Jiaxin Xu Haocun Kong Caiming Li Xiaofeng Ban Zhaofeng Li 
financially supported by the National Key R&D Program of China(2022YFF1100600,2022YFF1100605);the Science and Technology Support Program(Modern Agriculture)of Jiangsu Province(BE2022323);the National Natural Science Foundation of China(32302011)。
Resistant starch(RS)has attracted much researchers'attention because of its health-beneficial effects.Gut microbiota obviously shapes human health,but the effects of RS supplementation on the changes of human gut micr...
关键词：Resistant starch Gut microbiota META-ANALYSIS HUMAN 
Mitochondrial quality control in human health and disease
《Military Medical Research》2025年第3期393-458,共66页Bo‑Hao Liu Chen‑Zhen Xu Yi Liu Zi‑Long Lu Ting‑Lv Fu Guo‑Rui Li Yu Deng Guo‑Qing Luo Song Ding Ning Li Qing Geng 
supported by the National Natural Science Foundation of China(8210082163,81800343);the Fundamental Research Fund for the Central Universities(2042021kf0081);the Science Fund for Creative Research Groups of the Natural Science Foundation of Hubei Province(2020CFA027);the Doctor of Excellence Program of the First Hospital of Jilin University(JDYY-DEP-2023043).
Mitochondria,the most crucial energy-generating organelles in eukaryotic cells,play a pivotal role in regulating energy metabolism.However,their significance extends beyond this,as they are also indispensable in vital...
关键词：Mitochondrial quality control(MQC) METABOLISM Programmed cell death CANCER Cardiovascular disease Metabolic disease Nervous disease Pulmonary disease Kidney disease Digestive system disease 
Reciprocal regulation between rural settlement expansion and human-elephant conflict in China’s wild elephant range
《Geography and Sustainability》2025年第2期240-252,共13页Beibei Xu Xin Zhang Jiejing Zhang Hui Fan 
supported by the National Natural Science Foundation of China(Grant No.41971239);the Second Tibetan Plateau Scientific Expedition and Research Program(Grant No.2019QZKK0402);Lancang-Mekong Cooperation Project on China-Laos Cross-border Asian Elephant Habitat Quality Assessment(Grant No.102169221100000009022);the Graduate Research Innovation Project of Yunnan University(Grant No.2021Y368).
Human-wildlife conflict(HWC)and its socioeconomic impacts are a pressing global issue.Accurately quantifying HWCs and their interaction with residential development is crucial for rural revitalization and biodiversity...
关键词：Geographical detector Human-elephant conflict Land use/land cover Residential land Spatiotemporal characteristics 
Automatic for the People
《China Weekly》2025年第5期26-27,共2页Zhang Xinyu Deng Yanyang 
Al is now handling paperwork,answering inquiries and even helping draft rulings in some government departments.But where does that leave human employees,and the public they serve?
关键词：AUTOMATION human employees draft rulings public service 
Fenofibrate mitigates the dysfunction of high glucosedriven human retinal microvascular endothelial cells by suppressing NLRP3 inflammasome
《International Journal of Ophthalmology(English edition)》2025年第5期792-801,共10页Yi Shi Hao-Min Chen Ai-Hua Liu Xiao-Rong Li 
Supported by grants from the Tianjin Key Medical Discipline(Specialty)Construction Project(No.TJYXZDXK-037A).
AIM:To determine the therapeutic benefits of fenofibrate(Feno)on the dysfunction of high glucose(HG)-induced human retinal microvascular endothelial cells(HRMECs)and to elucidate the underlying molecular mechanism.MET...
关键词：FENOFIBRATE human retinal microvascular endothelial cells high glucose NOD-like receptor thermal protein domain associated protein 3 inflammasomes oxidative stress 
第十二届食品科学国际年会
《食品科学》2025年第9期I0022-I0027,共6页
通知(第一轮)2025年8月9-10日中国湖南长沙主办:北京食品科学研究院中国食品杂志社《食品科学》杂志(EI收录)中国食品杂志社《Food Science and Human Wellness》杂志(SCI收录)中国食品杂志社《Journal of Future Foods》杂志(ESCI收录...
关键词：食品科学杂志 Food Science and Human Wellness杂志 
The Human Touch China's focus on investing in people is reshaping its economic landscape
《Beijing Review》2025年第14期32-33,共2页Zhang Shasha 
In the city of Ningbo,Zhejiang Province,the lo-govemment has earmarked 10 percent of its ual budget specifically for public services for migrant workers,covering their housing,education and vocational training.This in...
关键词：vocational training human touch GDP growth government investment economic landscape stable employment migrant workersbut migrant workers 
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