云南高校图书馆联盟文献共享服务平台- FENOFIBRATE

FENOFIBRATE: 作品数：50被引量：127H指数：7; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：赵晓燕赵连友蒋青张兴凯李云更多>>; 相关机构：台湾大学解放军第五医院苏州大学南京大学医学院附属鼓楼医院更多>>; 相关期刊：《World Journal of Emergency Medicine》《Case Reports in Clinical Medicine》《World Journal of Hepatology》《Chinese Journal of Natural Medicines》更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划博士科研启动基金上海市浦江人才计划项目更多>>

Fenofibrate mitigates the dysfunction of high glucosedriven human retinal microvascular endothelial cells by suppressing NLRP3 inflammasome: 《International Journal of Ophthalmology(English edition)》2025年第5期792-801,共10页Yi Shi Hao-Min Chen Ai-Hua Liu Xiao-Rong Li; Supported by grants from the Tianjin Key Medical Discipline(Specialty)Construction Project(No.TJYXZDXK-037A).; AIM:To determine the therapeutic benefits of fenofibrate(Feno)on the dysfunction of high glucose(HG)-induced human retinal microvascular endothelial cells(HRMECs)and to elucidate the underlying molecular mechanism.MET...; 关键词：FENOFIBRATE human retinal microvascular endothelial cells high glucose NOD-like receptor thermal protein domain associated protein 3 inflammasomes oxidative stress

Diabetic Ketoacidosis Complicated by Hypertriglyceridemia-Induced Pancreatitis: A Case Report: 《Case Reports in Clinical Medicine》2024年第12期587-596,共10页Imran Khan Adrienne Kwong Caitlin Richler Christine Landry Sydney Morin Pierre Thabet; Background: Diabetic ketoacidosis (DKA) is a severe complication of diabetes characterized by hyperglycemia, metabolic acidosis, and ketosis. It can lead to complications such as hypertriglyceridemia-induced pancreati...; 关键词：Diabetic Ketoacidosis HYPERTRIGLYCERIDEMIA PANCREATITIS Insulin Therapy FENOFIBRATE

Fenofibrate-promoted hepatomegaly and liver regeneration are PPARα-dependent and partially related to the YAP pathway: 《Acta Pharmaceutica Sinica B》2024年第7期2992-3008,共17页Shicheng Fan Yue Gao Pengfei Zhao Guomin Xie Yanying Zhou Xiao Yang Xuan Li Shuaishuai Zhang Frank JGonzalez Aijuan Qu Min Huangb Huichang Bi; supported by the National Key R&D Program of China(2022YFA1104900 to Huichang Bi,2022YFA1106700 to Xiao Yang);the National Natural Science Foundation of China(grants 82025034 and U23A20535 to Huichang Bi,grants 82304603 to Shicheng Fan);the Shenzhen Science and Technology Program(No.KQTD20190929174023858 to Huichang Bi,China);the Science and Technology Innovation Project of Guangdong Medical Products Administration(2023ZDZ06 to Huichang Bi,China);the National Postdoctoral Program for Innovative Talents(BX20230151 to Shicheng Fan,China);the China Postdoctoral Science Foundation(2023M731570 to Shicheng Fan);the Guangdong Basic and Applied Basic Research Foundation(2023A1515012859 to Shicheng Fan,China);the Guangdong Medical Research Foundation(A2023109 to Shicheng Fan,China).; Fenofibrate,a peroxisome proliferator-activated receptor α(PPARα)agonist,is widely prescribed for hyperlipidemia management.Recent studies also showed that it has therapeutic potential in various liver diseases.Howe...; 关键词：FENOFIBRATE PPARa HEPATOMEGALY Partial hepatectomy Liver regeneration YAP TEAD UBIQUITINATION

When the Stars Align: Hypertriglyceridemic Pancreatitis Is Inevitable: 《International Journal of Clinical Medicine》2024年第7期233-239,共7页Kamel El-Reshaid Abass Hakim Reji Philip Athyal; Background: Acute pancreatitis (AP) is an inflammatory process affecting the pancreas. Hypertriglyceridemic AP (HTAP) is its third leading cause after gallstones followed by alcohol use. It develops when stars align v...; 关键词：FENOFIBRATE Genetic Hypertriglyceridemia HYPERLIPIDEMIA PANCREATITIS TRIGGERS Weight Reduction

硬脂酰辅酶A去饱和酶1通过抑制肺上皮细胞铁死亡缓解小鼠特发性肺纤维化进展的作用研究被引量：1: 《中南药学》2024年第5期1141-1149,共9页吴趋荟李妲符艳侯钰丛张琴金朝晖; 湖南省卫健委重点项目(No.202203023299);长沙市自然科学基金项目(No.kq2202455);湖南省教育厅科学研究项目(No.22A0252)。; 目的拟利用基因敲除小鼠和细胞系研究硬脂酰辅酶 A 去饱和酶 1(SCD1)在特发性肺纤维化(IPF)中的作用及机制。方法利用SCD1条件敲除小鼠和BEAS-2B细胞,比较SCD1敲除或敲低后组织学改变和铁死亡变化,并研究PPARα激动剂Fenofibrate对SCD...; 关键词：特发性肺纤维化铁死亡硬脂酰辅酶A去饱和酶1 FENOFIBRATE

Influence of Statins and Fibrates Drugs on Bone Health and Regeneration: 《Journal of Biomaterials and Nanobiotechnology》2024年第1期1-24,共24页Octavio Santiago Ivan Nadir Camal Ruggieri Marina Ribeiro Paulini Valéria Paula Sassoli Fazan João Paulo Mardegan Issa Sara Feldman; In the medical and dental field, the importance and need for the study of materials and drugs for use as bone grafts or regeneration in injured areas due to the presence of fractures, infections or tumors that cause e...; 关键词：Bone STATINS ROSUVASTATIN Sinvastatin FIBRATES FENOFIBRATE Bone Regeneration

Fenofibrate in a patient with primary biliary cholangitis with an inadequate response to bezafibrate: 《Portal Hypertension & Cirrhosis》2023年第4期192-193,共2页Yangyang Zhou Haonan Gao Yuhu Song; supported by the National Natural Science Foundation of China(No.82070631).; To the Editor,A 48-year-old male patient presented to our hospital with abnormal liver function.The results of his liver function tests were as follows:alanine transaminase,118 U/L(normal range,5-35 U/L);aspartate tra...; 关键词：PATIENT function liver

Hemorrhagic pancreatitis from fenofibrate and metformin toxicity:a case report: 《World Journal of Emergency Medicine》2023年第6期495-498,共4页Marcus Aik Beng Lee Mingwei Ng Paul Yugendra Yiju Yao R Ponampalam Boon Kiat Kenneth Tan; Fibrates have been used for over forty-odd years to manage dyslipidemia and are generally considered safe and well-tolerated.^([1])However,little is known about the toxicity offibrates in overdose,[2]and most of the k...; 关键词：doses PANCREATITIS

Fenofibrate for the prevention of progression of non-proliferative diabetic retinopathy:review,consensus recommendations and guidance for clinical practice被引量：2: 《International Journal of Ophthalmology(English edition)》2022年第12期2001-2008,共8页Nor Fariza Ngah Nor Asiah Muhamad Roslin Azni Abdul Aziz Shelina Oli Mohamed Nor Azita Ahmad Tarmizi Azian Adnan Zalifah Zakiah Asnir Zanariah Hussein Hui Foo Siew Masni Mohamed Noor Aliza Lodz Vijayamala Valayatham; The prevalence of diabetic retinopathy(DR),and associated morbidity is high in the Asia-Pacific region.Emerging evidence suggests a potential role for fenofibrate in the prevention of progression of DR,especially in p...; 关键词：diabetic retinopathy FENOFIBRATE consensus recommendations

Rod-like mesoporous silica nanoparticles facilitate oral drug delivery via enhanced permeation and retention effect in mucus: 《Nano Research》2022年第10期9243-9252,共10页Wenjuan Liu Luyu Zhang Zirong Dong Kaiheng Liu Haisheng He Yi Lu Wei Wu Jianping Qi; supported by the National Natural Science Foundation of China(No.81872826);the Science and Technology Commission of Shanghai Municipality(No.18ZR1404100);the Shanghai Pujiang Program(No.18PJD001).; The physiochemical characteristics of nanoparticles affect their in vitro and in vivo performance significantly,such as diameter,surface chemistry,and shape.This paper disclosed the effect of enhanced permeation and r...; 关键词：mesoporous silica nanoparticles shape effect FENOFIBRATE mucus layer enhanced permeation and retention effect

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